{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,29]],"date-time":"2026-08-29T16:36:51Z","timestamp":1788021411281,"version":"build-2784847793"},"update-to":[{"DOI":"10.12688\/f1000research.15344.1","type":"new_version","label":"New version","source":"publisher","updated":{"date-parts":[[2019,6,18]],"date-time":"2019-06-18T00:00:00Z","timestamp":1560816000000}},{"DOI":"10.12688\/f1000research.15344.2","type":"new_version","label":"New version","source":"publisher","updated":{"date-parts":[[2019,6,18]],"date-time":"2019-06-18T00:00:00Z","timestamp":1560816000000}}],"reference-count":39,"publisher":"F1000 Research Ltd","license":[{"start":{"date-parts":[[2019,6,18]],"date-time":"2019-06-18T00:00:00Z","timestamp":1560816000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["f1000research.com"],"crossmark-restriction":false},"short-container-title":["F1000Res"],"abstract":"<ns4:p>\n                    <ns4:bold>Background<\/ns4:bold>\n                    : Toxoplasmosis is a globally distributed parasitic disease. The present study aimed to estimate the prevalence and geographic distribution of toxoplasmosis as well as determine the percentage of toxoplasmosis-associated IgM and IgG seropositivity among different age groups. In addition, it aimed to estimate the proportion of toxoplasma IgM seropositivity among pregnancy trimesters.\n                  <\/ns4:p>\n                  <ns4:p>\n                    <ns4:bold>Methods<\/ns4:bold>\n                    : A total of 500 pregnant women were included in this study. From each participant, a 5-ml venous blood sample was collected and centrifuged to obtain serum that was tested for Toxoplasma gondii IgM and IgG antibodies using immunochromatographic testing and ELISA.\n                  <\/ns4:p>\n                  <ns4:p>\n                    <ns4:bold>Results<\/ns4:bold>\n                    : The overall seroprevalence of toxoplasmosis was 24.8%. Out of the total of 500 participants, only 8% had a serological marker of acute toxoplasmosis). There is a statistically significant difference in the seroprevalence of disease among the study areas. Amongst positive cases of every trimester, 54.34% of first trimester positive cases had a serologic marker for acute toxoplasmosis.\u00a0\n                  <\/ns4:p>\n                  <ns4:p>\n                    <ns4:bold>Conclusions<\/ns4:bold>\n                    : In this study, there is a high prevalence of toxoplasmosis. Therefore, it is necessary to test every pregnant woman for toxoplasmosis and distinguish the type of infection, as well as the conduction of public health education programs to generate the awareness.\n                  <\/ns4:p>","DOI":"10.12688\/f1000research.15344.3","type":"journal-article","created":{"date-parts":[[2019,6,18]],"date-time":"2019-06-18T04:30:19Z","timestamp":1560832219000},"page":"1823","update-policy":"https:\/\/doi.org\/10.12688\/f1000research.crossmark-policy","source":"Crossref","is-referenced-by-count":6,"title":["Distribution of Toxoplasma gondii IgM and IgG antibody seropositivity among age groups and gestational periods in pregnant women"],"prefix":"10.12688","volume":"7","author":[{"given":"Shahida","family":"Sadiqui","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Syed Rafiq 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Sabin","year":"1942","journal-title":"AdvPediatr."},{"key":"ref-8","doi-asserted-by":"publisher","first-page":"426-30","DOI":"10.1016\/S0966-842X(03)00205-1","article-title":"Migration of Toxoplasma gondii across biological barriers.","volume":"11","author":"A Barragan","year":"2003","journal-title":"Trends Microbiol."},{"key":"ref-9","doi-asserted-by":"publisher","first-page":"351-4","DOI":"10.1016\/S0002-9394(00)00830-8","article-title":"A follow-up study of Toxoplasma gondii infection in southern Brazil.","volume":"131","author":"C Silveira","year":"2001","journal-title":"Am J Ophth."},{"key":"ref-10","article-title":"Toxoplasmosis","author":"M Hokelek","year":"2006"},{"key":"ref-11","first-page":"160-165","article-title":"Toxoplasmosis in HIV\/AIDS patients: a current situation.","volume":"57","author":"V Nissapatorn","year":"2004","journal-title":"Jpn J Infect Dis."},{"key":"ref-12","doi-asserted-by":"publisher","first-page":"211-222","DOI":"10.1093\/clinids\/15.2.211","article-title":"Toxoplasmic encephalitis in AIDS.","volume":"15","author":"B Luft","year":"1992","journal-title":"Clin Infect Dis."},{"key":"ref-13","doi-asserted-by":"publisher","first-page":"1375-1424","DOI":"10.1017\/S0031182012000765","article-title":"Toxoplasmosis in humans and animals in Brazil: high prevalence, high burden of disease, and epidemiology.","volume":"139","author":"J Dubey","year":"2012","journal-title":"Parasitology."},{"key":"ref-14","doi-asserted-by":"publisher","first-page":"1965-1976","DOI":"10.1016\/S0140-6736(04)16412-X","article-title":"Toxoplasmosis.","volume":"363","author":"J Montoya","year":"2004","journal-title":"Lancet."},{"key":"ref-15","first-page":"2278-2280","article-title":"Detection of Toxoplasma gondii oocysts in drinking water.","volume":"64","author":"J Dubey","year":"1998","journal-title":"App Env Micro."