{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T02:51:02Z","timestamp":1787021462430,"version":"build-2736575974"},"reference-count":10,"publisher":"F1000 Research Ltd","license":[{"start":{"date-parts":[[2020,2,18]],"date-time":"2020-02-18T00:00:00Z","timestamp":1581984000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["f1000research.com"],"crossmark-restriction":false},"short-container-title":["F1000Res"],"abstract":"<ns3:p>Rheumatoid arthritis (RA) is a common autoimmune disease characterized by inflammation of small joints. Small synovial joints in the larynx can also become affected, and laryngeal involvement is seen in more than half of patients with RA. As most patients have subtle symptoms and indolent course, they are either misdiagnosed or undiagnosed. The acute worsening of cricoarytenoid arthritis can cause sudden upper airway obstruction and may require emergency intubation or tracheostomy. This life-threatening condition is described in only a handful of cases in the medical literature. Physicians should be aware of this rare but life-threatening consequence of RA. We present a case of sudden and severe upper airway obstruction secondary to laryngeal involvement in a patient with long-standing RA.<\/ns3:p>","DOI":"10.12688\/f1000research.22256.1","type":"journal-article","created":{"date-parts":[[2020,2,18]],"date-time":"2020-02-18T11:30:32Z","timestamp":1582025432000},"page":"119","update-policy":"https:\/\/doi.org\/10.12688\/f1000research.crossmark-policy","source":"Crossref","is-referenced-by-count":2,"title":["Case Report: Upper airway obstruction due to rheumatoid arthritis"],"prefix":"10.12688","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3075-946X","authenticated-orcid":false,"given":"Mohan","family":"Rudrappa","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laxmi","family":"Kokatnur","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sanket","family":"Shah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2560","published-online":{"date-parts":[[2020,2,18]]},"reference":[{"key":"ref-1","doi-asserted-by":"publisher","first-page":"1094-1108","DOI":"10.1016\/S0140-6736(10)60826-4","article-title":"Rheumatoid arthritis.","volume":"376","author":"D Scott","year":"2010","journal-title":"Lancet."},{"key":"ref-2","doi-asserted-by":"publisher","first-page":"753-755","DOI":"10.1016\/j.amjoto.2012.06.004","article-title":"Cricoarytenoid joint involvement in rheumatoid arthritis: 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status","group":{"name":"current-referee-status","label":"Current Referee Status"}},{"value":"10.5256\/f1000research.24550.r68830, Waiz Wasey, Family and Community Medicine, Southern Illinois University School of Medicine, Springfield, USA, 06 Aug 2020, version 1, indexed","URL":"https:\/\/f1000research.com\/articles\/9-119\/v1#referee-response-68830","order":0,"name":"referee-response-68830","label":"Referee Report","group":{"name":"article-reports","label":"Article Reports"}},{"value":"10.5256\/f1000research.24550.r88077, Manish Gupta, Department of ENT, Maharishi Markandeshwar Institute of Medical Sciences & Research, Ambala, Haryana, India, 23 Aug 2021, version 1, indexed","URL":"https:\/\/f1000research.com\/articles\/9-119\/v1#referee-response-88077","order":1,"name":"referee-response-88077","label":"Referee Report","group":{"name":"article-reports","label":"Article Reports"}},{"value":"The author(s) declared that no grants were involved in supporting this 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