{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T05:09:41Z","timestamp":1772168981534,"version":"3.50.1"},"update-to":[{"DOI":"10.12688\/f1000research.25164.1","type":"new_version","label":"New version","source":"publisher","updated":{"date-parts":[[2021,2,23]],"date-time":"2021-02-23T00:00:00Z","timestamp":1614038400000}}],"reference-count":38,"publisher":"F1000 Research Ltd","license":[{"start":{"date-parts":[[2021,2,23]],"date-time":"2021-02-23T00:00:00Z","timestamp":1614038400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"publisher","award":["2.962.837"],"award-info":[{"award-number":["2.962.837"]}],"id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["f1000research.com"],"crossmark-restriction":false},"short-container-title":["F1000Res"],"abstract":"<ns3:p>\n                    <ns3:bold>Aims:<\/ns3:bold>\n                    This study aims to evaluate the additional effect of anodal transcranial direct current stimulation (a-tDCS) applied on dorsolateral pr\u00e9-frontal cortex on training postural balance with the use of video games in the aged.\n                  <\/ns3:p>\n                  <ns3:p>\n                    <ns3:bold>Methods:<\/ns3:bold>\n                    This is a blinded, randomized, controlled clinical trial protocol, with older people of both genders. Participants will be randomized into three training groups: Group 1 (videogame balance training), group 2 (videogame balance training associated with anodal tDCS), group 3 (videogame balance training associated with sham tDCS). The training will be carried out twice a week for four weeks, totaling eight sessions, and will be performed with the Nintendo Wii videogame console, using games that stimulate the postural balance associated with tDCS, with anode applied over the left dorsolateral prefrontal cortex and cathode on the contralateral supraorbital region at 2 mA for 20 minutes. The postural balance will be assessed using the Mini Test of the Balance Assessment System and posturography. Evaluations will be carried out before and after eight training sessions and 30 days after the end of treatment.\n                  <\/ns3:p>\n                  <ns3:p>\n                    <ns3:bold>Discussion:<\/ns3:bold>\n                    Some studies show favorable results from the use of video games in improving postural balance in older people; however, their effect does not remain long-term. TDCS associated with other therapies can potentiate and prolong the effects of these therapies owing to its ability to stimulate neurotrophins important for neurogenesis, facilitating tasks that require attention, and helping to consolidate learning and memory. The effect of the two associated techniques on balance has not yet been tested in this population.\n                  <\/ns3:p>\n                  <ns3:p>\n                    <ns3:bold>Registration:<\/ns3:bold>\n                    Brazilian Registry of Clinical Trials ID\n                    <ns3:ext-link xmlns:ns4=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" ns4:href=\"http:\/\/www.ensaiosclinicos.gov.br\/rg\/RBR-4shrx2\/\">U1111-1213-4266<\/ns3:ext-link>\n                    ; registered on 15 October 2018.\n                  <\/ns3:p>","DOI":"10.12688\/f1000research.25164.2","type":"journal-article","created":{"date-parts":[[2021,2,23]],"date-time":"2021-02-23T10:56:14Z","timestamp":1614077774000},"page":"1018","update-policy":"https:\/\/doi.org\/10.12688\/f1000research.crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Protocol for a controlled, randomized, blind, clinical trial to assess the effects of anodal transcranial direct current stimulation dorsolateral prefrontal cortex associated with balance training using games in the postural balance of older people"],"prefix":"10.12688","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5966-9022","authenticated-orcid":false,"given":"Andre Issao","family":"Kunitake","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8642-9814","authenticated-orcid":false,"given":"Jo\u00e3o Carlos Ferrari","family":"Corr\u00eaa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Klaine Silva","family":"Nascimento","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bianca Barioni Cardoso de","family":"Oliveira","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Natalia Maciel","family":"Muniz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Soraia Micaela","family":"Silva","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7321-6257","authenticated-orcid":false,"given":"Fernanda Ishida","family":"Corr\u00eaa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2560","published-online":{"date-parts":[[2021,2,23]]},"reference":[{"key":"ref-1","article-title":"Envelhecimento e Sa\u00fade da Pessoa idosa.","year":"2006"},{"key":"ref-2","article-title":"Aten\u00e7\u00e3o \u00e0 Sa\u00fade da Pessoa Idosa e Envelhecimento","author":"M da Sa\u00fade","year":"2010"},{"key":"ref-3","doi-asserted-by":"publisher","first-page":"517-33","DOI":"10.1093\/ptj\/77.5.517","article-title":"Postural perturbations: new insights for treatment of balance 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status","group":{"name":"current-referee-status","label":"Current Referee Status"}},{"value":"10.5256\/f1000research.27770.r71407, Fernando Zanela da Silva Ar\u00eaas, Center of Health Sciences, Discipline of Physical Therapy, Federal University of Esp\u00edrito Santo (UFES), Vit\u00f3ria, Brazil, 02 Nov 2020, version 1, indexed","URL":"https:\/\/f1000research.com\/articles\/9-1018\/v1#referee-response-71407","order":0,"name":"referee-response-71407","label":"Referee Report","group":{"name":"article-reports","label":"Article Reports"}},{"value":"10.5256\/f1000research.47058.r80073, Rodrigo Vit\u00f3rio, Department of Neurology, Oregon Health and Science University, Portland, OR, USA, 23 Feb 2021, version 2, indexed","URL":"https:\/\/f1000research.com\/articles\/9-1018\/v2#referee-response-80073","order":1,"name":"referee-response-80073","label":"Referee Report","group":{"name":"article-reports","label":"Article Reports"}},{"value":"This study is funded and supported by the Higher Education Personnel Improvement Coordination in conjunction with Nove de Julho University (Opinion number 2.962.837), Brazil, S\u00e3o Paulo.","order":2,"name":"grant-information","label":"Grant Information"},{"value":"This is an open access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.","order":0,"name":"copyright-info","label":"Copyright"}]}}