{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T05:08:56Z","timestamp":1772168936982,"version":"3.50.1"},"update-to":[{"DOI":"10.12688\/f1000research.26924.1","type":"new_version","label":"New version","source":"publisher","updated":{"date-parts":[[2022,5,3]],"date-time":"2022-05-03T00:00:00Z","timestamp":1651536000000}}],"reference-count":16,"publisher":"F1000 Research Ltd","license":[{"start":{"date-parts":[[2022,5,3]],"date-time":"2022-05-03T00:00:00Z","timestamp":1651536000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Centre Hospitalier R\u00e9gional d\u2019Orl\u00e9ans"}],"content-domain":{"domain":["f1000research.com"],"crossmark-restriction":false},"short-container-title":["F1000Res"],"abstract":"<ns5:p>Coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and has been a global public health concern. We report coinfection of SARS-CoV-2 and 2009 H1N1 Influenza strain in a French patient with pneumonia leading to acute respiratory distress syndrome. \u00a0The patient also had a medical history of pulmonary sarcoidosis with a restrictive ventilatory syndrome and obesity, which would be a supplementary risk to develop a poor outcomes. This case highlights the possible coinfection of two severe SARS-CoV-2 and influenza H1N1 viruses in comorbid patient, which presents a higher risk to extend the care duration. The overlapping clinical features of the two respiratory syndromes is a challenge, and awareness is required to recommend an early differential diagnosis and it\u2019s necessary to adopt the vigilant preventive measures and therapeutic strategies to prevent a deleterious impacts in patients with comorbid factors.<\/ns5:p>","DOI":"10.12688\/f1000research.26924.2","type":"journal-article","created":{"date-parts":[[2022,5,3]],"date-time":"2022-05-03T08:15:06Z","timestamp":1651565706000},"page":"1482","update-policy":"https:\/\/doi.org\/10.12688\/f1000research.crossmark-policy","source":"Crossref","is-referenced-by-count":2,"title":["Case Report: Co-infection with SARS-CoV-2 and influenza H1N1 in a patient with acute respiratory distress syndrome and a pulmonary 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status","group":{"name":"current-referee-status","label":"Current Referee Status"}},{"value":"10.5256\/f1000research.129014.r136555, Louise E. Lansbury, Division of Epidemiology and Public Health, University of Nottingham, Nottingham, UK, 03 May 2022, version 2, indexed","URL":"https:\/\/f1000research.com\/articles\/9-1482\/v2#referee-response-136555","order":0,"name":"referee-response-136555","label":"Referee Report","group":{"name":"article-reports","label":"Article Reports"}},{"value":"10.5256\/f1000research.29738.r86503, Khalid Sadki, Laboratory of Human Pathologies Biology, Faculty of Sciences, Mohammed V University, Rabat, Morocco, 20 Jul 2021, version 1, 1 approved, 1 approved with reservations","URL":"https:\/\/f1000research.com\/articles\/9-1482\/v1#referee-response-86503","order":1,"name":"referee-response-86503","label":"Referee Report","group":{"name":"article-reports","label":"Article Reports"}},{"value":"<b>lekbir BAALA<\/b>; \n<i>Posted: 24 Mar 2022<\/i>; I am Dr. BAALA, a co-author of this article,&nbsp;I thank Pr. SADKI for his review and I am pleased to respond to his comments:  \n<i>We didn't give more details of the molecular data used for the SARS-CoV-2 and H1N1 tests since we were limited by the number of words not to be exceeded in the article. However, we may include some Ct data for SARS-CoV2 to indirectly indicate viral load kinetics.  As Pr Sadki and Pr Lansbury (first reviewer) suggested regarding the phenotype of the patient, the fact that the co-infection by SARS-Cov-2 and H1N1 viruses occurred in a patient with a history of pulmonary sarcoidosis, we will give more notice to the role of this immunosuppression history and poor outcome in the discussion.<\/i>","URL":"https:\/\/f1000research.com\/articles\/9-1482\/v2#referee-comment-8002","order":2,"name":"referee-comment-8002","label":"Referee Comment","group":{"name":"article-reports","label":"Article Reports"}},{"value":"This study was supported by Centre Hospitalier R\u00e9gional d\u2019Orl\u00e9ans (CHRO).","order":3,"name":"grant-information","label":"Grant Information"},{"value":"This is an open access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.","order":0,"name":"copyright-info","label":"Copyright"}]}}