{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T05:09:38Z","timestamp":1772168978087,"version":"3.50.1"},"reference-count":8,"publisher":"F1000 Research Ltd","license":[{"start":{"date-parts":[[2019,5,15]],"date-time":"2019-05-15T00:00:00Z","timestamp":1557878400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["f1000research.com"],"crossmark-restriction":false},"short-container-title":["F1000Res"],"abstract":"<ns4:p>Heparin induced thrombocytopenia (HIT) is a rare but potentially life threatening \u00a0adverse drug reaction. We report an unusual case of concomitant subacute coronary stent and femoral artery thrombosis secondary to HIT. In the current era of extensive growth of heparin use and percutaneous coronary interventions, it\u2019s important for clinicians to remember that such complication might occur and should be prevented.<\/ns4:p>","DOI":"10.12688\/f1000research.19041.1","type":"journal-article","created":{"date-parts":[[2019,5,15]],"date-time":"2019-05-15T11:10:28Z","timestamp":1557918628000},"page":"667","update-policy":"https:\/\/doi.org\/10.12688\/f1000research.crossmark-policy","source":"Crossref","is-referenced-by-count":5,"title":["Case Report: Concomitant coronary stent and femoral artery thrombosis in the setting of heparin-induced thrombocytopenia"],"prefix":"10.12688","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5457-3555","authenticated-orcid":false,"given":"Mejdi","family":"Ben Messaoud","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mezri","family":"Maatouk","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohamed Mehdi","family":"Boussaada","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4349-4544","authenticated-orcid":false,"given":"Marouane","family":"Mahjoub","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Walid","family":"Mnari","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Habib","family":"Gamra","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2560","published-online":{"date-parts":[[2019,5,15]]},"reference":[{"key":"ref-1","doi-asserted-by":"publisher","first-page":"2710-5","DOI":"10.1182\/blood-2005-04-1546","article-title":"Risk for heparin-induced thrombocytopenia with unfractionated and low-molecular-weight heparin thromboprophylaxis: a meta-analysis.","volume":"106","author":"N Martel","year":"2005","journal-title":"Blood."},{"key":"ref-2","doi-asserted-by":"publisher","first-page":"646-9","DOI":"10.4070\/kcj.2012.42.9.646","article-title":"Acute Stent Thrombosis and Heparin Induced Thrombocytopenia in a Patient With ST-Segment Elevation Myocardial Infarction.","volume":"42","author":"H Shin","year":"2012","journal-title":"Korean Circ J."},{"key":"ref-3","doi-asserted-by":"publisher","first-page":"145-149","DOI":"10.1016\/j.jccase.2016.12.013","article-title":"A case of heparin-induced thrombocytopenia with subacute stent thrombosis, multiple cerebral infarction, and acute limb ischemia.","volume":"15","author":"H Suzuki","year":"2017","journal-title":"J Cardiol Cases."},{"key":"ref-4","doi-asserted-by":"publisher","first-page":"408-14","DOI":"10.1182\/asheducation-2006.1.408","article-title":"Think of HIT.","author":"T Warkentin","year":"2006","journal-title":"Hematology Am Soc Hematol Educ Program."},{"key":"ref-5","doi-asserted-by":"publisher","first-page":"252-61","DOI":"10.1056\/NEJMcp1411910","article-title":"CLINICAL PRACTICE. Heparin-Induced Thrombocytopenia.","volume":"373","author":"A Greinacher","year":"2015","journal-title":"N Engl J Med."},{"key":"ref-6","doi-asserted-by":"publisher","first-page":"1104-1113","DOI":"10.1182\/blood-2017-04-778993","article-title":"Direct oral anticoagulants for treatment of HIT: update of Hamilton experience and literature review.","volume":"130","author":"T Warkentin","year":"2017","journal-title":"Blood."},{"key":"ref-7","doi-asserted-by":"publisher","first-page":"3360-3392","DOI":"10.1182\/bloodadvances.2018024489","article-title":"American Society of Hematology 2018 guidelines for management of venous thromboembolism: heparin-induced thrombocytopenia.","volume":"2","author":"A Cuker","year":"2018","journal-title":"Blood Adv."},{"key":"ref-8","doi-asserted-by":"publisher","first-page":"2053-2064","DOI":"10.1056\/NEJMra1606915","article-title":"Acute Myocardial Infarction.","volume":"376","author":"J Anderson","year":"2017","journal-title":"N Engl J Med."}],"container-title":["F1000Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/f1000research.com\/articles\/8-667\/v1\/xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/f1000research.com\/articles\/8-667\/v1\/pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/f1000research.com\/articles\/8-667\/v1\/iparadigms","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,2,24]],"date-time":"2020-02-24T13:01:20Z","timestamp":1582549280000},"score":1,"resource":{"primary":{"URL":"https:\/\/f1000research.com\/articles\/8-667\/v1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,5,15]]},"references-count":8,"URL":"https:\/\/doi.org\/10.12688\/f1000research.19041.1","relation":{"has-review":[{"id-type":"doi","id":"10.5256\/f1000research.20868.r48571","asserted-by":"subject"},{"id-type":"doi","id":"10.5256\/f1000research.20868.r49698","asserted-by":"subject"},{"id-type":"doi","id":"10.5256\/f1000research.20868.r48571","asserted-by":"object"},{"id-type":"doi","id":"10.5256\/f1000research.20868.r49698","asserted-by":"object"}]},"ISSN":["2046-1402"],"issn-type":[{"value":"2046-1402","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,5,15]]},"assertion":[{"value":"Indexed","URL":"https:\/\/f1000research.com\/articles\/8-667\/v1#article-reports","order":0,"name":"referee-status","label":"Referee status","group":{"name":"current-referee-status","label":"Current Referee Status"}},{"value":"10.5256\/f1000research.20868.r48571, Batric Popovic, Department of Cardiology, Centre Hospitalier Universitaire Brabois, Nancy, France, 04 Jun 2019, version 1, indexed","URL":"https:\/\/f1000research.com\/articles\/8-667\/v1#referee-response-48571","order":0,"name":"referee-response-48571","label":"Referee Report","group":{"name":"article-reports","label":"Article Reports"}},{"value":"10.5256\/f1000research.20868.r49698, Marouane Boukhris, Centre Hospitalier de l'Universit\u00e9 de Montr\u00e9al, Quebec, Canada, 04 Jul 2019, version 1, indexed","URL":"https:\/\/f1000research.com\/articles\/8-667\/v1#referee-response-49698","order":1,"name":"referee-response-49698","label":"Referee Report","group":{"name":"article-reports","label":"Article Reports"}},{"value":"The author(s) declared that no grants were involved in supporting this work","order":2,"name":"grant-information","label":"Grant Information"},{"value":"This is an open access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.","order":0,"name":"copyright-info","label":"Copyright"}]}}