{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T09:01:20Z","timestamp":1780390880190,"version":"3.54.1"},"update-to":[{"DOI":"10.12688\/f1000research.179345.1","type":"new_version","label":"New version","source":"publisher","updated":{"date-parts":[[2026,5,25]],"date-time":"2026-05-25T00:00:00Z","timestamp":1779667200000}}],"reference-count":12,"publisher":"F1000 Research Ltd","license":[{"start":{"date-parts":[[2026,5,25]],"date-time":"2026-05-25T00:00:00Z","timestamp":1779667200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["f1000research.com"],"crossmark-restriction":false},"short-container-title":["F1000Res"],"abstract":"<ns3:p>Background Partial edentulism in the posterior maxilla is frequently complicated by alveolar bone resorption and maxillary sinus pneumatization, limiting implant placement and negatively affecting oral health\u2013related quality of life (OHRQoL). Minimally invasive sinus augmentation techniques, such as CAS KIT\u2013assisted indirect sinus elevation, aim to reduce surgical morbidity; however, evidence regarding patient-reported outcomes and quality of life following such interventions remains limited. Objective To evaluate oral health\u2013related quality of life and patient-reported outcomes following implant rehabilitation using CAS KIT\u2013assisted indirect maxillary sinus augmentation. Materials and Methods This longitudinal observational study included 34 patients who underwent CAS KIT\u2013assisted transcrestal sinus augmentation with implant placement in the posterior maxilla. Postoperative recovery and satisfaction were assessed using the HRQOLquestionnaire over seven postoperative days. OHRQoL was evaluated using the OHIP-14 questionnaire at baseline and one month after prosthetic rehabilitation. Data were analyzed using repeated measures ANOVA with a significance level set at p\u00a0&lt;\u00a00.05. Results HRQOLscores showed a statistically significant improvement over the seven-day postoperative period (p\u00a0&lt;\u00a00.001), with stabilization observed from Day 5 onward. OHIP-14 scores demonstrated a highly significant reduction from baseline to post-intervention assessment (p\u00a0&lt;\u00a00.001), indicating marked improvement in OHRQoL across all participants. Conclusion CAS KIT\u2013assisted indirect sinus augmentation followed by implant rehabilitation results in rapid postoperative recovery and significant improvement in patient-reported outcomes, supporting its role as a predictable and patient-centered treatment modality for posterior maxillary rehabilitation.<\/ns3:p>","DOI":"10.12688\/f1000research.179345.2","type":"journal-article","created":{"date-parts":[[2026,5,25]],"date-time":"2026-05-25T14:09:08Z","timestamp":1779718148000},"page":"579","update-policy":"https:\/\/doi.org\/10.12688\/f1000research.crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Oral Health\u2013Related Quality of Life and Patient-Reported Outcomes After Implant Rehabilitation Using CAS Kit\u2013Assisted Indirect Maxillary Sinus Augmentation: A Longitudinal Observational Study"],"prefix":"10.12688","volume":"15","author":[{"given":"Sanath","family":"Kumar Shetty","sequence":"first","affiliation":[{"name":"PROSTHODONTICS Mangaluru Karnataka Yenepoya (Deemed to be University) Dental College"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-3233-975X","authenticated-orcid":false,"given":"Mallikarjuna","family":"Ragher","sequence":"additional","affiliation":[{"name":"PROSTHODONTICS Mangalore Karnataka 575018 Yenepoya (Deemed to be University) Dental College"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2538-2012","authenticated-orcid":false,"given":"Rajesh","family":"Shetty","sequence":"additional","affiliation":[{"name":"PROSTHODONTICS Mangalore Karnataka 575018 Yenepoya (Deemed to be University) Dental College"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Savitha","family":"Dandekeri","sequence":"additional","affiliation":[{"name":"PROSTHODONTICS Mangalore Karnataka 575018 Yenepoya (Deemed to be University) Dental