{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T05:10:03Z","timestamp":1772169003363,"version":"3.50.1"},"update-to":[{"DOI":"10.12688\/f1000research.53365.1","type":"new_version","label":"New version","source":"publisher","updated":{"date-parts":[[2022,1,13]],"date-time":"2022-01-13T00:00:00Z","timestamp":1642032000000}}],"reference-count":32,"publisher":"F1000 Research Ltd","license":[{"start":{"date-parts":[[2022,1,13]],"date-time":"2022-01-13T00:00:00Z","timestamp":1642032000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["f1000research.com"],"crossmark-restriction":false},"short-container-title":["F1000Res"],"abstract":"<ns3:p>Priapism in chronic myeloid leukemia (CML) appears to be an infrequent manifestation as well as a crucial emergency. Here, we report an 18-year-old male presenting with a persistent erection of the penis for 20 days. We evaluated and compared the reported cases within 20 years discussing the management of priapism in CML. Cytoreductive therapy followed by leukapheresis, the administration of tyrosine kinase inhibitor, and intra-cavernosal blood aspiration may resolve the symptoms of priapism. Early intervention for cytoreduction and aspiration are the pivotal keys to successfully impeding the complications.<\/ns3:p>","DOI":"10.12688\/f1000research.53365.2","type":"journal-article","created":{"date-parts":[[2022,1,13]],"date-time":"2022-01-13T06:20:48Z","timestamp":1642054848000},"page":"571","update-policy":"https:\/\/doi.org\/10.12688\/f1000research.crossmark-policy","source":"Crossref","is-referenced-by-count":2,"title":["Case Report: Priapism as The Clinical Presenting Feature of Chronic Myeloid Leukemia: Case Report and 20-Year Literature Review"],"prefix":"10.12688","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1360-5298","authenticated-orcid":false,"given":"Siprianus Ugroseno Yudho","family":"Bintoro","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9306-5425","authenticated-orcid":false,"given":"Pradana Zaky","family":"Romadhon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0522-8659","authenticated-orcid":false,"given":"Satriyo Dwi","family":"Suryantoro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6927-7206","authenticated-orcid":false,"given":"Rusdi Zakki","family":"Aminy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3394-1400","authenticated-orcid":false,"given":"Choirina","family":"Windradi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Krisnina Nurul","family":"Widiyastuti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2560","published-online":{"date-parts":[[2022,1,13]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"155-64","DOI":"10.1111\/j.1365-2141.2012.09151.x","article-title":"How I manage priapism in chronic myeloid leukaemia patients.","volume":"158","author":"R Rodgers","year":"2012","journal-title":"Br J Haematol."},{"key":"ref2","doi-asserted-by":"publisher","first-page":"827-34","DOI":"10.1111\/jsm.12812","article-title":"Priapism as a result of chronic myeloid leukemia: case report, pathology, and review of the literature.","volume":"12","author":"O Shaeer","year":"2015","journal-title":"J Sex Med."},{"key":"ref3","doi-asserted-by":"publisher","first-page":"e104-8","DOI":"10.1590\/S0325-00752011000500016","article-title":"[Priapism in pediatrics: initial presentation of chronic myeloid leukemia].","volume":"109","author":"N 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Assoc."},{"key":"ref14","doi-asserted-by":"publisher","first-page":"373-6","DOI":"10.1016\/j.ajur.2018.12.004","article-title":"Priapism secondary to chronic myeloid leukemia treated by a surgical cavernosa-corpus spongiosum shunt: Case report.","volume":"6","author":"M Qu","year":"2019","journal-title":"Asian J Urol."},{"key":"ref15","doi-asserted-by":"publisher","first-page":"617-9","DOI":"10.1542\/pir.2017-0051","article-title":"Case 3: Priapism in a 13-year-old Boy.","volume":"39","author":"A Clark","year":"2018","journal-title":"Pediatr Rev."},{"key":"ref16","doi-asserted-by":"publisher","first-page":"1442-3","DOI":"10.4103\/0973-1482.199388","article-title":"Priapism as a rare presentation of chronic myeloid leukemia.","volume":"14","author":"P Kumar","year":"2018","journal-title":"J Cancer Res Ther."},{"key":"ref17","first-page":"420-2","article-title":"A rare presentation of chronic myeloid leukaemia with priapism treated with corporoglandular shunting.","volume":"73","author":"T Huei","year":"2018","journal-title":"Med J Malaysia."},{"key":"ref18","doi-asserted-by":"publisher","first-page":"828-30","DOI":"10.4103\/1119-3077.163282","article-title":"Chronic myeloid leukemia presented with priapism: Effective management with prompt leukapheresis.","volume":"18","author":"H Ergenc","year":"2015","journal-title":"Niger J Clin Pract."},{"key":"ref19","first-page":"708-11","article-title":"Ischaemic priapism as a presentation of chronic myeloid leukaemia.","volume":"67","author":"J Villegas Osorio","year":"2014","journal-title":"Arch Esp Urol."},{"key":"ref20","first-page":"39","article-title":"Pediatric priapism: a rare first manifestation of leukemia.","volume":"4","author":"S Hazra","year":"2013","journal-title":"APSP J Case Rep."},{"key":"ref21","doi-asserted-by":"publisher","first-page":"263-7","DOI":"10.1016\/j.transci.2012.03.012","article-title":"Leukapheresis in management hyperleucocytosis induced complications in two 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status","group":{"name":"current-referee-status","label":"Current Referee Status"}},{"value":"10.5256\/f1000research.56738.r89693, Wulyo Rajabto, Division of Hematology-Medical Oncology, Department of Internal Medicine, Dr. Cipto Mangunkusumo General Hospital, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia, 18 Oct 2021, version 1, 1 approved, 1 approved with reservations","URL":"https:\/\/f1000research.com\/articles\/10-571\/v1#referee-response-89693","order":0,"name":"referee-response-89693","label":"Referee Report","group":{"name":"article-reports","label":"Article Reports"}},{"value":"10.5256\/f1000research.80090.r119664, Ritu Gupta, Laboratory Oncology Unit, Dr B.R. Ambedkar IRCH, All India Institute of Medical Sciences (AIIMS), New Delhi, New Delhi, Delhi, India, 14 Jan 2022, version 2, indexed","URL":"https:\/\/f1000research.com\/articles\/10-571\/v2#referee-response-119664","order":1,"name":"referee-response-119664","label":"Referee Report","group":{"name":"article-reports","label":"Article Reports"}},{"value":"The author(s) declared that no grants were involved in supporting this work","order":2,"name":"grant-information","label":"Grant Information"},{"value":"This is an open access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.","order":0,"name":"copyright-info","label":"Copyright"}]}}