{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,3]],"date-time":"2026-08-03T14:25:31Z","timestamp":1785767131287,"version":"3.56.0"},"reference-count":61,"publisher":"F1000 Research Ltd","license":[{"start":{"date-parts":[[2016,9,26]],"date-time":"2016-09-26T00:00:00Z","timestamp":1474848000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["f1000research.com"],"crossmark-restriction":false},"short-container-title":["F1000Res"],"abstract":"<ns4:p>Rhinosinusitis affects a significant portion of the US population, and its management imposes a substantial burden on the healthcare system. The treatment of chronic rhinosinusitis includes initial medical management prior to consideration of surgical intervention. However, if surgery does become necessary, several factors must be considered in order to optimize outcomes. This review evaluates surgical patient selection, perioperative medical management, and the extent of operative intervention, with the goal of improving surgical results, decreasing the need for revision surgery, and enhancing the patient\u2019s quality of life. Specific variations in patient genotypes and phenotypes will be further explored with regard to their implications on surgical outcomes. Additionally, the evidence behind pre- and post-operative antibiotic and steroid use will be evaluated. Finally, we will review evolving surgical tools and techniques that are currently being utilized for the treatment of specific subsets of rhinosinusitis.<\/ns4:p>","DOI":"10.12688\/f1000research.9163.1","type":"journal-article","created":{"date-parts":[[2016,9,26]],"date-time":"2016-09-26T11:06:18Z","timestamp":1474887978000},"page":"2377","update-policy":"https:\/\/doi.org\/10.12688\/f1000research.crossmark-policy","source":"Crossref","is-referenced-by-count":4,"title":["Recent advances in the surgical management of rhinosinusitis"],"prefix":"10.12688","volume":"5","author":[{"given":"Alexandria F.","family":"Jaksha","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erik K.","family":"Weitzel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adrienne M.","family":"Laury","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2560","published-online":{"date-parts":[[2016,9,26]]},"reference":[{"key":"ref-1","doi-asserted-by":"publisher","first-page":"423-7","DOI":"10.1177\/000348941112000701","article-title":"Incremental health care utilization and expenditures for chronic rhinosinusitis in the United States.","volume":"120","author":"N Bhattacharyya","year":"2011","journal-title":"Ann Otol Rhinol Laryngol."},{"key":"ref-2","first-page":"1-207","article-title":"Summary health statistics for U.S. adults: National Health Interview Survey, 2009.","author":"J Pleis","year":"2010","journal-title":"Vital Health Stat 10."},{"key":"ref-3","doi-asserted-by":"publisher","first-page":"598-609","DOI":"10.1177\/0194599815574247","article-title":"Clinical practice guideline (update): Adult Sinusitis Executive Summary.","volume":"152","author":"R Rosenfeld","year":"2015","journal-title":"Otolaryngol Head Neck Surg."},{"key":"ref-4","doi-asserted-by":"publisher","first-page":"4-9","DOI":"10.1002\/alr.21065","article-title":"Medical therapy vs surgery for chronic rhinosinusitis: a prospective, multi-institutional study with 1-year follow-up.","volume":"3","author":"T Smith","year":"2013","journal-title":"Int Forum Allergy Rhinol."},{"key":"ref-5","first-page":"1-298","article-title":"European Position Paper on Rhinosinusitis and Nasal Polyps 2012.","author":"W Fokkens","year":"2012","journal-title":"Rhinol Suppl."},{"key":"ref-6","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1186\/1939-4551-7-25","article-title":"ICON: chronic rhinosinusitis.","volume":"7","author":"C Bachert","year":"2014","journal-title":"World Allergy Organ J."