{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T05:08:47Z","timestamp":1772168927984,"version":"3.50.1"},"update-to":[{"DOI":"10.12688\/f1000research.16326.1","type":"new_version","label":"New version","source":"publisher","updated":{"date-parts":[[2019,7,1]],"date-time":"2019-07-01T00:00:00Z","timestamp":1561939200000}}],"reference-count":13,"publisher":"F1000 Research Ltd","license":[{"start":{"date-parts":[[2019,7,1]],"date-time":"2019-07-01T00:00:00Z","timestamp":1561939200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["f1000research.com"],"crossmark-restriction":false},"short-container-title":["F1000Res"],"abstract":"<ns4:p>Exertional rhabdomyolysis is more common in sickle trait due to a predisposition to dehydration and inability to concentrate the urine. Spinning, an indoor cycling workout, has been associated with exertional rhabdomyolysis in recent reports. A consequence of rhabdomyolysis is acute kidney injury, which may be expected to be more common in patients with sickle trait. We report a case of spinning induced rhabdomyolysis in a woman with sickle trait that did not result in renal injury. \u201cSpin rhabdo\u201d is thought to be more severe than other causes of exertional rhabdomyolysis and is associated with higher creatine kinase levels than other causes of exertional rhabdomyolysis. Therefore, individuals with known sickle trait should consider visiting their physician prior to participation in spin classes for the first time. We might also consider voluntary screening for sickle trait in at risk populations prior to enrolling in spin classes given that many patients are unaware of their sickle trait status.<\/ns4:p>","DOI":"10.12688\/f1000research.16326.2","type":"journal-article","created":{"date-parts":[[2019,7,1]],"date-time":"2019-07-01T04:05:09Z","timestamp":1561953909000},"page":"1742","update-policy":"https:\/\/doi.org\/10.12688\/f1000research.crossmark-policy","source":"Crossref","is-referenced-by-count":3,"title":["Case Report: Exertional rhabdomyolysis in a spin class participant with sickle cell trait"],"prefix":"10.12688","volume":"7","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3950-4014","authenticated-orcid":false,"given":"Teresa","family":"Longo","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5853-2497","authenticated-orcid":false,"given":"Matthew","family":"Shaines","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2560","published-online":{"date-parts":[[2019,7,1]]},"reference":[{"key":"ref-1","first-page":"789-93","article-title":"Exertional rhabdomyolysis after spinning: case series and review of the literature.","volume":"56","author":"A Ramme","year":"2016","journal-title":"J Sports Med Phys Fitness."},{"key":"ref-2","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/960363","article-title":"Creatine-kinase- and exercise-related muscle damage implications for muscle performance and recovery.","volume":"2012","author":"M Baird","year":"2012","journal-title":"J Nutr Metab."},{"key":"ref-3","doi-asserted-by":"publisher","first-page":"429-31","DOI":"10.1097\/JSM.0000000000000281","article-title":"Increasing Incidence and Unique Clinical Characteristics of Spinning-Induced Rhabdomyolysis.","volume":"26","author":"T Cutler","year":"2016","journal-title":"Clin J Sport Med."},{"key":"ref-4","doi-asserted-by":"publisher","first-page":"62-72","DOI":"10.1056\/NEJMra0801327","article-title":"Rhabdomyolysis and acute kidney injury.","volume":"361","author":"X Bosch","year":"2009","journal-title":"N Engl J Med."},{"key":"ref-5","doi-asserted-by":"publisher","first-page":"1532-6","DOI":"10.4045\/tidsskr.15.1207","article-title":"An increase in the number of admitted patients with exercise-induced rhabdomyolysis.","volume":"136","author":"C Aalborg","year":"2016","journal-title":"Tidsskr Nor Legeforen."