{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,13]],"date-time":"2026-04-13T12:41:26Z","timestamp":1776084086459,"version":"3.50.1"},"reference-count":10,"publisher":"F1000 Research Ltd","license":[{"start":{"date-parts":[[2018,6,28]],"date-time":"2018-06-28T00:00:00Z","timestamp":1530144000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["f1000research.com"],"crossmark-restriction":false},"short-container-title":["F1000Res"],"abstract":"<ns4:p>\n                    <ns4:bold>Background:<\/ns4:bold>\n                    Bronchogenic cysts are congenital malformations from abnormal budding of embryonic foregut and tracheobronchial tree. We present a case of bronchogenic cyst with severe back pain, epigastric distress and refractory nausea and vomiting. \u00a0\n                  <\/ns4:p>\n                  <ns4:p>\n                    <ns4:bold>Case Presentation:<\/ns4:bold>\n                    A 44-year-old Hispanic female presented with a 3-week history of recurrent sharp interscapular pain radiating to epigastrium with refractory nausea and vomiting. She underwent cholecystectomy 2-years ago. Computed tomography (CT) abdomen at that time showed a subcarinal mass measuring 5.4 X 5.0 cm. Subsequent endoscopic ultrasound diagnosed it as a bronchogenic cyst. Endobronchial ultrasound (EBUS) guided aspiration resulted in incomplete drainage and she was discharged after partial improvement. Current physical examination showed tachycardia and tachypnea with labs showing leukocytosis, elevated inflammatory markers, and hypokalemic metabolic alkalosis. CT chest showed an increased size of the bronchogenic cyst (9.64 X 7.7 cm) suggestive of possible partial cyst rupture or infected cyst. X-ray esophagram ruled out esophageal compression or contrast extravasation. Patient\u2019s symptoms were refractory to conservative management. The patient ultimately underwent right thoracotomy with cyst excision that resulted in complete resolution of symptoms.\n                  <\/ns4:p>\n                  <ns4:p>\n                    <ns4:bold>Conclusion:<\/ns4:bold>\n                    Bronchogenic cysts are the most common primary cysts of mediastinum with the prevalence of 6%. The most common symptoms are chest pain, dyspnea, cough, and stridor. Diagnosis is made by chest X-Ray and CT chest. Magnetic resonance imaging chest and EBUS are more sensitive and specific. Symptomatic cysts should be resected unless surgical risks are high. Asymptomatic cysts in younger patients should be removed due to low surgical risk and potential late complications. Watchful waiting has been recommended for asymptomatic adults or high-risk patients.\n                  <\/ns4:p>\n                  <ns4:p>This case presents mediastinal bronchogenic cyst as a cause of back, nausea and refractory vomiting. Immediate surgical excision in such cases should be attempted, which will lead to resolution of symptoms and avoidance of complications.<\/ns4:p>","DOI":"10.12688\/f1000research.15128.1","type":"journal-article","created":{"date-parts":[[2018,6,28]],"date-time":"2018-06-28T07:01:12Z","timestamp":1530169272000},"page":"960","update-policy":"https:\/\/doi.org\/10.12688\/f1000research.crossmark-policy","source":"Crossref","is-referenced-by-count":8,"title":["Case Report: Severe back pain, epigastric distress and refractory nausea; an unusual presentation of mediastinal bronchogenic cyst"],"prefix":"10.12688","volume":"7","author":[{"given":"Saeed","family":"Ali","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abdul","family":"Rauf","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ling Bing","family":"Meng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0133-0645","authenticated-orcid":false,"given":"Zeeshan","family":"Sattar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sana","family":"Hussain","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Umair","family":"Majeed","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2560","published-online":{"date-parts":[[2018,6,28]]},"reference":[{"key":"ref-1","doi-asserted-by":"publisher","first-page":"55-61","DOI":"10.1007\/s00408-007-9056-4","article-title":"Pulmonary and mediastinal bronchogenic cysts: a clinicopathologic study of 33 cases.","volume":"186","author":"F Lima\u00efem","year":"2008","journal-title":"Lung."},{"key":"ref-2","first-page":"2090-1","article-title":"Primary neoplasms and cysts of the mediastinum.","volume":"3","author":"H Lyerly","year":"1988","journal-title":"Pulmonary diseases and disorders."