},{"key":"ref-7","doi-asserted-by":"publisher","first-page":"65-76","DOI":"10.1590\/S1806-37132015000100009","article-title":"Chronic rhinosinusitis and nasal polyposis in cystic fibrosis: update on diagnosis and treatment.","volume":"41","author":"S Kang","year":"2015","journal-title":"J Bras Pneumol."},{"key":"ref-8","doi-asserted-by":"publisher","first-page":"S22-209","DOI":"10.1002\/alr.21695","article-title":"International Consensus Statement on Allergy and Rhinology: Rhinosinusitis.","volume":"6","author":"R Orlandi","year":"2016","journal-title":"Int Forum Allergy Rhinol."},{"key":"ref-9","doi-asserted-by":"publisher","first-page":"691-700","DOI":"10.1002\/alr.21541","article-title":"Outcomes of complete vs targeted approaches to endoscopic sinus surgery.","volume":"5","author":"A DeConde","year":"2015","journal-title":"Int Forum Allergy Rhinol."},{"key":"ref-10","doi-asserted-by":"publisher","first-page":"702-15","DOI":"10.1002\/alr.21352","article-title":"Medical management of allergic fungal rhinosinusitis following endoscopic sinus surgery: an evidence-based review and recommendations.","volume":"4","author":"E Gan","year":"2014","journal-title":"Int Forum Allergy Rhinol."},{"key":"ref-11","doi-asserted-by":"publisher","first-page":"1280-9","DOI":"10.1111\/j.1398-9995.2006.01225.x","article-title":"Differentiation of chronic sinus diseases by measurement of inflammatory mediators.","volume":"61","author":"T van Zele","year":"2006","journal-title":"Allergy."},{"key":"ref-12","doi-asserted-by":"publisher","first-page":"390-8","DOI":"10.1111\/j.1749-4486.2006.01275.x","article-title":"The national comparative audit of surgery for nasal polyposis and chronic rhinosinusitis.","volume":"31","author":"C Hopkins","year":"2006","journal-title":"Clin Otolaryngol."},{"key":"ref-13","doi-asserted-by":"publisher","first-page":"1932-5","DOI":"10.1097\/01.mlg.0000147922.12228.1f","article-title":"Significance of nasal polyps in chronic rhinosinusitis: symptoms and surgical outcomes.","volume":"114","author":"R Deal","year":"2004","journal-title":"Laryngoscope."},{"key":"ref-14","doi-asserted-by":"publisher","first-page":"1532-40.e1-2","DOI":"10.1016\/j.jaci.2015.10.012","article-title":"Patient-reported outcome measures for adult chronic rhinosinusitis: A systematic review and quality assessment.","volume":"136","author":"L Rudmik","year":"2015","journal-title":"J Allergy Clin Immunol."},{"key":"ref-15","doi-asserted-by":"publisher","first-page":"1703-6","DOI":"10.1097\/00005537-200310000-00008","article-title":"Outcome analysis of endoscopic sinus surgery in patients with nasal polyps and asthma.","volume":"113","author":"P Batra","year":"2003","journal-title":"Laryngoscope."},{"key":"ref-16","doi-asserted-by":"publisher","first-page":"260-4","DOI":"10.2500\/ajra.2014.28.4024","article-title":"The importance of local eosinophilia in the surgical outcome of chronic rhinosinusitis: a 3-year prospective observational study.","volume":"28","author":"S Vlaminck","year":"2014","journal-title":"Am J Rhinol Allergy."},{"key":"ref-17","doi-asserted-by":"publisher","first-page":"111-7","DOI":"10.1007\/s00011-003-1232-2","article-title":"Chronic rhinosinusitis--need for further classification?","volume":"53","author":"C Rudack","year":"2004","journal-title":"Inflamm Res."},{"key":"ref-18","doi-asserted-by":"publisher","first-page":"463-9","DOI":"10.1002\/alr.21304","article-title":"Histopathological and clinical analysis of chronic rhinosinusitis by subtype.","volume":"4","author":"M Czerny","year":"2014","journal-title":"Int Forum Allergy Rhinol."},{"key":"ref-19","doi-asserted-by":"publisher","first-page":"961-8","DOI":"10.1016\/j.jaci.2008.07.008","article-title":"Different types of T-effector cells orchestrate mucosal inflammation in chronic sinus disease.","volume":"122","author":"N Zhang","year":"2008","journal-title":"J Allergy Clin Immunol."},{"key":"ref-20","doi-asserted-by":"publisher","first-page":"445-50","DOI":"10.2500\/ajr.2006.20.2887","article-title":"Pattern of inflammation and impact of Staphylococcus aureus enterotoxins in nasal polyps from southern China.","volume":"20","author":"N Zhang","year":"2006","journal-title":"Am J Rhinol."