},{"key":"ref-6","doi-asserted-by":"publisher","first-page":"435-442","DOI":"10.1056\/NEJMoa1516257","article-title":"Sickle Cell Trait, Rhabdomyolysis, and Mortality among U.S. Army Soldiers.","volume":"375","author":"D Nelson","year":"2016","journal-title":"N Engl J Med."},{"key":"ref-7","first-page":"67-71","article-title":"Compartment syndrome and fatal rhabdomyolysis in sickle cell trait.","volume":"104","author":"H Dincer","year":"2005","journal-title":"WMJ."},{"key":"ref-8","doi-asserted-by":"publisher","first-page":"1062-8","DOI":"10.1111\/imj.13168","article-title":"Spinning: an arising cause of rhabdomyolysis in young females.","volume":"46","author":"Y Kim","year":"2016","journal-title":"Intern Med J."},{"key":"ref-9","doi-asserted-by":"publisher","first-page":"484-487","DOI":"10.1016\/j.amjmed.2016.11.004","article-title":"Freebie Rhabdomyolysis: A Public Health Concern. Spin Class-Induced Rhabdomyolysis.","volume":"130","author":"M Brogan","year":"2017","journal-title":"Am J Med."},{"key":"ref-10","article-title":"Creatine Kinase: How Much is Too Much?","author":"J Kenny","year":"2010","journal-title":"The NYU Langone Online Journal of Medicine."},{"key":"ref-11","first-page":"704-710","article-title":"Using qualitative and quantitative strategies to evaluate knowledge and perceptions about sickle cell disease and sickle cell trait.","volume":"98","author":"M Treadwell","year":"2006","journal-title":"J Natl Med Assoc."},{"key":"ref-12","doi-asserted-by":"publisher","first-page":"5502","DOI":"10.4081\/hr.2014.5502","article-title":"Exertional sickling: questions and controversy.","volume":"6","author":"M Blinder","year":"2014","journal-title":"Hematol Rep."},{"key":"ref-13","doi-asserted-by":"publisher","first-page":"1292-1300","DOI":"10.1007\/s10897-017-0107-6","article-title":"Perspectives and Practices of Athletic Trainers and Team Physicians Implementing the 2010 NCAA Sickle Cell Trait Screening Policy.","volume":"26","author":"M McDonald","year":"2017","journal-title":"J Genet Couns."}],"container-title":["F1000Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/f1000research.com\/articles\/7-1742\/v2\/xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/f1000research.com\/articles\/7-1742\/v2\/pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/f1000research.com\/articles\/7-1742\/v2\/iparadigms","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,7,24]],"date-time":"2019-07-24T11:40:13Z","timestamp":1563968413000},"score":1,"resource":{"primary":{"URL":"https:\/\/f1000research.com\/articles\/7-1742\/v2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,7,1]]},"references-count":13,"URL":"https:\/\/doi.org\/10.12688\/f1000research.16326.2","relation":{"has-review":[{"id-type":"doi","id":"10.5256\/f1000research.21239.r50613","asserted-by":"subject"},{"id-type":"doi","id":"10.5256\/f1000research.21239.r50612","asserted-by":"subject"},{"id-type":"doi","id":"10.5256\/f1000research.21239.r50613","asserted-by":"object"},{"id-type":"doi","id":"10.5256\/f1000research.21239.r50612","asserted-by":"object"}]},"ISSN":["2046-1402"],"issn-type":[{"value":"2046-1402","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,7,1]]},"assertion":[{"value":"Indexed","URL":"https:\/\/f1000research.com\/articles\/7-1742\/v2#article-reports","order":0,"name":"referee-status","label":"Referee status","group":{"name":"current-referee-status","label":"Current Referee Status"}},{"value":"10.5256\/f1000research.21239.r50613, Gregory Kato, Pittsburgh Heart, Lung, Blood and Vascular Medicine Institute, University of Pittsburgh, Pittsburgh, PA, USA, 16 Jul 2019, version 2, indexed","URL":"https:\/\/f1000research.com\/articles\/7-1742\/v2#referee-response-50613","order":0,"name":"referee-response-50613","label":"Referee Report","group":{"name":"article-reports","label":"Article Reports"}},{"value":"10.5256\/f1000research.21239.r50612, Nyamkhishig Sambuughin, The Henry M. 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