},{"key":"ref-16","article-title":"Toxoplasmosis Medicine","author":"L Wu","year":"2011"},{"key":"ref-17","first-page":"1-11","article-title":"Toxoplasmosis: Emerging and Re-Emerging zoonosis.","volume":"3","author":"Y Muhie","year":"2014","journal-title":"Afr J of App Micro."},{"key":"ref-18","first-page":"384-8","article-title":"Occular manifestation of toxoplasmosis.","volume":"14","author":"A Rothova","year":"2003","journal-title":"Curr open Opthalmol."},{"key":"ref-19","doi-asserted-by":"publisher","first-page":"564-71","DOI":"10.1016\/j.ajog.2004.07.031","article-title":"Risk factors for Toxoplasma gondii infection in mothers of infants with congenital toxoplasmosis: Implications for prenatal management and screening.","volume":"19","author":"K Boyer","year":"2005","journal-title":"Am J Obstet Gynecol."},{"key":"ref-20","doi-asserted-by":"publisher","first-page":"161-5","DOI":"10.1080\/10647440500068305","article-title":"Prevention of toxoplasmosis in pregnancy: knowledge of risk factors.","volume":"13","author":"J Kravetz","year":"2005","journal-title":"Infect Dis Obstet Gynecol."},{"key":"ref-21","first-page":"28-32","article-title":"Materno-fetal Toxoplasma gondii infection: critical review of available diagnostic methods.","volume":"16","author":"D Carlo","year":"2008","journal-title":"Inf Med."},{"key":"ref-22","first-page":"2131-8","article-title":"Congenital toxoplasmosis.","volume":"67","author":"J Jones","year":"2003","journal-title":"Am Fam Physician."},{"key":"ref-23","doi-asserted-by":"crossref","first-page":"107-37","DOI":"10.1016\/S0950-3552(05)80149-X","article-title":"Toxoplasmosis in pregnancy.","volume":"7","author":"B Stray-Pedersen","year":"1993","journal-title":"Baillieres Clin Obstet Gynaecol."},{"key":"ref-24","doi-asserted-by":"publisher","first-page":"1511-4","DOI":"10.1136\/bmj.318.7197.1511","article-title":"Congenital toxoplasmosis: systematic review of evidence of efficacy of treatment in pregnancy.","volume":"318","author":"M Wallon","year":"1999","journal-title":"BMJ."},{"key":"ref-25","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD001684","article-title":"Treatments for toxoplasmosis in pregnancy.","volume":"I3","author":"F Peyron","year":"2000","journal-title":"Cochrane Database Syst Rev."},{"key":"ref-26","doi-asserted-by":"publisher","first-page":"793-8","DOI":"10.4269\/ajtmh.1999.60.793","article-title":"Risk factors for infection with Toxoplasma gondii for residents and workers on swine farms in Illinois.","volume":"60","author":"R Weigel","year":"1999","journal-title":"Am J Trop Med Hyg."},{"key":"ref-27","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1186\/1471-2334-14-33","article-title":"Congenital toxoplasmosis and prenatal care state programs.","volume":"14","author":"M Avelino","year":"2014","journal-title":"BMC Infect 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J."},{"key":"ref-32","doi-asserted-by":"publisher","first-page":"69-71","DOI":"10.3347\/kjp.2005.43.2.69","article-title":"Seroprevalence of toxoplasmosis in Korean pregnant women.","volume":"43","author":"K Song","year":"2005","journal-title":"Korean J Parasitol."},{"key":"ref-33","doi-asserted-by":"publisher","first-page":"97-104","DOI":"10.3109\/00365549209048407","article-title":"Incidence of primary toxoplasma infections during pregnancy in southern Finland: a prospective cohort study.","volume":"24","author":"M Lappalainen","year":"1992","journal-title":"Scand J Infect Dis."},{"key":"ref-34","doi-asserted-by":"publisher","first-page":"199-204","DOI":"10.14411\/fp.2005.026","article-title":"Influence of latent 'asymptomatic' toxoplasmosis on body weight of pregnant women.","volume":"52","author":"J Flegr","year":"2005","journal-title":"Folia Parasitol (Praha)."},{"key":"ref-35","doi-asserted-by":"publisher","first-page":"207-219","DOI":"10.1016\/0021-9975(92)90037-U","article-title":"An epidemic of toxoplasmosis in a captive colony of squirrel monkeys (Saimiri sciureus).","volume":"107","author":"A Cunningham","year":"1992","journal-title":"J Comp Pathol."},{"key":"ref-36","doi-asserted-by":"publisher","first-page":"305-9","DOI":"10.1080\/00365549950163626","article-title":"Risk factors for Toxoplasma infection in pregnancy: a case-control study in France.","volume":"31","author":"L Baril","year":"1999","journal-title":"Scand J Infect Dis."},{"key":"ref-37","first-page":"868-70","article-title":"Toxoplasmosis in pregnant Sudanese women.","volume":"24","author":"A Elnahas","year":"2003","journal-title":"Saudi Med J."},{"key":"ref-38","article-title":"Serological evidence of Toxoplasma gondii infection among pregnant women in Auckland.","volume":"117","author":"A Morris","year":"2004","journal-title":"N Z Med J."},{"key":"ref-39","doi-asserted-by":"crossref","first-page":"1823","DOI":"10.12688\/f1000research.15344.3","article-title":"Dataset 1 in: Distribution of Toxoplasma gondii IgM and IgG antibody seropositivity among age groups and gestational periods in pregnant women.","volume":"24","author":"S 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grants were involved in supporting this work","order":2,"name":"grant-information","label":"Grant Information"},{"value":"This is an open access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.","order":0,"name":"copyright-info","label":"Copyright"}]}}