College"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sunaina","family":"M","sequence":"additional","affiliation":[{"name":"PROSTHODONTICS Mangalore Karnataka 575018 Yenepoya (Deemed to be University) Dental College"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nafiya","family":"Abdul Aziz","sequence":"additional","affiliation":[{"name":"PROSTHODONTICS Mangalore Karnataka 575018 Yenepoya (Deemed to be University) Dental College"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2560","published-online":{"date-parts":[[2026,5,25]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1186\/s40729-024-00555-w","article-title":"Effects of various prosthetic methods for patients with Kennedy Class I partial edentulism on oral hypofunction, subjective symptoms, and oral health-related quality of life.","volume":"10","author":"D Morinaga","year":"2024 Jun 27","journal-title":"Int. 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Res."},{"key":"ref6","doi-asserted-by":"crossref","first-page":"2583","DOI":"10.3390\/ijerph20032583","article-title":"Clinical and radiological evaluation of a self-condensing bone implant in one-stage sinus augmentation: A 3-year follow-up retrospective study.","volume":"20","author":"L Comuzzi","year":"2023 Jan 31","journal-title":"Int. J. Environ. Res. Public Health."},{"key":"ref7","doi-asserted-by":"crossref","first-page":"88","DOI":"10.4103\/1735-3327.359325","article-title":"Comparison of clinical and radiological outcomes using crestal approach sinus kit and piezoelectric surgery for sinus membrane elevation: A prospective clinical trial.","volume":"19","author":"A Mamidi","year":"2022 Oct 20","journal-title":"Dent. Res. 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Dent."},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.5281\/zenodo.19274689","author":"M Ragher","year":"2026","journal-title":"Zenodo."}],"container-title":["F1000Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/f1000research.com\/articles\/15-579\/v2\/xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/f1000research.com\/articles\/15-579\/v2\/pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/f1000research.com\/articles\/15-579\/v2\/iparadigms","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T08:04:07Z","timestamp":1780387447000},"score":1,"resource":{"primary":{"URL":"https:\/\/f1000research.com\/articles\/15-579\/v2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,25]]},"references-count":12,"URL":"https:\/\/doi.org\/10.12688\/f1000research.179345.2","relation":{"has-version":[{"id-type":"doi","id":"10.12688\/f1000research.179345.1","asserted-by":"subject"}],"has-review":[{"id-type":"doi","id":"10.5256\/f1000research.201414.r488327","asserted-by":"subject"},{"id-type":"doi","id":"10.5256\/f1000research.201414.r488465","asserted-by":"subject"},{"id-type":"doi","id":"10.5256\/f1000research.201414.r488327","asserted-by":"object"},{"id-type":"doi","id":"10.5256\/f1000research.201414.r488465","asserted-by":"object"}]},"ISSN":["2046-1402"],"issn-type":[{"value":"2046-1402","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5,25]]},"assertion":[{"value":"Indexed","URL":"https:\/\/f1000research.com\/articles\/15-579\/v2#article-reports","order":0,"name":"referee-status","label":"Referee status","group":{"name":"current-referee-status","label":"Current Referee Status"}},{"value":"10.5256\/f1000research.201414.r488327, Pankaj Dhawan, Manav Rachna International Institute Of Research And Studies, Faridabad, Haryana, 02 Jun 2026, version 2, indexed","URL":"https:\/\/f1000research.com\/articles\/15-579\/v2#referee-response-488327","order":0,"name":"referee-response-488327","label":"Referee Report","group":{"name":"article-reports","label":"Article Reports"}},{"value":"10.5256\/f1000research.197850.r477155, Anupama Aradya, JSS Dental College and Hospital, JSS Academy of Higher Education and Research, Mysuru, Karnataka, 08 May 2026, version 1, 1 approved, 1 approved with reservations","URL":"https:\/\/f1000research.com\/articles\/15-579\/v1#referee-response-477155","order":1,"name":"referee-response-477155","label":"Referee Report","group":{"name":"article-reports","label":"Article