{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T05:09:21Z","timestamp":1772168961362,"version":"3.50.1"},"reference-count":7,"publisher":"F1000 Research Ltd","license":[{"start":{"date-parts":[[2019,11,5]],"date-time":"2019-11-05T00:00:00Z","timestamp":1572912000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["f1000research.com"],"crossmark-restriction":false},"short-container-title":["F1000Res"],"abstract":"<ns3:p>\n                    <ns3:bold>Background:<\/ns3:bold>\n                    Sarcoidosis is an inflammatory disease that affects multiple organs in the body, especially the lungs and lymph nodes. The coexistence of sarcoidosis and breast cancer has been reported, but the coexistence of both diseases in the same patient often leads to misdiagnosis.\n                  <\/ns3:p>\n                  <ns3:p>\n                    <ns3:bold>Case:<\/ns3:bold>\n                    We report a case of a 36-year-old woman who presented with concerns of a lump in her left breast along with pain and discharge from the nipple. On examination a 3-cm hard and tender mass was noted in the upper medial quadrant of the left breast with no palpable axillary lymph nodes.\n                  <\/ns3:p>\n                  <ns3:p>The patient was diagnosed with an infiltrating ductal cell carcinoma of the left breast with T2N0M1 Stage IV disease, due to positive mediastinal lymphadenopathy on positron emission tomography scan. The biopsy of mediastinal lymph nodes allowed us to diagnose sarcoidosis and correctly stage her disease as T2N0M0 Stage IIA breast cancer. The patient underwent lumpectomy followed by adjuvant chemo radiotherapy and hormonal therapy - corticosteroids given for sarcoidosis up to 1 year. The patient is doing well 18 months later without recurrence of disease.<\/ns3:p>\n                  <ns3:p>\n                    <ns3:bold>Conclusion:<\/ns3:bold>\n                    The simultaneous occurrence of both diseases in the same patient is the risk for misdiagnosis and mismanagement, therefore it is of utmost importance to correctly stage the disease with appropriate investigations and histologic confirmation prior to initiate the treatment for breast cancer.\n                  <\/ns3:p>","DOI":"10.12688\/f1000research.20825.1","type":"journal-article","created":{"date-parts":[[2019,11,5]],"date-time":"2019-11-05T10:20:27Z","timestamp":1572949227000},"page":"1853","update-policy":"https:\/\/doi.org\/10.12688\/f1000research.crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Case Report: Sarcoidosis in the lymph nodes of a breast cancer patient"],"prefix":"10.12688","volume":"8","author":[{"given":"Perwasha","family":"Kerio","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8256-2979","authenticated-orcid":false,"given":"Zain","family":"Abid","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masooma","family":"Abid","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Desaar","family":"Zehra","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ghulam","family":"Haider","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2560","published-online":{"date-parts":[[2019,11,5]]},"reference":[{"key":"ref-1","doi-asserted-by":"publisher","first-page":"394-424","DOI":"10.3322\/caac.21492","article-title":"Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries.","volume":"68","author":"F Bray","year":"2018","journal-title":"CA Cancer J Clin."},{"key":"ref-2","article-title":"SEER Cancer Statistics Review, 1975-2014.","author":"N Howlader","year":"2017"},{"key":"ref-3","doi-asserted-by":"publisher","first-page":"e1095","DOI":"10.1097\/MD.0000000000001095","article-title":"Evaluation of Mediastinal Lymph Nodes in Sarcoidosis, Sarcoid Reaction, and Malignant Lymph Nodes Using CT and FDG-PET\/CT.","volume":"94","author":"H Koo","year":"2015","journal-title":"Medicine (Baltimore)."},{"key":"ref-4","doi-asserted-by":"publisher","first-page":"134-6","DOI":"10.4103\/0973-1482.43148","article-title":"Pulmonary sarcoidosis simulating metastatic breast cancer.","volume":"4","author":"D Dragoumis","year":"2008","journal-title":"J Cancer Res Ther."},{"key":"ref-5","doi-asserted-by":"publisher","first-page":"396-398","DOI":"10.20892\/j.issn.2095-3941.2016.0038","article-title":"Sarcoidosis imitating breast cancer metastasis: a case report and literature review.","volume":"13","author":"T Kochoyan","year":"2016","journal-title":"Cancer Biol Med."},{"key":"ref-6","doi-asserted-by":"publisher","first-page":"71-4","DOI":"10.5152\/UCD.2015.2989","article-title":"Sarcoidosis mimicking metastatic breast cancer in a patient with early-stage breast cancer.","volume":"32","author":"M Alt\u0131nkaya","year":"2015","journal-title":"Ulus Cerrahi Derg."},{"key":"ref-7","doi-asserted-by":"publisher","first-page":"137-40","DOI":"10.1159\/000381324","article-title":"Breast Cancer and Sarcoidosis: Case Series and Review of the Literature.","volume":"10","author":"J Chen","year":"2015","journal-title":"Breast Care (Basel)."}],"container-title":["F1000Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/f1000research.com\/articles\/8-1853\/v1\/xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/f1000research.com\/articles\/8-1853\/v1\/pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/f1000research.com\/articles\/8-1853\/v1\/iparadigms","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,3,16]],"date-time":"2021-03-16T11:52:15Z","timestamp":1615895535000},"score":1,"resource":{"primary":{"URL":"https:\/\/f1000research.com\/articles\/8-1853\/v1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,11,5]]},"references-count":7,"URL":"https:\/\/doi.org\/10.12688\/f1000research.20825.1","relation":{"has-review":[{"id-type":"doi","id":"10.5256\/f1000research.22905.r56717","asserted-by":"subject"},{"id-type":"doi","id":"10.5256\/f1000research.22905.r80201","asserted-by":"subject"},{"id-type":"doi","id":"10.5256\/f1000research.22905.r80201","asserted-by":"object"},{"id-type":"doi","id":"10.5256\/f1000research.22905.r56717","asserted-by":"object"}]},"ISSN":["2046-1402"],"issn-type":[{"value":"2046-1402","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,11,5]]},"assertion":[{"value":"Indexed","URL":"https:\/\/f1000research.com\/articles\/8-1853\/v1#article-reports","order":0,"name":"referee-status","label":"Referee status","group":{"name":"current-referee-status","label":"Current Referee Status"}},{"value":"10.5256\/f1000research.22905.r56717, Jun Jiang, National Cancer Center\/National Clinical Research Center for Cancer\/Cancer Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China, 12 Jun 2020, version 1, indexed","URL":"https:\/\/f1000research.com\/articles\/8-1853\/v1#referee-response-56717","order":0,"name":"referee-response-56717","label":"Referee Report","group":{"name":"article-reports","label":"Article Reports"}},{"value":"10.5256\/f1000research.22905.r80201, Tim L Jansen, Department of Rheumatology, Expert Centre for Complex Gout, Viecuri Medical Centre, Venlo, The Netherlands, 16 Mar 2021, version 1, indexed","URL":"https:\/\/f1000research.com\/articles\/8-1853\/v1#referee-response-80201","order":1,"name":"referee-response-80201","label":"Referee Report","group":{"name":"article-reports","label":"Article Reports"}},{"value":"The author(s) declared that no grants were involved in supporting this work","order":2,"name":"grant-information","label":"Grant Information"},{"value":"This is an open access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.","order":0,"name":"copyright-info","label":"Copyright"}]}}