},{"key":"ref-21","doi-asserted-by":"publisher","first-page":"478-84","DOI":"10.1016\/j.jaci.2009.05.017","article-title":"Distinct immunopathologic characteristics of various types of chronic rhinosinusitis in adult Chinese.","volume":"124","author":"P Cao","year":"2009","journal-title":"J Allergy Clin Immunol."},{"key":"ref-22","doi-asserted-by":"publisher","first-page":"2341-6","DOI":"10.1002\/lary.24027","article-title":"Patient-centered decision making in the treatment of chronic rhinosinusitis.","volume":"123","author":"Z Soler","year":"2013","journal-title":"Laryngoscope."},{"key":"ref-23","doi-asserted-by":"publisher","first-page":"1054-62","DOI":"10.1016\/j.jaci.2015.11.019","article-title":"Cluster analysis and prediction of treatment outcomes for chronic rhinosinusitis.","volume":"137","author":"Z Soler","year":"2016","journal-title":"J Allergy Clin Immunol."},{"key":"ref-24","doi-asserted-by":"publisher","first-page":"988-92","DOI":"10.1001\/archoto.2010.162","article-title":"Cystic fibrosis and endoscopic sinus surgery: Relationship between nasal polyposis and likelihood of revision endoscopic sinus surgery in patients with cystic fibrosis.","volume":"136","author":"S Rickert","year":"2010","journal-title":"Arch Otolaryngol Head Neck Surg."},{"key":"ref-25","doi-asserted-by":"publisher","first-page":"358-63","DOI":"10.1016\/j.otohns.2009.05.034","article-title":"Outcomes of sinus surgery in adults with cystic fibrosis.","volume":"141","author":"A Khalid","year":"2009","journal-title":"Otolaryngol Head Neck Surg."},{"key":"ref-26","doi-asserted-by":"publisher","first-page":"623-31","DOI":"10.1097\/MCP.0000000000000107","article-title":"Management of the upper airway in cystic fibrosis.","volume":"20","author":"E Illing","year":"2014","journal-title":"Curr Opin Pulm Med."},{"key":"ref-27","first-page":"99-104","article-title":"[Endoscopic endonasal ethmoidectomy in severe sinusitis of cystic fibrosis. Mid-term results in 12 patients].","volume":"114","author":"A Coste","year":"1997","journal-title":"Ann Otolaryngol Chir Cervicofac."},{"key":"ref-28","doi-asserted-by":"publisher","first-page":"CD006991","DOI":"10.1002\/14651858.CD006991.pub2","article-title":"Surgical versus medical interventions for chronic rhinosinusitis with nasal polyps.","author":"J Rimmer","year":"2014","journal-title":"Cochrane Database Syst Rev."},{"key":"ref-29","first-page":"97-8","article-title":"Phenotyping, endotyping and clinical decision-making.","volume":"54","author":"W Fokkens","year":"2016","journal-title":"Rhinology."},{"key":"ref-30","doi-asserted-by":"publisher","first-page":"911-9","DOI":"10.1007\/s00405-015-3667-9","article-title":"Efficacy of ESS in chronic rhinosinusitis with and without nasal polyposis: a Danish cohort study.","volume":"273","author":"H Lind","year":"2016","journal-title":"Eur Arch Otorhinolaryngol."},{"key":"ref-31","doi-asserted-by":"publisher","first-page":"633-9","DOI":"10.1016\/j.otohns.2008.12.048","article-title":"Symptom-specific outcomes of endoscopic sinus surgery: a systematic review.","volume":"140","author":"A Chester","year":"2009","journal-title":"Otolaryngol Head Neck Surg."},{"key":"ref-32","doi-asserted-by":"crossref","first-page":"537-43","DOI":"10.1177\/194589240501900601","article-title":"Evidence supporting endoscopic sinus surgery in the management of adult chronic rhinosinusitis: a systematic review.","volume":"19","author":"T Smith","year":"2005","journal-title":"Am J Rhinol."},{"key":"ref-33","doi-asserted-by":"publisher","first-page":"649-63","DOI":"10.2217\/cpr.14.71","article-title":"Updates in the management of chronic rhinosinusitis.","volume":"11","author":"A Slovick","year":"2014","journal-title":"Clin Pract."