{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T05:08:15Z","timestamp":1772168895503,"version":"3.50.1"},"update-to":[{"DOI":"10.12688\/f1000research.140514.1","type":"new_version","label":"New version","source":"publisher","updated":{"date-parts":[[2024,6,28]],"date-time":"2024-06-28T00:00:00Z","timestamp":1719532800000}}],"reference-count":15,"publisher":"F1000 Research Ltd","license":[{"start":{"date-parts":[[2024,6,28]],"date-time":"2024-06-28T00:00:00Z","timestamp":1719532800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100019779","name":"Qatar National Library","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100019779","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["f1000research.com"],"crossmark-restriction":false},"short-container-title":["F1000Res"],"abstract":"<ns4:p>Background Coronavirus (COVID-19) is the causative agent of the most recent pandemic that hit the globe and has been the cause of a vast range of symptoms, including neurological symptoms. Bell\u2019s palsy is an acute peripheral facial paralysis commonly associated with viral infections. Case presentation This case report describes a patient with incidental COVID-19 infection that led to acute unilateral peripheral facial paralysis, Bell\u2019s palsy. Our patient is a 35-year-old male with no known comorbidities who was presenting with upper respiratory tract infection symptoms and was found to be positive for COVID-19. Soon after the onset of symptoms, he also developed right-sided facial weakness in association with his symptoms. A thorough examination revealed a peripheral neurological lesion. The diagnosis of Bell\u2019s palsy secondary to COVID-19 virus infection was through the exclusion of other possible causes. Conclusions This case report suggests a potential link between Bell\u2019s palsy and COVID-19, highlighting the importance of a comprehensive understanding of the neurological manifestations of COVID-19. Further research is essential to determine the significance of neuropathies in COVID-19 and enhance treatment strategies.<\/ns4:p>","DOI":"10.12688\/f1000research.140514.2","type":"journal-article","created":{"date-parts":[[2024,7,11]],"date-time":"2024-07-11T11:03:39Z","timestamp":1720695819000},"page":"1355","update-policy":"https:\/\/doi.org\/10.12688\/f1000research.crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Case Report: Bell\u2019s palsy: a neurological manifestation of COVID-19 infection"],"prefix":"10.12688","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3113-3431","authenticated-orcid":false,"given":"Amro","family":"Abdelrahman","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3725-8537","authenticated-orcid":false,"given":"Amira","family":"Bitar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isra","family":"Babiker","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fawaz","family":"Elgak","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-8454-132X","authenticated-orcid":false,"given":"Mohamed","family":"Elgassim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2560","published-online":{"date-parts":[[2024,6,28]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"m1091","DOI":"10.1136\/bmj.m1091","article-title":"Clinical characteristics of 113 deceased patients with coronavirus disease 2019: retrospective study [published correction appears in BMJ. 2020 Mar 31;368:m1295].","volume":"368","author":"T Chen","year":"2020","journal-title":"BMJ."},{"key":"ref2","doi-asserted-by":"publisher","first-page":"364-367","DOI":"10.1212\/WNL.0000000000009863","article-title":"Pearls & Oy-sters: Facial nerve palsy in COVID-19 infection.","volume":"95","author":"Y Goh","year":"2020","journal-title":"Neurology."},{"key":"ref3","doi-asserted-by":"publisher","first-page":"941-944","DOI":"10.1007\/s13365-020-00912-6","article-title":"Peripheral facial nerve palsy associated with COVID-19.","volume":"26","author":"M Lima","year":"2020","journal-title":"J Neurovirol."},{"key":"ref4","doi-asserted-by":"publisher","first-page":"1-4","DOI":"10.1017\/S0022215120002121","article-title":"A rise in facial nerve palsies during the coronavirus disease 2019 pandemic [published online ahead of print, 2020 Oct 1].","author":"M Zammit","year":"2020","journal-title":"J Laryngol Otol."},{"key":"ref5","doi-asserted-by":"publisher","first-page":"105921","DOI":"10.1016\/j.clineuro.2020.105921","article-title":"Neurological manifestations of COVID-19 and other coronavirus infections: A systematic review.","volume":"194","author":"V Montalvan","year":"2020","journal-title":"Clin Neurol Neurosurg."},{"key":"ref6","doi-asserted-by":"publisher","first-page":"167-173","DOI":"10.1007\/s11481-020-09924-9","article-title":"SARS-CoV-2 Infection Leads to Neurological Dysfunction.","volume":"15","author":"A Acharya","year":"2020","journal-title":"J Neuroimmune Pharmacol."},{"key":"ref7","doi-asserted-by":"publisher","first-page":"e00404-e00418","DOI":"10.1128\/JVI.00404-18","article-title":"Axonal Transport Enables Neuron-to-Neuron Propagation of Human Coronavirus OC43.","volume":"92","author":"M Dub\u00e9","year":"2018","journal-title":"J Virol."