{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,13]],"date-time":"2026-06-13T09:39:32Z","timestamp":1781343572611,"version":"3.54.1"},"reference-count":29,"publisher":"F1000 Research Ltd","license":[{"start":{"date-parts":[[2020,5,11]],"date-time":"2020-05-11T00:00:00Z","timestamp":1589155200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["f1000research.com"],"crossmark-restriction":false},"short-container-title":["F1000Res"],"abstract":"<ns4:p>Cholecystitis is one of the leading causes of emergency surgical interventions; the occurrence of metastases to the gallbladder is rare and has only been reported in the literature exceptionally. Metastatic breast cancer to the gallbladder is even less frequent; in fact, breast cancer usually metastasizes to bone, lung, lymph nodes, liver and brain. We report the case of an 83-year-old female patient with a previous history of breast surgery with axillary dissection in 1997, followed by adjuvant chemotherapy due to invasive ductal carcinoma of the left breast. The patient was admitted at the emergency department for sepsis and an episode of acute kidney failure, anuria and fever. Right-upper quadrant abdominal pain triggered by food intake and abdominal tenderness was also present, placing the diagnostic suspicion of biliary sepsis due to acute cholecystitis. The histological examination of the surgical specimen highlighted the presence of metastasis from an infiltrating ductal breast carcinoma with positive hormone receptors. We also report here the results of a review of the literature looking at articles describing cases of gallbladder metastasis from breast cancer.<\/ns4:p>","DOI":"10.12688\/f1000research.23469.1","type":"journal-article","created":{"date-parts":[[2020,5,11]],"date-time":"2020-05-11T05:40:08Z","timestamp":1589175608000},"page":"343","update-policy":"https:\/\/doi.org\/10.12688\/f1000research.crossmark-policy","source":"Crossref","is-referenced-by-count":10,"title":["Case Report: Metastatic breast cancer to the gallbladder"],"prefix":"10.12688","volume":"9","author":[{"given":"Giulia","family":"Missori","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2701-4387","authenticated-orcid":false,"given":"Francesco","family":"Serra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giorgia","family":"Prestigiacomo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea Aurelio","family":"Ricciardolo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucio","family":"Brugioni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8471-710X","authenticated-orcid":false,"given":"Roberta","family":"Gelmini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2560","published-online":{"date-parts":[[2020,5,11]]},"reference":[{"key":"ref-1","doi-asserted-by":"publisher","first-page":"4806-4809","DOI":"10.3748\/wjg.15.4806","article-title":"Metastasis to the gallbladder: a single-center experience of 20 cases in South Korea.","volume":"15","author":"W Yoon","year":"2009","journal-title":"World J Gastroenterol."},{"key":"ref-2","doi-asserted-by":"publisher","first-page":"350-358","DOI":"10.1080\/00365521.2019.1588363","article-title":"Incidental metastases and lymphoma of the gallbladder - 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DIMEC, Alma Mater Studiorum - University of Bologna, Bologna, Italy, 30 Jul 2020, version 1, indexed","URL":"https:\/\/f1000research.com\/articles\/9-343\/v1#referee-response-64929","order":0,"name":"referee-response-64929","label":"Referee Report","group":{"name":"article-reports","label":"Article Reports"}},{"value":"10.5256\/f1000research.25900.r72530, Francesco Fleres, Department of Human Pathology, University of Messina, Messina, Italy, 15 Oct 2020, version 1, indexed","URL":"https:\/\/f1000research.com\/articles\/9-343\/v1#referee-response-72530","order":1,"name":"referee-response-72530","label":"Referee Report","group":{"name":"article-reports","label":"Article Reports"}},{"value":"The author(s) declared that no grants were involved in supporting this work","order":2,"name":"grant-information","label":"Grant Information"},{"value":"This is an open access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.","order":0,"name":"copyright-info","label":"Copyright"}]}}