{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T05:11:04Z","timestamp":1772169064335,"version":"3.50.1"},"reference-count":7,"publisher":"F1000 Research Ltd","license":[{"start":{"date-parts":[[2016,6,17]],"date-time":"2016-06-17T00:00:00Z","timestamp":1466121600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["f1000research.com"],"crossmark-restriction":false},"short-container-title":["F1000Res"],"abstract":"<ns4:p>Kikuchi-Fujimoto disease (KFD) is an extremely rare disease with a worldwide distribution and higher prevalence in Asians. It is a benign and self-limiting disorder, characterized by regional cervical lymphadenopathy accompanied with mild fever and night sweats. Lymph node histopathology is diagnostic and treating physicians should be aware of this entity as it may mimic other systemic diseases like systemic lupus erythematosus, tuberculosis, malignant lymphoma, and more rarely adenocarcinoma. Key features on lymph node biopsy are fragmentation, necrosis and karyorrhexis.<\/ns4:p>\n                  <ns4:p>Treatment includes symptomatic care, analgesics-antipyretics, corticosteroids and spontaneous recovery occurs in 1 to 4 months. We report a case of adult polycystic kidney disease (ADPKD) with end stage renal disease and episodes of fever and cervical lymphadenopathy. The infectious screen was negative and on extensive workup, the patient was found to have histiocytic-necrotizing lymphadenitis, which clinched the diagnosis of KFD.<\/ns4:p>","DOI":"10.12688\/f1000research.8992.1","type":"journal-article","created":{"date-parts":[[2016,6,17]],"date-time":"2016-06-17T06:02:52Z","timestamp":1466143372000},"page":"1407","update-policy":"https:\/\/doi.org\/10.12688\/f1000research.crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Case Report: Kikuchi-Fujimoto disease: a diagnostic and therapeutic dilemma following pretransplant nephrectomy for a 2.35 Kg kidney"],"prefix":"10.12688","volume":"5","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2678-0634","authenticated-orcid":false,"given":"Arvind P.","family":"Ganpule","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jaspreet Singh","family":"Chabra","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abhishek G.","family":"Singh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gopal R.","family":"Tak","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shailesh","family":"Soni","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ravindra","family":"Sabnis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mahesh","family":"Desai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2560","published-online":{"date-parts":[[2016,6,17]]},"reference":[{"key":"ref-1","first-page":"222-6","article-title":"Kikuchi-Fujimoto disease: a sheep in wolf's clothing.","volume":"41","author":"A Rammohan","year":"2012","journal-title":"J Otolaryngol Head Neck Surg."},{"key":"ref-3","first-page":"379-80","article-title":"Lymphadenitis showing focal reticulum cells hyperplasia with nuclear debris and phagocytosis: A clinicopathological study.","volume":"35","author":"M Kikuchi","year":"1972","journal-title":"Nippon Ketsueki Gakkai Zasshi."},{"key":"ref-4","doi-asserted-by":"publisher","first-page":"246-53","DOI":"10.1034\/j.1399-0039.1999.540305.x","article-title":"DNA typing of HLA class II genes (HLA-DR, -DQ and -DP) in Japanese patients with histiocytic necrotizing lymphadenitis (Kikuchi's disease).","volume":"54","author":"T Tanaka","year":"1999","journal-title":"Tissue Antigens."},{"key":"ref-5","doi-asserted-by":"publisher","first-page":"328-33","DOI":"10.1097\/00000372-200008000-00006","article-title":"Kikuchi-Fujimoto necrotizing lymphadenitis associated with cutaneous lupus erythematosus: a case report.","volume":"22","author":"C Lopez","year":"2000","journal-title":"Am J Dermatopathol."},{"key":"ref-6","doi-asserted-by":"publisher","first-page":"167-8","DOI":"10.1046\/j.1365-2133.2002.4513_4.x","article-title":"Kikuchi's disease, skin and systemic lupus erythematosus.","volume":"146","author":"S Kaur","year":"2002","journal-title":"Br J Dermatol."},{"key":"ref-7","doi-asserted-by":"publisher","first-page":"401-5","DOI":"10.1016\/S0002-9343(96)00231-8","article-title":"Kikuchi-Fujimoto disease: a benign cause of fever and lymphadenopathy.","volume":"101","author":"A Norris","year":"1996","journal-title":"Am J Med."},{"key":"ref-8","article-title":"Ioachim's lymph node pathology","author":"H Ioachim","year":"2009"}],"container-title":["F1000Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/f1000research.com\/articles\/5-1407\/v1\/xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/f1000research.com\/articles\/5-1407\/v1\/pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/f1000research.com\/articles\/5-1407\/v1\/iparadigms","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,12,5]],"date-time":"2018-12-05T13:00:51Z","timestamp":1544014851000},"score":1,"resource":{"primary":{"URL":"https:\/\/f1000research.com\/articles\/5-1407\/v1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,6,17]]},"references-count":7,"URL":"https:\/\/doi.org\/10.12688\/f1000research.8992.1","relation":{"has-review":[{"id-type":"doi","id":"10.5256\/f1000research.9673.r14541","asserted-by":"subject"},{"id-type":"doi","id":"10.5256\/f1000research.9673.r14562","asserted-by":"subject"},{"id-type":"doi","id":"10.5256\/f1000research.9673.r14541","asserted-by":"object"},{"id-type":"doi","id":"10.5256\/f1000research.9673.r14562","asserted-by":"object"}]},"ISSN":["2046-1402"],"issn-type":[{"value":"2046-1402","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,6,17]]},"assertion":[{"value":"Indexed","URL":"https:\/\/f1000research.com\/articles\/5-1407\/v1#article-reports","order":0,"name":"referee-status","label":"Referee 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Kulkarni, Kulkarni Reconstructive Urology Center, Pune, India, 24 Jun 2016, version 1, indexed","URL":"https:\/\/f1000research.com\/articles\/5-1407\/v1#referee-response-14562","order":1,"name":"referee-response-14562","label":"Referee Report","group":{"name":"article-reports","label":"Article Reports"}},{"value":"The author(s) declared that no grants were involved in supporting this work","order":2,"name":"grant-information","label":"Grant Information"},{"value":"This is an open access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.","order":0,"name":"copyright-info","label":"Copyright"}]}}