{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T05:08:59Z","timestamp":1772168939847,"version":"3.50.1"},"reference-count":11,"publisher":"F1000 Research Ltd","license":[{"start":{"date-parts":[[2022,1,19]],"date-time":"2022-01-19T00:00:00Z","timestamp":1642550400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["f1000research.com"],"crossmark-restriction":false},"short-container-title":["F1000Res"],"abstract":"<ns4:p>\n                    <ns4:bold>Background:<\/ns4:bold>\n                    The molecular distributions of solutes in binary immiscible solvents as used in partition coefficient technique serve as measures of the solute separation, concentration and beneficiation from contaminants.\n                  <\/ns4:p>\n                  <ns4:p>\n                    <ns4:bold>Methods:<\/ns4:bold>\n                    The effects of solute interactions on partition coefficient, k\n                    <ns4:sub>D<\/ns4:sub>\n                    , in selected binary immiscible solvents were investigated at 30\n                    <ns4:sup>0<\/ns4:sup>\n                    C and atmospheric pressure. The activities from the interactions with changes of concentrations within the solvents were analysed. These were done using simple titration method. The solutes were distributed in the binary solvents and the concentrations from the two layers formed were determined by titration method. The interactions of oxalic acid and succinic acid in carbon tetrachloride-water, diethyl ether-water, and n-hexane-water were studied for the partition coefficient values in the respective systems, to determine the nature and degree of the interfering reactions that are affecting the distributions, and to ascertain the best binary solvents from the three systems.\n                  <\/ns4:p>\n                  <ns4:p>\n                    <ns4:bold>Results:<\/ns4:bold>\n                    Oxalic acid has the partition coefficient of 0.0738 in carbon tetrachloride-water with the dimerization constant of -15.7092 and ionization constant of 0.0303. Oxalic acid has the distribution coefficient of 0.0173, dimerization constant of 144.0167 and the ionization constant of 0.0035 in diethyl ether-water. Oxalic acid has the partition coefficient of 0.0279, dimerization constant of 20.2798 and ionization constant of 0.0019 in n-hexane-water. Succinic acid has the partition coefficient of -0.05617, dimerization constant of -18.5655 and ionization constant of 0.0284 in carbon tetrachloride-water. In diethyl ether-water, succinic acid has the partition coefficient of 0.0427, dimerization constant of -18.1611 and ionization constant of 0.0332. In n-hexane-water, succinic acid has the partition coefficient of -0.04274, dimerization constant of 71.9491 and ionization constant of 0.0265.\n                  <\/ns4:p>\n                  <ns4:p>\n                    <ns4:bold>Conclusion:<\/ns4:bold>\n                    From these results, carbon tetrachloride-water is recommended for the purification and extraction of oxalic acid from contaminants. Carbon tetrachloride-water is also the best binary immiscible solvent for succinic acid.\n                  <\/ns4:p>","DOI":"10.12688\/f1000research.55200.1","type":"journal-article","created":{"date-parts":[[2022,1,19]],"date-time":"2022-01-19T10:40:20Z","timestamp":1642588820000},"page":"63","update-policy":"https:\/\/doi.org\/10.12688\/f1000research.crossmark-policy","source":"Crossref","is-referenced-by-count":1,"title":["Comparisons of the effects of solute interactions on partition coefficient, kD, in selected binary immiscible solvents: a case of oxalic acid and succinic acid"],"prefix":"10.12688","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3002-2254","authenticated-orcid":false,"given":"Onyeocha","family":"V. O.","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Onuchukwu","family":"A. I.","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Enemo","family":"R. E.","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2560","published-online":{"date-parts":[[2022,1,19]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"40-52","DOI":"10.18052\/www.scipress.com\/ILCPA.80.40","article-title":"The Dimerization Effects of Some Solutes on the Partition Coefficient (kD) in Binary Immiscible Solvents.","volume":"80","author":"V Onyeocha","year":"2018","journal-title":"Intern. Lett. Chem. Phys. Astrono."