{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T12:32:56Z","timestamp":1777984376434,"version":"3.51.4"},"update-to":[{"DOI":"10.12688\/f1000research.168964.1","type":"new_version","label":"New version","source":"publisher","updated":{"date-parts":[[2026,3,19]],"date-time":"2026-03-19T00:00:00Z","timestamp":1773878400000}}],"reference-count":28,"publisher":"F1000 Research Ltd","license":[{"start":{"date-parts":[[2026,3,19]],"date-time":"2026-03-19T00:00:00Z","timestamp":1773878400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"YARSI University","award":["1365\/REK\/PN.00\/VII\/2024"],"award-info":[{"award-number":["1365\/REK\/PN.00\/VII\/2024"]}]}],"content-domain":{"domain":["f1000research.com"],"crossmark-restriction":false},"short-container-title":["F1000Res"],"abstract":"<ns3:p>Background Major Depressive Disorder (MDD) can occur in patients with tuberculosis. The purpose of this research was to develop an early detection system for MDD and conduct an accuracy test. Methods The MOODMIND application uses Natural Language Processing (NLP) with sentiment analysis techniques. MOODMIND offers both speech and text options and is available in Indonesian\/English. The screening results were compared with physician clinical interview. Single blinding was used so that doctor was unaware of the application test. Results The app asks open- and closed-ended questions for MDD identification based on the DSM-5. The test results were divided into non-depressive (none or at-risk) and suspected depression groups. Among the 21 subjects, MOODMIND showed 67% (95% CI: 9.4\u201399.2%) sensitivity and 100% (95% CI: 81.5\u2013100%) specificity. Conclusions MOODMIND demonstrated accuracy results in pilot study but required advanced research with more sample and diverse settings. Ease is advantageous because the steps are simple, but it can be improved by adding words related to depression in the lexicon adjustment for increasing diagnostic performance.<\/ns3:p>","DOI":"10.12688\/f1000research.168964.2","type":"journal-article","created":{"date-parts":[[2026,3,19]],"date-time":"2026-03-19T10:34:09Z","timestamp":1773916449000},"page":"1079","update-policy":"https:\/\/doi.org\/10.12688\/f1000research.crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["MOODMIND: A Pilot Feasibility Study of Artificial Intelligence for Major Depressive Disorder Screening in Tuberculosis Patients"],"prefix":"10.12688","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8081-9902","authenticated-orcid":false,"given":"Erlina","family":"Wijayanti","sequence":"first","affiliation":[{"name":"Family Medicine Primary Care Study Program, Faculty of Medicine Central Jakarta Jakarta Yarsi University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ammar","family":"Abror","sequence":"additional","affiliation":[{"name":"Faculty of Information Technology Jakarta Yarsi University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4610-3350","authenticated-orcid":false,"given":"Ummi Azizah","family":"Rachmawati","sequence":"additional","affiliation":[{"name":"Faculty of Information Technology Jakarta Yarsi University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Citra Fitri","family":"Agustina","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Faculty of Medicine Jakarta Yarsi University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Helwiah","family":"Umniyati","sequence":"additional","affiliation":[{"name":"Faculty of Dentistry Jakarta YARSI University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Diana Batara","family":"Munti","sequence":"additional","affiliation":[{"name":"Family Medicine Primary Care Study Program, Faculty of Medicine Central Jakarta Jakarta Yarsi University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Exir Najib","family":"Rahmat","sequence":"additional","affiliation":[{"name":"Faculty of Medicine Jakarta Yarsi University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Athoillah Ahkam","family":"Diansyah","sequence":"additional","affiliation":[{"name":"Faculty of Medicine Jakarta Yarsi University"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2560","published-online":{"date-parts":[[2026,3,19]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"e0227472-e0227413","DOI":"10.1371\/journal.pone.0227472","article-title":"Association between tuberculosis and depression on negative outcomes of tuberculosis treatment: A systematic review and meta-analysis.","volume":"15","author":"P Ruiz-Grosso","year":"2020","journal-title":"PLoS One."},{"key":"ref2","doi-asserted-by":"publisher","first-page":"852-861","DOI":"10.5588\/ijtld.16.0584","article-title":"Addressing the tuberculosis\u2013depression syndemic to end the tuberculosis epidemic.","volume":"21","author":"A Sweetland","year":"2017","journal-title":"Int. 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Espinola, McMaster University, Hamilton, 13 Jan 2026, version 1, 2 approved with reservations, 1 not approved","URL":"https:\/\/f1000research.com\/articles\/14-1079\/v1#referee-response-435547","order":1,"name":"referee-response-435547","label":"Referee Report","group":{"name":"article-reports","label":"Article Reports"}},{"value":"10.5256\/f1000research.186213.r447567, Hayder Al-Hindy, College of Pharmacology, University of Babylon (Ringgold ID: 125654), Babylon Governorate, Babylon Governorate, 29 Jan 2026, version 1, 2 approved with reservations, 1 not approved","URL":"https:\/\/f1000research.com\/articles\/14-1079\/v1#referee-response-447567","order":2,"name":"referee-response-447567","label":"Referee Report","group":{"name":"article-reports","label":"Article Reports"}},{"value":"This research was supported by a grant from YARSI University (number 1365\/REK\/PN.00\/VII\/2024). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.","order":3,"name":"grant-information","label":"Grant Information"},{"value":"This is an open access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.","order":0,"name":"copyright-info","label":"Copyright"}]}}