{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T12:48:19Z","timestamp":1791895699218,"version":"4.3.4"},"reference-count":21,"publisher":"F1000 Research Ltd","license":[{"start":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T00:00:00Z","timestamp":1782777600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["f1000research.com"],"crossmark-restriction":false},"short-container-title":["F1000Res"],"abstract":"<ns3:p>Background Shift workers face elevated cardiovascular disease risk. Radiographers represent a unique occupational group exposed to both low-level ionizing radiation and chronic night shift work \u2014 each independently associated with subclinical vascular disease \u2014 yet no synthesis exists on vascular function in this population. Objective To systematically identify and narratively synthesize evidence on associations between night shift work and objective vascular parameters \u2014 including CIMT, PWV, augmentation index, reactive hyperaemia index, and cerebrovascular white matter integrity \u2014 and assess applicability to radiographers. Methods A systematic search of Medline, Embase, Web of Science, Scopus, and CINAHL was conducted per PRISMA 2020. Eligible studies were primary observational studies reporting objective vascular outcomes in night shift workers. Risk of bias was assessed using JBI critical appraisal tools. Narrative synthesis with vote-counting was used; meta-analysis was not feasible due to heterogeneity. Results Ten studies from 2,257 records met the inclusion criteria across five vascular outcome domains. Cumulative night shift exposure was associated with increased arterial stiffness (PWV +1.29\u00a0m\/s over 3\u00a0years) and reduced endothelial function (RHI \u22120.054). Associations were frequently attenuated to non-significance after covariate adjustment, and CIMT findings were directionally inconsistent. Poor sleep quality independently predicted higher CIMT in healthcare workers. Former shift workers showed persistent cerebrovascular white matter changes. Conclusion Current evidence suggests possible associations between night shift work and arterial stiffness, though findings for other vascular outcomes remain inconsistent. No primary data exist for radiographers. The hypothesis of synergistic vascular injury from combined radiation and circadian disruption is biologically plausible but requires direct investigation through longitudinal, occupation-specific studies with standardized vascular outcome measures. Study Registration The review was developed and recorded following the PRISMA guidelines and has been registered with PROSPERO (CRD420261378070) on 24 April 2026.<\/ns3:p>","DOI":"10.12688\/f1000research.182990.1","type":"journal-article","created":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T08:09:10Z","timestamp":1782806950000},"page":"1032","update-policy":"https:\/\/doi.org\/10.12688\/f1000research.crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Night Shift Work and Vascular Function Parameters: A Systematic Review of Occupational and Healthcare Evidence with Implications for Radiographers"],"prefix":"10.12688","volume":"15","author":[{"given":"Suneet","family":"Paulson","sequence":"first","affiliation":[{"name":"Department of Medical Imaging Technology Manipal Karnataka 576104 Manipal Academy of Higher Education"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9345-9790","authenticated-orcid":false,"given":"Suresh","family":"Sukumar","sequence":"additional","affiliation":[{"name":"Department of Medical Imaging Technology Manipal Karnataka 576104 Manipal Academy of Higher Education"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6267-7266","authenticated-orcid":false,"given":"Poovitha","family":"Shruthi Paramshiva","sequence":"additional","affiliation":[{"name":"Division of Yoga Manipal Karnataka 576104 Manipal Academy of Higher Education"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3486-8740","authenticated-orcid":false,"given":"Rajagopal","family":"Kadavigere","sequence":"additional","affiliation":[{"name":"Department of Radio Diagnosis & Medical Imaging Manipal Karnataka 576104 Manipal Academy of Higher Education"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5963-3230","authenticated-orcid":false,"given":"Winniecia","family":"Dkhar","sequence":"additional","affiliation":[{"name":"Department of Medical Imaging Technology Manipal Karnataka 576104 Manipal Academy of Higher Education"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-0438-4339","authenticated-orcid":false,"given":"Eswaran","family":"TPM","sequence":"additional","affiliation":[{"name":"Department of Physiotherapy Manipal Karnataka 576104 Manipal Academy of Higher Education"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nitika C.","family":"Panakkal","sequence":"additional","affiliation":[{"name":"Department of Medical Imaging Technology Manipal Karnataka 576104 Manipal Academy of Higher Education"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2910-5338","authenticated-orcid":false,"given":"Abhimanyu","family":"Pradhan","sequence":"additional","affiliation":[{"name":"Department of Medical Imaging Technology Manipal Karnataka 576104 Manipal Academy of Higher Education"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5746-1682","authenticated-orcid":false,"given":"Vaishali","family":"K","sequence":"additional","affiliation":[{"name":"Department of Physiotherapy Manipal Karnataka 576104 Manipal Academy of Higher Education"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Baskaran","family":"Chandrasekaran","sequence":"additional","affiliation":[{"name":"Department of Exercise and Sports Sciences Pune Maharashtra 412115 Symbiosis International University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dilip","family":"Shettigar","sequence":"additional","affiliation":[{"name":"Department of Medical Imaging Technology Manipal Karnataka 576104 Manipal Academy of Higher Education"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sathya","family":"Sabina Muthu","sequence":"additional","affiliation":[{"name":"Department of Medical Imaging Technology Manipal Karnataka 576104 Manipal Academy of Higher Education"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Koustubh","family":"Kamath","sequence":"additional","affiliation":[{"name":"Department of Medical Imaging Technology Manipal Karnataka 576104 Manipal Academy of Higher Education"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4421-038X","authenticated-orcid":false,"given":"Sneha","family":"Ravichandran","sequence":"additional","affiliation":[{"name":"Department of Medical Imaging Technology Manipal Karnataka 576104 Manipal Academy of Higher Education"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2560","published-online":{"date-parts":[[2026,6,30]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"11","DOI":"10.5334\/gh.1288","article-title":"The Heart of the World.","volume":"19","author":"M Cesare","year":"2024 Jan 25","journal-title":"Glob. 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