{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T09:57:20Z","timestamp":1790848640128,"version":"4.1.0"},"reference-count":9,"publisher":"F1000 Research Ltd","license":[{"start":{"date-parts":[[2013,10,28]],"date-time":"2013-10-28T00:00:00Z","timestamp":1382918400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":["f1000research.com"],"crossmark-restriction":false},"short-container-title":["F1000Res"],"abstract":"<ns4:p>We report a case of a 2 year-old male patient who developed generalized hypertrichosis after 2 months of treatment with 5% minoxidil foam for alopecia areata. This report highlights the danger of prescribing\u00a0 topical minoxidil to young children and the need to correctly instruct caretakers about its administration.<\/ns4:p>","DOI":"10.12688\/f1000research.2-226.v1","type":"journal-article","created":{"date-parts":[[2013,10,28]],"date-time":"2013-10-28T08:32:46Z","timestamp":1382949166000},"page":"226","update-policy":"https:\/\/doi.org\/10.12688\/f1000research.crossmark-policy","source":"Crossref","is-referenced-by-count":20,"title":["Minoxidil induced hypertrichosis in a 2 year-old child"],"prefix":"10.12688","volume":"2","author":[{"given":"Ingrid","family":"Herskovitz","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joshua","family":"Freedman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonella","family":"Tosti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2560","published-online":{"date-parts":[[2013,10,28]]},"reference":[{"key":"ref-1","doi-asserted-by":"crossref","first-page":"365-8","DOI":"10.1177\/106002809002400404","article-title":"Drug-induced hypertrichosis: case report and review of the literature.","volume":"24","author":"L Miwa","year":"1990","journal-title":"DICP."},{"key":"ref-2","first-page":"527-8","article-title":"[Diffuse hypertrichosis caused by minoxidil in a 2-and-a-half-year-old child].","volume":"112","author":"G Lorette","year":"1985","journal-title":"Ann Dermatol Venereol."},{"key":"ref-3","doi-asserted-by":"crossref","first-page":"434-6","DOI":"10.1542\/peds.79.3.434","article-title":"Hypertrichosis and congenital anomalies associated with maternal use of minoxidil.","volume":"79","author":"S Kaler","year":"1987","journal-title":"Pediatrics."},{"key":"ref-4","first-page":"474-6","article-title":"[Cutaneous application of monoxidil during pregnancy: hairy infant].","volume":"50","author":"G Veyrac","year":"1995","journal-title":"Therapie."},{"key":"ref-5","doi-asserted-by":"publisher","first-page":"118-20","DOI":"10.1046\/j.1365-2133.1997.d01-1156.x","article-title":"Diffuse hypertrichosis during treatment with 5% topical minoxidil.","volume":"136","author":"A Peluso","year":"1997","journal-title":"Br J Dermatol."},{"key":"ref-6","doi-asserted-by":"publisher","first-page":"157-8","DOI":"10.1111\/j.1365-2230.1994.tb01147.x","article-title":"Generalized hypertrichosis after treatment with topical minoxidil.","volume":"19","author":"M Gonz\u00e1lez","year":"1994","journal-title":"Clin Exp Dermatol."},{"key":"ref-7","article-title":"Comprehensive dermatologic drug therapy.","author":"K Roy","year":"2013"},{"key":"ref-8","doi-asserted-by":"publisher","first-page":"101-2","DOI":"10.1159\/000096924","article-title":"Topical use of minoxidil in children and systemic side effects.","volume":"214","author":"S Georgala","year":"2007","journal-title":"Dermatology."},{"key":"ref-9","doi-asserted-by":"publisher","first-page":"CD004413","DOI":"10.1002\/14651858.CD004413.pub2","article-title":"Interventions for alopecia areata.","volume":"16","author":"F Delamere","year":"2008","journal-title":"Cochrane Database Syst Rev."}],"container-title":["F1000Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/f1000research.com\/articles\/2-226\/v1\/xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/f1000research.com\/articles\/2-226\/v1\/pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/f1000research.com\/articles\/2-226\/v1\/iparadigms","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,10]],"date-time":"2022-03-10T14:23:05Z","timestamp":1646922185000},"score":1,"resource":{"primary":{"URL":"https:\/\/f1000research.com\/articles\/2-226\/v1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,10,28]]},"references-count":9,"URL":"https:\/\/doi.org\/10.12688\/f1000research.2-226.v1","relation":{"has-review":[{"id-type":"doi","id":"10.5256\/f1000research.2444.r2221","asserted-by":"subject"},{"id-type":"doi","id":"10.5256\/f1000research.2444.r2220","asserted-by":"subject"},{"id-type":"doi","id":"10.5256\/f1000research.2444.r2221","asserted-by":"object"},{"id-type":"doi","id":"10.5256\/f1000research.2444.r2220","asserted-by":"object"}]},"ISSN":["2046-1402"],"issn-type":[{"value":"2046-1402","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,10,28]]},"assertion":[{"value":"Indexed","URL":"https:\/\/f1000research.com\/articles\/2-226\/v1#article-reports","order":0,"name":"referee-status","label":"Referee status","group":{"name":"current-referee-status","label":"Current Referee Status"}},{"value":"10.5256\/f1000research.2444.r2220, Mohamed Badawy Hassan Tawfik Abdel-Naser, Faculty of Medicine, Ain Shams University, Cairo, Egypt, 05 Nov 2013, version 1, indexed","URL":"https:\/\/f1000research.com\/articles\/2-226\/v1#referee-response-2220","order":0,"name":"referee-response-2220","label":"Referee Report","group":{"name":"article-reports","label":"Article Reports"}},{"value":"10.5256\/f1000research.2444.r2221, Johannes Steffen Kern, Department of Dermatology and Venereology, University Medical Center Freiburg, University of Freiburg, Freiburg, Germany, 11 Nov 2013, version 1, indexed","URL":"https:\/\/f1000research.com\/articles\/2-226\/v1#referee-response-2221","order":1,"name":"referee-response-2221","label":"Referee Report","group":{"name":"article-reports","label":"Article Reports"}},{"value":"The author(s) declared that no grants were involved in supporting this work","order":2,"name":"grant-information","label":"Grant Information"},{"value":"This is an open access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.Data associated with the article are available under the terms of the Creative Commons Zero \"No rights reserved\" data waiver (CC0 1.0 Public domain dedication).","order":0,"name":"copyright-info","label":"Copyright"}]}}