},{"key":"ref8","doi-asserted-by":"publisher","first-page":"3398-3406","DOI":"10.1128\/jvi.78.7.3398-3406.2004","article-title":"Coronavirus neurovirulence correlates with the ability of the virus to induce pro-inflammatory cytokine signals from astrocytes and microglia.","volume":"78","author":"Y Li","year":"2004","journal-title":"J Virol."},{"key":"ref9","doi-asserted-by":"publisher","first-page":"e7352","DOI":"10.7759\/cureus.7352","article-title":"Neurological Complications of Coronavirus Disease (COVID-19): Encephalopathy.","volume":"12","author":"A Filatov","year":"2020","journal-title":"Cureus."},{"key":"ref10","doi-asserted-by":"publisher","first-page":"e601-e605","DOI":"10.1212\/WNL.0000000000009619","article-title":"Miller Fisher syndrome and polyneuritis cranialis in COVID-19.","volume":"95","author":"C Guti\u00e9rrez-Ortiz","year":"2020","journal-title":"Neurology."},{"key":"ref11","doi-asserted-by":"publisher","first-page":"1707-1713","DOI":"10.1007\/s42399-021-00967-4","article-title":"Can COVID-19 Cause Peripheral Facial Nerve Palsy?","volume":"3","author":"O Egilmez","year":"2021","journal-title":"SN Compr Clin Med."},{"key":"ref12","doi-asserted-by":"publisher","first-page":"e13881","DOI":"10.7759\/cureus.13881","article-title":"Bell\u2019s Palsy as a Late Neurologic Manifestation of COVID-19 Infection.","volume":"13","author":"I Oke","year":"2021","journal-title":"Cureus."},{"key":"ref13","doi-asserted-by":"publisher","first-page":"24-36","DOI":"10.5606\/Tr-ENT.2020.26817","article-title":"Approach to otolaryngology emergency in COVID-19 pandemic.","volume":"30","author":"B \u00c7aytemel","year":"2020","journal-title":"Tr-ENT."},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.330.7504.1374","article-title":"Bell\u2019s Palsy.","author":"J Piercy","year":"2005","journal-title":"The BMJ."},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.5281\/zenodo.8359632","author":"A Abdelrahman","year":"2023","journal-title":"Zenodo."}],"container-title":["F1000Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/f1000research.com\/articles\/12-1355\/v2\/xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/f1000research.com\/articles\/12-1355\/v2\/pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/f1000research.com\/articles\/12-1355\/v2\/iparadigms","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,12,28]],"date-time":"2024-12-28T02:10:10Z","timestamp":1735351810000},"score":1,"resource":{"primary":{"URL":"https:\/\/f1000research.com\/articles\/12-1355\/v2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,6,28]]},"references-count":15,"URL":"https:\/\/doi.org\/10.12688\/f1000research.140514.2","relation":{"has-version":[{"id-type":"doi","id":"10.12688\/f1000research.140514.1","asserted-by":"subject"}],"has-review":[{"id-type":"doi","id":"10.5256\/f1000research.168370.r328968","asserted-by":"subject"},{"id-type":"doi","id":"10.5256\/f1000research.168370.r346701","asserted-by":"subject"},{"id-type":"doi","id":"10.5256\/f1000research.168370.r296810","asserted-by":"subject"},{"id-type":"doi","id":"10.5256\/f1000research.168370.r328968","asserted-by":"object"},{"id-type":"doi","id":"10.5256\/f1000research.168370.r346701","asserted-by":"object"},{"id-type":"doi","id":"10.5256\/f1000research.168370.r296810","asserted-by":"object"}]},"ISSN":["2046-1402"],"issn-type":[{"value":"2046-1402","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,6,28]]},"assertion":[{"value":"Indexed","URL":"https:\/\/f1000research.com\/articles\/12-1355\/v2#article-reports","order":0,"name":"referee-status","label":"Referee status","group":{"name":"current-referee-status","label":"Current Referee Status"}},{"value":"10.5256\/f1000research.168370.r296810, Sohyeon Kim, Department of Neurology, Keimyung University, Daegu, 16 Jul 2024, version 2, indexed","URL":"https:\/\/f1000research.com\/articles\/12-1355\/v2#referee-response-296810","order":0,"name":"referee-response-296810","label":"Referee Report","group":{"name":"article-reports","label":"Article Reports"}},{"value":"10.5256\/f1000research.168370.r346701, Isabel Vilaseca, Universitat de Barcelona, Barcelona, Catalonia, 26 Dec 2024, version 2, indexed","URL":"https:\/\/f1000research.com\/articles\/12-1355\/v2#referee-response-346701","order":1,"name":"referee-response-346701","label":"Referee Report","group":{"name":"article-reports","label":"Article Reports"}},{"value":"10.5256\/f1000research.168370.r328968, Josef Finsterer, Neurology and Neurophysiology Center,, Vienna, 28 Dec 2024, version 2, indexed","URL":"https:\/\/f1000research.com\/articles\/12-1355\/v2#referee-response-328968","order":2,"name":"referee-response-328968","label":"Referee Report","group":{"name":"article-reports","label":"Article Reports"}},{"value":"Open Access funding was provided by the Qatar National Library. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.","order":3,"name":"grant-information","label":"Grant Information"},{"value":"This is an open access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.","order":0,"name":"copyright-info","label":"Copyright"}]}}