},{"key":"ref-34","doi-asserted-by":"publisher","first-page":"734-40","DOI":"10.3760\/cma.j.issn.1673-0860.2013.09.008","article-title":"[A prospective multicenter clinical trial of medical and surgical treatment for chronic rhinosinusitis].","volume":"48","author":"D Dilidaer","year":"2013","journal-title":"Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi."},{"key":"ref-35","doi-asserted-by":"publisher","first-page":"25-33","DOI":"10.1002\/alr.21666","article-title":"TAS2R38 genotype predicts surgical outcome in nonpolypoid chronic rhinosinusitis.","volume":"6","author":"N Adappa","year":"2016","journal-title":"Int Forum Allergy Rhinol."},{"key":"ref-36","doi-asserted-by":"publisher","first-page":"1449-1456.e4","DOI":"10.1016\/j.jaci.2015.12.1324","article-title":"Inflammatory endotypes of chronic rhinosinusitis based on cluster analysis of biomarkers.","volume":"137","author":"P Tomassen","year":"2016","journal-title":"J Allergy Clin Immunol."},{"key":"ref-37","doi-asserted-by":"publisher","first-page":"192-8","DOI":"10.2500\/ajra.2014.28.4033","article-title":"Differences in initial immunoprofiles between recurrent and nonrecurrent chronic rhinosinusitis with nasal polyps.","volume":"28","author":"T van Zele","year":"2014","journal-title":"Am J Rhinol Allergy."},{"key":"ref-38","doi-asserted-by":"publisher","first-page":"1683-90","DOI":"10.3349\/ymj.2014.55.6.1683","article-title":"Availability of preoperative systemic steroids on endoscopic sinus surgery for chronic rhinosinusitis with nasal polyposis.","volume":"55","author":"S Hong","year":"2014","journal-title":"Yonsei Med J."},{"key":"ref-39","doi-asserted-by":"publisher","first-page":"497-503","DOI":"10.1002\/alr.21122","article-title":"National survey on the use of preoperative systemic steroids in endoscopic sinus surgery.","volume":"3","author":"J Gonz\u00e1lez-Castro","year":"2013","journal-title":"Int Forum Allergy Rhinol."},{"key":"ref-40","doi-asserted-by":"publisher","first-page":"470-5","DOI":"10.1016\/j.bjorl.2014.08.011","article-title":"Effectiveness of balloon sinuplasty in patients with chronic rhinosinusitis without polyposis.","volume":"80","author":"C Abreu","year":"2014","journal-title":"Braz J Otorhinolaryngol."},{"key":"ref-41","first-page":"3-19","article-title":"Role of corticosteroids in Functional Endoscopic Sinus Surgery--a systematic review and meta-analysis.","volume":"54","author":"V Pundir","year":"2016","journal-title":"Rhinology."},{"key":"ref-42","doi-asserted-by":"publisher","first-page":"236-43","DOI":"10.1007\/s11882-012-0329-5","article-title":"Oral steroid therapy in chronic rhinosinusitis with and without nasal polyposis.","volume":"13","author":"B Howard","year":"2013","journal-title":"Curr Allergy Asthma Rep."},{"key":"ref-43","first-page":"2-10","article-title":"Functional endoscopic sinus surgery: 5 year follow up and results of a prospective, randomised, stratified, double-blind, placebo controlled study of postoperative fluticasone propionate aqueous nasal spray.","volume":"43","author":"J Rowe-Jones","year":"2005","journal-title":"Rhinology."},{"key":"ref-44","first-page":"280-6","article-title":"Effect of corticosteroids on wound healing after endoscopic sinus surgery.","volume":"47","author":"M Jorissen","year":"2009","journal-title":"Rhinology."},{"key":"ref-45","doi-asserted-by":"publisher","first-page":"296-302","DOI":"10.1001\/archoto.2009.2","article-title":"Use of mometasone furoate to prevent polyp relapse after endoscopic sinus surgery.","volume":"135","author":"P Stj\u00e4rn","year":"2009","journal-title":"Arch Otolaryngol Head Neck Surg."},{"key":"ref-46","doi-asserted-by":"publisher","first-page":"1019-32","DOI":"10.1016\/j.otc.2012.06.006","article-title":"Evidence-based practice: postoperative care in endoscopic sinus surgery.","volume":"45","author":"L Rudmik","year":"2012","journal-title":"Otolaryngol Clin North Am."