},{"key":"ref-3","doi-asserted-by":"publisher","first-page":"441-6","DOI":"10.1148\/radiology.217.2.r00nv19441","article-title":"Bronchogenic cyst: imaging features with clinical and histopathologic correlation.","volume":"217","author":"H McAdams","year":"2000","journal-title":"Radiology."},{"key":"ref-4","doi-asserted-by":"publisher","first-page":"86-8","DOI":"10.4103\/0970-2113.63612","article-title":"Mediastinal bronchogenic cyst presenting with dysphagia and back pain.","volume":"27","author":"M Tiwari","year":"2010","journal-title":"Lung India."},{"key":"ref-5","doi-asserted-by":"publisher","first-page":"11-4","DOI":"10.1016\/S1015-9584(11)60012-2","article-title":"Thoracoscopic resection of mediastinal bronchogenic cysts in adults.","volume":"34","author":"T Muramatsu","year":"2011","journal-title":"Asian J Surg."},{"key":"ref-6","doi-asserted-by":"publisher","first-page":"987-91","DOI":"10.1016\/j.athoracsur.2004.03.092","article-title":"Video-assisted thoracoscopic surgery of mediastinal bronchogenic cysts in adults: a single-center experience.","volume":"78","author":"T Weber","year":"2004","journal-title":"Ann Thorac Surg."},{"key":"ref-7","doi-asserted-by":"publisher","first-page":"370-4","DOI":"10.5761\/atcs.cr.16-00086","article-title":"Lipoma-Like Bronchogenic Cyst in the Right Chest Sidewall: A Case Report and Literature Review.","volume":"22","author":"W Che","year":"2016","journal-title":"Ann Thorac Cardiovasc Surg."},{"key":"ref-8","doi-asserted-by":"publisher","first-page":"287-8","DOI":"10.1510\/icvts.2005.108050","article-title":"Intra-esophageal rupture of a bronchogenic cyst.","volume":"4","author":"O Pages","year":"2005","journal-title":"Interact Cardiovasc Thorac Surg."},{"key":"ref-9","article-title":"Severe Back Pain, Epigastric Distress and Refractory Nausea: An Unusual Presentation of Mediastinal Bronchogenic Cyst","year":"2017"},{"key":"ref-10","doi-asserted-by":"publisher","first-page":"79-85","DOI":"10.1378\/chest.106.1.79","article-title":"Presentation and management of bronchogenic cysts in the adult.","volume":"106","author":"S Patel","year":"1994","journal-title":"Chest."}],"container-title":["F1000Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/f1000research.com\/articles\/7-960\/v1\/pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/f1000research.com\/articles\/7-960\/v1\/xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/f1000research.com\/articles\/7-960\/v1\/iparadigms","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,12,6]],"date-time":"2018-12-06T15:57:19Z","timestamp":1544111839000},"score":1,"resource":{"primary":{"URL":"https:\/\/f1000research.com\/articles\/7-960\/v1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,6,28]]},"references-count":10,"URL":"https:\/\/doi.org\/10.12688\/f1000research.15128.1","relation":{"has-review":[{"id-type":"doi","id":"10.5256\/f1000research.16481.r37985","asserted-by":"subject"},{"id-type":"doi","id":"10.5256\/f1000research.16481.r37054","asserted-by":"subject"},{"id-type":"doi","id":"10.5256\/f1000research.16481.r37985","asserted-by":"object"},{"id-type":"doi","id":"10.5256\/f1000research.16481.r37054","asserted-by":"object"}]},"ISSN":["2046-1402"],"issn-type":[{"value":"2046-1402","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,6,28]]},"assertion":[{"value":"Indexed","URL":"https:\/\/f1000research.com\/articles\/7-960\/v1#article-reports","order":0,"name":"referee-status","label":"Referee status","group":{"name":"current-referee-status","label":"Current Referee Status"}},{"value":"10.5256\/f1000research.16481.r37054, Dipak K. Mukherjee, Department of Respiratory Medicine, Basildon and Thurrock University Hospital, Basildon, UK, 19 Sep 2018, version 1, indexed","URL":"https:\/\/f1000research.com\/articles\/7-960\/v1#referee-response-37054","order":0,"name":"referee-response-37054","label":"Referee Report","group":{"name":"article-reports","label":"Article Reports"}},{"value":"10.5256\/f1000research.16481.r37985, Ali Dahhan, University of Louisville, Louisville, Louisville, KY, USA, 20 Sep 2018, version 1, indexed","URL":"https:\/\/f1000research.com\/articles\/7-960\/v1#referee-response-37985","order":1,"name":"referee-response-37985","label":"Referee Report","group":{"name":"article-reports","label":"Article Reports"}},{"value":"The author(s) declared that no grants were involved in supporting this work","order":2,"name":"grant-information","label":"Grant Information"},{"value":"This is an open access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.","order":0,"name":"copyright-info","label":"Copyright"}]}}