},{"key":"ref4","article-title":"Sensitivity Analysis of the Distribution Coefficient, kD, of Nickel with Changing Soil Chemical Properties.","author":"S Staunton","year":"Oct 2004"},{"key":"ref5","first-page":"147","article-title":"Encyclopaedia of Chemical Technology.","volume":"1","author":"K Othmer","year":"1979"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"7385","DOI":"10.1021\/jp4125638","article-title":"Intermolecular Interactions between Molecules in Various Conformational States: The Dimer of Oxalic Acid.","volume":"118","author":"Z Keolopile","year":"2014","journal-title":"J. Phys. Chem. 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Chem."},{"key":"ref25","article-title":"Prediction of effectiveness of solvent using distribution coefficient calculation in solvent extraction with the help of Hansen solubility parameters.","author":"S Kodolikar-Kulkarni","year":"2020"},{"key":"ref26","article-title":"Liquid-liquid extraction of oxalic acid from aqueous solutions with tributyl phosphate and a mixed solvent at 303.15K.","author":"N Barnes","year":"1999"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.5281\/zenodo.5171412","article-title":"Comparisons of the effects of solute interactions on partition coefficient, kD, in selected binary immiscible solvents: a case of oxalic acid and succinic acid.","author":"V Onyeocha","year":"2021"},{"key":"ref29","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-9765113-9-7.50005-5","author":"P Nicholas","year":"2006","journal-title":"Cheremisinoff, Motasem B. Haddadin, Beyond Compliance."}],"container-title":["F1000Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/f1000research.com\/articles\/11-63\/v1\/xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/f1000research.com\/articles\/11-63\/v1\/pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/f1000research.com\/articles\/11-63\/v1\/iparadigms","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,3,22]],"date-time":"2023-03-22T08:50:16Z","timestamp":1679475016000},"score":1,"resource":{"primary":{"URL":"https:\/\/f1000research.com\/articles\/11-63\/v1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,1,19]]},"references-count":11,"URL":"https:\/\/doi.org\/10.12688\/f1000research.55200.1","relation":{"has-review":[{"id-type":"doi","id":"10.5256\/f1000research.58757.r120391","asserted-by":"subject"},{"id-type":"doi","id":"10.5256\/f1000research.58757.r161096","asserted-by":"subject"},{"id-type":"doi","id":"10.5256\/f1000research.58757.r161096","asserted-by":"object"},{"id-type":"doi","id":"10.5256\/f1000research.58757.r120391","asserted-by":"object"}]},"ISSN":["2046-1402"],"issn-type":[{"value":"2046-1402","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,1,19]]},"assertion":[{"value":"Indexed","URL":"https:\/\/f1000research.com\/articles\/11-63\/v1#article-reports","order":0,"name":"referee-status","label":"Referee status","group":{"name":"current-referee-status","label":"Current Referee Status"}},{"value":"10.5256\/f1000research.58757.r120391, Shilpa Prasad Kodolikar, Department of Chemical Engineering, MIT World Peace University, Pune, Maharashtra, 21 Apr 2022, version 1, indexed","URL":"https:\/\/f1000research.com\/articles\/11-63\/v1#referee-response-120391","order":0,"name":"referee-response-120391","label":"Referee Report","group":{"name":"article-reports","label":"Article Reports"}},{"value":"10.5256\/f1000research.58757.r161096, Ana C. Gomez Marigliano, Universidad Nacional de Tucum\u00e1n, Tucum\u00e1n, 22 Mar 2023, version 1, indexed","URL":"https:\/\/f1000research.com\/articles\/11-63\/v1#referee-response-161096","order":1,"name":"referee-response-161096","label":"Referee Report","group":{"name":"article-reports","label":"Article Reports"}},{"value":"The author(s) declared that no grants were involved in supporting this work","order":2,"name":"grant-information","label":"Grant Information"},{"value":"This is an open access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.","order":0,"name":"copyright-info","label":"Copyright"}]}}