{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,30]],"date-time":"2026-03-30T19:31:36Z","timestamp":1774899096015,"version":"3.50.1"},"reference-count":21,"publisher":"F1000 Research Ltd","license":[{"start":{"date-parts":[[2014,1,29]],"date-time":"2014-01-29T00:00:00Z","timestamp":1390953600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":["f1000research.com"],"crossmark-restriction":false},"short-container-title":["F1000Res"],"abstract":"<ns4:p>Pancreatico-pericardial fistula is an extremely rare complication of chronic pancreatitis. We present a case of a 58-year-old man who presented with syncope. Transthoracic echocardiogram revealed a pericardial effusion with tamponade physiology. Pericardiocentesis and pericardial fluid analysis demonstrated a lipase level of 2321 U\/L. Subsequently, an endoscopic retrograde cholangiopancreatography (ERCP) was performed, confirming the presence of a pancreatico-pericardial fistula (PPF) from the distal body of the pancreas. A pancreatic duct stent was placed across the duct disruption on two separate occasions; however, despite stent placement, the patient continued to re-accumulate pericardial fluid and deteriorated. While rare, PPFs may complicate chronic pancreatitis, may not respond to pancreatic duct stenting and may portend a poor prognosis.<\/ns4:p>","DOI":"10.12688\/f1000research.3-31.v1","type":"journal-article","created":{"date-parts":[[2014,1,29]],"date-time":"2014-01-29T09:19:48Z","timestamp":1390987188000},"page":"31","update-policy":"https:\/\/doi.org\/10.12688\/f1000research.crossmark-policy","source":"Crossref","is-referenced-by-count":4,"title":["Pancreatico-pericardial fistula as a complication of chronic pancreatitis"],"prefix":"10.12688","volume":"3","author":[{"given":"Camille Anne","family":"Sommer","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C. Mel","family":"Wilcox","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2560","published-online":{"date-parts":[[2014,1,29]]},"reference":[{"key":"ref-1","doi-asserted-by":"publisher","first-page":"228-236","DOI":"10.1097\/00006676-198904000-00012","article-title":"Thoracic complications of pancreatitis.","volume":"4","author":"C Iacono","year":"1989","journal-title":"Pancreas."},{"key":"ref-2","doi-asserted-by":"publisher","first-page":"e152-e156","DOI":"10.1097\/MJT.0b013e3181f62947","article-title":"Mediastinal extension of pancreatic pseudocyst--a case with review of topic and management guidelines.","volume":"19","author":"A Ajmera","year":"2012","journal-title":"Am J Ther."},{"key":"ref-3","doi-asserted-by":"publisher","first-page":"734-738","DOI":"10.1007\/BF02806357","article-title":"A case of chronic pancreatitis complicated by massive pericardial and right pleural effusion.","volume":"28","author":"Y Imai","year":"1993","journal-title":"Gastroenterol Jpn."},{"key":"ref-4","doi-asserted-by":"publisher","first-page":"1279-82","DOI":"10.1097\/00042737-200211000-00020","article-title":"Cardiac compromise due to a pancreatic mediastinal pseudocyst.","volume":"14","author":"M Tan","year":"2002","journal-title":"Eur J Gastroenterol Hepatol."},{"key":"ref-5","doi-asserted-by":"publisher","first-page":"405-10","DOI":"10.1186\/1752-1947-2-180","article-title":"Mediastinal pseudocyst with pericardial effusion and dysphagia treated by endoscopic drainage.","volume":"7","author":"S Komtong","year":"2006","journal-title":"JOP."},{"key":"ref-6","first-page":"478-80","article-title":"Internal pancreatic fistula to the pericardium and pleura.","volume":"85","author":"E Davidson","year":"1979","journal-title":"Surgery."},{"key":"ref-7","first-page":"31-32","article-title":"Pancreatico-pericardial fistula: a rare complication of chronic pancreatitis.","volume":"23","author":"P Balasubramanian","year":"2004","journal-title":"Indian J Gastroenterol."},{"key":"ref-8","doi-asserted-by":"publisher","first-page":"130-133","DOI":"10.1111\/j.1744-1633.2007.00354.x","article-title":"Chronic pancreatitis complicated by pancreaticopericardial fistula.","volume":"11","author":"S Ching","year":"2007","journal-title":"Surgical Practice."},{"key":"ref-9","doi-asserted-by":"publisher","first-page":"160-161","DOI":"10.1097\/MAJ.0b013e3182805779","article-title":"Swinging heart in acute pancreatitis.","volume":"346","author":"S Lamparter","year":"2013","journal-title":"Am J Med Sci."},{"key":"ref-10","doi-asserted-by":"crossref","first-page":"224-7","DOI":"10.1097\/00004836-199610000-00015","article-title":"Recurrent pericardial effusion as a result of chronic pancreatitis. 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clarifications1) Duration of drinking?2) Incidence of fistula formation after blunt trauma abdomen and chronic pancreatitis?","URL":"https:\/\/f1000research.com\/articles\/3-31\/v1#article-response-694","order":2,"name":"article-response-694","label":"Article Comment","group":{"name":"article-comments","label":"Article Comments"}},{"value":"The author(s) declared that no grants were involved in supporting this work","order":3,"name":"grant-information","label":"Grant Information"},{"value":"This is an open access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.Data associated with the article are available under the terms of the Creative Commons Zero \"No rights reserved\" data waiver (CC0 1.0 Public domain dedication).","order":0,"name":"copyright-info","label":"Copyright"}]}}