{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,11]],"date-time":"2026-07-11T10:05:43Z","timestamp":1783764343191,"version":"3.55.0"},"reference-count":16,"publisher":"F1000 Research Ltd","license":[{"start":{"date-parts":[[2015,12,21]],"date-time":"2015-12-21T00:00:00Z","timestamp":1450656000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["f1000research.com"],"crossmark-restriction":false},"short-container-title":["F1000Res"],"abstract":"<ns4:p>\n                    <ns4:bold>Background:<\/ns4:bold>\n                    Dengue infection during peripartum period, although rare in endemic regions, has challenged clinicians regarding its management, especially if a parturient woman experiences postpartum hemorrhage due to a classical risk factor of maternal bleeding.\n                  <\/ns4:p>\n                  <ns4:p>\n                    <ns4:bold>Case:<\/ns4:bold>\n                    A full-term pregnant Vietnamese woman was diagnosed with polyhydramnios and Dengue with warning signs (DWS). She was administered platelet transfusion prior to delivery and then gave birth to a healthy newborn. After active management of the third stage of labor, the patient suffered a postpartum hemorrhage which was caused by uterine atony and accompanied with thrombocytopenia. Therefore, we decided to administer uterotonic drugs and additionally transfuse platelets.\n                  <\/ns4:p>\n                  <ns4:p>\n                    <ns4:bold>Conclusion:<\/ns4:bold>\n                    We describe a case of postpartum hemorrhage caused by uterine atony and coinciding with Dengue infection during delivery period, which is a rare clinical entity. With timely detection and management, the patient was finally discharged without complications.\n                  <\/ns4:p>","DOI":"10.12688\/f1000research.7589.1","type":"journal-article","created":{"date-parts":[[2015,12,21]],"date-time":"2015-12-21T10:04:31Z","timestamp":1450692271000},"page":"1483","update-policy":"https:\/\/doi.org\/10.12688\/f1000research.crossmark-policy","source":"Crossref","is-referenced-by-count":10,"title":["Case Report: Postpartum hemorrhage associated with Dengue with warning signs in a term pregnancy and delivery"],"prefix":"10.12688","volume":"4","author":[{"given":"Le","family":"Phi Hung","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tran","family":"Diem Nghi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nguyen","family":"Hoang Anh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mai","family":"Van Hieu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nguyen","family":"Thien Luan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nguyen","family":"Phuoc Long","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Than","family":"Trong Thach","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2560","published-online":{"date-parts":[[2015,12,21]]},"reference":[{"key":"ref-1","doi-asserted-by":"publisher","first-page":"1111-7","DOI":"10.1097\/AOG.0b013e31816a49fc","article-title":"Dengue infection in pregnancy: prevalence, vertical transmission, and pregnancy outcome.","volume":"111","author":"P Tan","year":"2008","journal-title":"Obstet Gynecol."},{"key":"ref-2","first-page":"793-6","article-title":"Perinatal dengue infection: a case report and review of literature.","volume":"34","author":"W Janjindamai","year":"2003","journal-title":"Southeast Asian J Trop Med Public Health."},{"key":"ref-3","doi-asserted-by":"publisher","first-page":"248-9","DOI":"10.1093\/clinids\/18.2.248","article-title":"Dengue infection complicated by severe hemorrhage and vertical transmission in a parturient woman.","volume":"18","author":"P Thaithumyanon","year":"1994","journal-title":"Clin Infect Dis."},{"key":"ref-4","first-page":"S628-32","article-title":"Vertical transmission of dengue infection in Thai infants: two case reports.","volume":"86","author":"U Chotigeat","year":"2003","journal-title":"J Med Assoc Thai."},{"key":"ref-5","doi-asserted-by":"publisher","first-page":"1374-7","DOI":"10.1086\/516126","article-title":"Vertical transmission of dengue.","volume":"25","author":"J Chye","year":"1997","journal-title":"Clin Infect Dis."},{"key":"ref-6","first-page":"1039-47","article-title":"ACOG Practice Bulletin: Clinical Management Guidelines for Obstetrician-Gynecologists Number 76, October 2006: postpartum hemorrhage.","volume":"108","year":"2006","journal-title":"Obstet Gynecol."},{"key":"ref-7","first-page":"488-93","article-title":"Perinatal dengue infection.","volume":"32","author":"A Kerdpanich","year":"2001","journal-title":"Southeast Asian J Trop Med Public Health."},{"key":"ref-8","doi-asserted-by":"publisher","first-page":"65","DOI":"10.3389\/fphar.2014.00065","article-title":"Physiologic and pharmacokinetic changes in pregnancy.","volume":"5","author":"M Costantine","year":"2014","journal-title":"Front Pharmacol."