Reports"}},{"value":"<b>MALLIKARJUNA RAGHER<\/b>; \n<i>Posted: 11 May 2026<\/i>; \n<b>Reviewer Comment 1<\/b> \n<b>Comment:<\/b> The manuscript addresses a clinically relevant topic by evaluating patient-reported outcomes following CAS KIT\u2013assisted indirect sinus augmentation and implant rehabilitation. The emphasis on oral health\u2013related quality of life adds value to the existing literature. \n<b>Response:<\/b> We thank the reviewer for the positive appreciation of our work and for recognizing the clinical relevance of evaluating patient-reported oral health\u2013related quality-of-life outcomes following CAS KIT\u2013assisted indirect sinus augmentation and implant rehabilitation.  \n<b>Reviewer Comment 2<\/b> \n<b>Comment:<\/b> The introduction is comprehensive; however, the rationale for selecting a cross-sectional design should be explained more clearly, particularly considering that baseline and postoperative assessments were performed over time. \n<b>Response:<\/b> We agree that the study design was incorrectly described as cross-sectional in the original manuscript. Since the same participants were evaluated prospectively across multiple postoperative time intervals, the study is more appropriately classified as a prospective longitudinal observational study. The terminology has been revised throughout the manuscript to accurately reflect the study design.  \n<b>Revised manuscript text:<\/b> This study was designed as a prospective longitudinal observational study  &nbsp;\n<b>Reviewer Comment 3<\/b>  \n<b>Comment:<\/b> The methodology section requires clarification regarding the timing of OHIP-14 administration. Please specify whether the baseline questionnaire was administered before surgery or retrospectively after treatment completion. \n<b>Response:<\/b> The methodology section has been clarified to specify the timing of OHIP-14 administration. The baseline OHIP-14 questionnaire was administered preoperatively before the surgical procedure, and subsequent assessments were recorded during the postoperative follow-up period. \n<b>Revised manuscript text:<\/b> The baseline OHIP-14 questionnaire was administered preoperatively before the surgical procedure, and postoperative assessments were recorded during follow-up visits.  \n<b>Reviewer Comment 4<\/b> \n<b>Comment:<\/b> The discussion section is well supported with relevant literature, but additional comparison with recent studies evaluating minimally invasive sinus augmentation techniques would strengthen the manuscript further. \n<b>Response:<\/b> Additional recent studies related to minimally invasive transcrestal sinus augmentation techniques and CAS KIT-assisted procedures have now been incorporated into the Discussion section to better contextualize the present findings with the existing literature.   \n<b>Reviewer Comment 5<\/b> \n<b>Comment:<\/b> Minor grammatical and formatting inconsistencies are present throughout the manuscript (e.g., spacing, punctuation, and author affiliation superscripts) and should be carefully revised during proofreading. \n<b>Response:<\/b> The manuscript has been carefully revised for grammatical accuracy, formatting consistency, spacing, punctuation, and author affiliation formatting throughout the text.","URL":"https:\/\/f1000research.com\/articles\/15-579\/v2#referee-comment-16181","order":2,"name":"referee-comment-16181","label":"Referee Comment","group":{"name":"article-reports","label":"Article Reports"}},{"value":"10.5256\/f1000research.201414.r488465, Praveen Jodalli, Manipal University, Manipal, 02 Jun 2026, version 2, indexed","URL":"https:\/\/f1000research.com\/articles\/15-579\/v2#referee-response-488465","order":3,"name":"referee-response-488465","label":"Referee Report","group":{"name":"article-reports","label":"Article Reports"}},{"value":"The author(s) declared that no grants were involved in supporting this work","order":4,"name":"grant-information","label":"Grant Information"},{"value":"This is an open access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.","order":0,"name":"copyright-info","label":"Copyright"}]}}