},{"key":"ref-47","doi-asserted-by":"publisher","first-page":"1-28","DOI":"10.1097\/MLG.0b013e31814842f8","article-title":"Impact of perioperative systemic steroids on surgical outcomes in patients with chronic rhinosinusitis with polyposis: evaluation with the novel Perioperative Sinus Endoscopy (POSE) scoring system.","volume":"117","author":"E Wright","year":"2007","journal-title":"Laryngoscope."},{"key":"ref-48","doi-asserted-by":"publisher","first-page":"557-67","DOI":"10.1002\/alr.21769","article-title":"Defining appropriateness criteria for endoscopic sinus surgery during management of uncomplicated adult chronic rhinosinusitis: a RAND\/UCLA appropriateness study.","volume":"6","author":"L Rudmik","year":"2016","journal-title":"Int Forum Allergy Rhinol."},{"key":"ref-49","doi-asserted-by":"publisher","first-page":"e146-57","DOI":"10.2500\/ajra.2013.27.3950","article-title":"The use of postoperative topical corticosteroids in chronic rhinosinusitis with nasal polyps: a systematic review and meta-analysis.","volume":"27","author":"M Fandi\u00f1o","year":"2013","journal-title":"Am J Rhinol Allergy."},{"key":"ref-50","doi-asserted-by":"publisher","first-page":"708-11","DOI":"10.1002\/alr.21189","article-title":"Budesonide nasal irrigations in the postoperative management of chronic rhinosinusitis.","volume":"3","author":"D Jang","year":"2013","journal-title":"Int Forum Allergy Rhinol."},{"key":"ref-51","doi-asserted-by":"publisher","first-page":"1069-1076.e4","DOI":"10.1016\/j.jaci.2010.02.020","article-title":"Oral steroids and doxycycline: two different approaches to treat nasal polyps.","volume":"125","author":"T van Zele","year":"2010","journal-title":"J Allergy Clin Immunol."},{"key":"ref-52","doi-asserted-by":"publisher","first-page":"1048-55","DOI":"10.1002\/lary.25052","article-title":"Controlled trial for long-term low-dose erythromycin after sinus surgery for chronic rhinosinusitis.","volume":"125","author":"B Haxel","year":"2015","journal-title":"Laryngoscope."},{"key":"ref-53","doi-asserted-by":"publisher","first-page":"306-9","DOI":"10.2500\/ajra.2010.24.3475","article-title":"Prophylactic antibiotics in endoscopic sinus surgery: a short follow-up study.","volume":"24","author":"S Albu","year":"2010","journal-title":"Am J Rhinol Allergy."},{"key":"ref-54","doi-asserted-by":"publisher","first-page":"455-60","DOI":"10.1016\/j.jcf.2014.02.006","article-title":"Efficacy and tolerability of a new nasal spray formulation containing hyaluronate and tobramycin in cystic fibrosis patients with bacterial rhinosinusitis.","volume":"13","author":"M Di Cicco","year":"2014","journal-title":"J Cyst Fibros."},{"key":"ref-55","doi-asserted-by":"publisher","first-page":"493-6","DOI":"10.1002\/alr.21131","article-title":"Comparison of anatomical abnormalities in patients with limited and diffuse chronic rhinosinusitis.","volume":"3","author":"R Jain","year":"2013","journal-title":"Int Forum Allergy Rhinol."},{"key":"ref-56","first-page":"219-26","article-title":"Anatomical variations and sinusitis.","volume":"51","author":"M Jorissen","year":"1997","journal-title":"Acta Otorhinolaryngol Belg."},{"key":"ref-57","doi-asserted-by":"publisher","first-page":"347-64","DOI":"10.1016\/S0030-6665(03)00171-3","article-title":"Maxillary sinus disease of odontogenic origin.","volume":"37","author":"P Mehra","year":"2004","journal-title":"Otolaryngol Clin North Am."},{"key":"ref-58","doi-asserted-by":"publisher","first-page":"667-73","DOI":"10.1002\/alr.21533","article-title":"Medical therapy vs surgery for recurrent acute rhinosinusitis.","volume":"5","author":"M Costa","year":"2015","journal-title":"Int Forum Allergy Rhinol."},{"key":"ref-59","doi-asserted-by":"publisher","first-page":"323-9","DOI":"10.2500\/ajra.2014.28.4064","article-title":"Standalone balloon dilation versus sinus surgery for chronic rhinosinusitis: a prospective, multicenter, randomized, controlled trial with 1-year follow-up.","volume":"28","author":"N Bikhazi","year":"2014","journal-title":"Am J Rhinol Allergy."