},{"key":"ref-9","first-page":"124","article-title":"Handbook for clinical management of dengue","year":"2012"},{"key":"ref-10","doi-asserted-by":"publisher","first-page":"682-4","DOI":"10.1067\/S0022-3476(03)00503-1","article-title":"Preventive transfusion in Dengue shock syndrome-is it necessary?","volume":"143","author":"L Lum","year":"2003","journal-title":"J Pediatr."},{"key":"ref-11","doi-asserted-by":"publisher","first-page":"1262-5","DOI":"10.1086\/597773","article-title":"Lack of efficacy of prophylactic platelet transfusion for severe thrombocytopenia in adults with acute uncomplicated dengue infection.","volume":"48","author":"D Lye","year":"2009","journal-title":"Clin Infect Dis."},{"key":"ref-12","doi-asserted-by":"publisher","DOI":"10.1155\/2015\/313842","article-title":"Thrombocytopenia in Dengue: Interrelationship between Virus and the Imbalance between Coagulation and Fibrinolysis and Inflammatory Mediators.","volume":"2015","author":"E de Azeredo","year":"2015","journal-title":"Mediators Inflamm."},{"key":"ref-13","first-page":"875-82","article-title":"Prevention and management of postpartum hemorrhage.","volume":"75","author":"J Anderson","year":"2007","journal-title":"Am Fam Physician."},{"key":"ref-14","doi-asserted-by":"publisher","first-page":"183-8","DOI":"10.1016\/j.tmaid.2006.11.002","article-title":"Dengue fever and pregnancy - a review and comment.","volume":"5","author":"I Carroll","year":"2007","journal-title":"Travel Med Infect Dis."},{"key":"ref-15","doi-asserted-by":"publisher","first-page":"532-43","DOI":"10.1038\/nri3014","article-title":"Immunity to dengue virus: a tale of original antigenic sin and tropical cytokine storms.","volume":"11","author":"A Rothman","year":"2011","journal-title":"Nat Rev Immunol."},{"key":"ref-16","doi-asserted-by":"publisher","first-page":"1042-7","DOI":"10.1097\/01.inf.0000143644.95692.0e","article-title":"Vertical dengue infection: case reports and review.","volume":"23","author":"S Sirinavin","year":"2004","journal-title":"Pediatr Infect Dis J."}],"container-title":["F1000Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/f1000research.com\/articles\/4-1483\/v1\/xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/f1000research.com\/articles\/4-1483\/v1\/pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/f1000research.com\/articles\/4-1483\/v1\/iparadigms","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,12,5]],"date-time":"2018-12-05T14:11:00Z","timestamp":1544019060000},"score":1,"resource":{"primary":{"URL":"https:\/\/f1000research.com\/articles\/4-1483\/v1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,12,21]]},"references-count":16,"URL":"https:\/\/doi.org\/10.12688\/f1000research.7589.1","relation":{"has-review":[{"id-type":"doi","id":"10.5256\/f1000research.8172.r11676","asserted-by":"subject"},{"id-type":"doi","id":"10.5256\/f1000research.8172.r11878","asserted-by":"subject"},{"id-type":"doi","id":"10.5256\/f1000research.8172.r11675","asserted-by":"subject"},{"id-type":"doi","id":"10.5256\/f1000research.8172.r11878","asserted-by":"object"},{"id-type":"doi","id":"10.5256\/f1000research.8172.r11675","asserted-by":"object"},{"id-type":"doi","id":"10.5256\/f1000research.8172.r11676","asserted-by":"object"}]},"ISSN":["2046-1402"],"issn-type":[{"value":"2046-1402","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,12,21]]},"assertion":[{"value":"Indexed","URL":"https:\/\/f1000research.com\/articles\/4-1483\/v1#article-reports","order":0,"name":"referee-status","label":"Referee status","group":{"name":"current-referee-status","label":"Current Referee Status"}},{"value":"10.5256\/f1000research.8172.r11676, Michael Paech, School of Medicine and Pharmacology, University of Western Australia, Perth, Australia, 04 Jan 2016, version 1, indexed","URL":"https:\/\/f1000research.com\/articles\/4-1483\/v1#referee-response-11676","order":0,"name":"referee-response-11676","label":"Referee Report","group":{"name":"article-reports","label":"Article Reports"}},{"value":"10.5256\/f1000research.8172.r11878, Gamal Serour, Department of Obstetrics and Gynaecology, Al Azhar University, Cairo, Egypt, 11 Jan 2016, version 1, indexed","URL":"https:\/\/f1000research.com\/articles\/4-1483\/v1#referee-response-11878","order":1,"name":"referee-response-11878","label":"Referee Report","group":{"name":"article-reports","label":"Article Reports"}},{"value":"10.5256\/f1000research.8172.r11675, Carolyn Weiniger, Anesthesiology and Critical Care, Hadassah-University Medical Center, Jerusalem, Israel, 14 Jan 2016, version 1, indexed","URL":"https:\/\/f1000research.com\/articles\/4-1483\/v1#referee-response-11675","order":2,"name":"referee-response-11675","label":"Referee Report","group":{"name":"article-reports","label":"Article Reports"}},{"value":"The author(s) declared that no grants were involved in supporting this work","order":3,"name":"grant-information","label":"Grant Information"},{"value":"This is an open access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.","order":0,"name":"copyright-info","label":"Copyright"}]}}