},{"key":"ref-60","doi-asserted-by":"publisher","first-page":"511-8","DOI":"10.1177\/000348941112000804","article-title":"Balloon dilation of the frontal recess: a randomized clinical trial.","volume":"120","author":"G Plaza","year":"2011","journal-title":"Ann Otol Rhinol Laryngol."},{"key":"ref-61","doi-asserted-by":"publisher","first-page":"167-73","DOI":"10.1002\/alr.21432","article-title":"Randomized controlled trial: hybrid technique using balloon dilation of the frontal sinus drainage pathway.","volume":"5","author":"I Hathorn","year":"2015","journal-title":"Int Forum Allergy Rhinol."}],"container-title":["F1000Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/f1000research.com\/articles\/5-2377\/v1\/xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/f1000research.com\/articles\/5-2377\/v1\/pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/f1000research.com\/articles\/5-2377\/v1\/iparadigms","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,3,22]],"date-time":"2019-03-22T11:31:57Z","timestamp":1553254317000},"score":1,"resource":{"primary":{"URL":"https:\/\/f1000research.com\/articles\/5-2377\/v1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,9,26]]},"references-count":61,"URL":"https:\/\/doi.org\/10.12688\/f1000research.9163.1","relation":{"has-review":[{"id-type":"doi","id":"10.5256\/f1000research.9860.r16608","asserted-by":"subject"},{"id-type":"doi","id":"10.5256\/f1000research.9860.r16615","asserted-by":"subject"},{"id-type":"doi","id":"10.5256\/f1000research.9860.r16617","asserted-by":"subject"},{"id-type":"doi","id":"10.5256\/f1000research.9860.r16618","asserted-by":"subject"}]},"ISSN":["2046-1402"],"issn-type":[{"value":"2046-1402","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,9,26]]},"assertion":[{"value":"Indexed","URL":"https:\/\/f1000research.com\/articles\/5-2377\/v1#article-reports","order":0,"name":"referee-status","label":"Referee status","group":{"name":"current-referee-status","label":"Current Referee Status"}},{"value":"10.5256\/f1000research.9860.r16608, Marc Tewfik, Department of Otolaryngology, Head and Neck Surgery, McGill University, Montreal, Canada, 26 Sep 2016, version 1, indexed","URL":"https:\/\/f1000research.com\/articles\/5-2377\/v1#referee-response-16608","order":0,"name":"referee-response-16608","label":"Referee Report","group":{"name":"article-reports","label":"Article Reports"}},{"value":"10.5256\/f1000research.9860.r16615, Peter-John Wormald, Department of Surgery, Otorhinolaryngology, Head and Neck Surgery, The Queen Elizabeth Hospital, University of Adelaide, Adelaide, Australia, 26 Sep 2016, version 1, indexed","URL":"https:\/\/f1000research.com\/articles\/5-2377\/v1#referee-response-16615","order":1,"name":"referee-response-16615","label":"Referee Report","group":{"name":"article-reports","label":"Article Reports"}},{"value":"10.5256\/f1000research.9860.r16617, Simon Robinson, Endoscopic Sinus and Skull Base Surgery, Wakefield Hospital, Wellington, New Zealand, 26 Sep 2016, version 1, indexed","URL":"https:\/\/f1000research.com\/articles\/5-2377\/v1#referee-response-16617","order":2,"name":"referee-response-16617","label":"Referee Report","group":{"name":"article-reports","label":"Article Reports"}},{"value":"10.5256\/f1000research.9860.r16618, Richard Douglas, Department of Surgery, University of Auckland, Auckland, New Zealand, 26 Sep 2016, version 1, indexed","URL":"https:\/\/f1000research.com\/articles\/5-2377\/v1#referee-response-16618","order":3,"name":"referee-response-16618","label":"Referee Report","group":{"name":"article-reports","label":"Article Reports"}},{"value":"The author(s) declared that no grants were involved in supporting this work","order":4,"name":"grant-information","label":"Grant Information"},{"value":"This is an open access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.","order":0,"name":"copyright-info","label":"Copyright"}]}}