{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T05:10:36Z","timestamp":1772169036828,"version":"3.50.1"},"reference-count":8,"publisher":"F1000 Research Ltd","license":[{"start":{"date-parts":[[2019,9,20]],"date-time":"2019-09-20T00:00:00Z","timestamp":1568937600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000865","name":"Bill and Melinda Gates Foundation","doi-asserted-by":"publisher","award":["OPP1184344"],"award-info":[{"award-number":["OPP1184344"]}],"id":[{"id":"10.13039\/100000865","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["gatesopenresearch.org"],"crossmark-restriction":false},"short-container-title":["Gates Open Res"],"abstract":"<ns4:p>Scabies was adopted by the World Health Organization (WHO) as a Neglected Tropical Disease in 2017. There is currently no formal global scabies control programmes or existing WHO guidelines on scabies control although at least two countries, Fiji and Ethiopia, have adopted national approaches to scabies control. In February 2019 WHO held a first Informal Consultation on a Framework for Scabies Control, in part as a response to multiple national requests for guidance on public health management in high disease burden areas. Below we outline control strategies proposed at this meeting and summarise the role that modelling can play in supporting the development of evidence to translate these proposals into formal WHO recommendations and national and global control programmes. Provisional proposals discussed at the WHO Informal Consultation for a scabies control programme include the use of mass drug administration when the community prevalence of scabies is \u2265 10% (generally considered to reflect a childhood prevalence of at least 20%) and the use of intensified case management when the prevalence is below 10%.<\/ns4:p>","DOI":"10.12688\/gatesopenres.13064.1","type":"journal-article","created":{"date-parts":[[2019,9,20]],"date-time":"2019-09-20T05:40:05Z","timestamp":1568958005000},"page":"1542","update-policy":"https:\/\/doi.org\/10.12688\/gatesopenres.crossmark-policy","source":"Crossref","is-referenced-by-count":14,"title":["Insights from mathematical modelling on the proposed WHO 2030 goals for scabies"],"prefix":"10.12688","volume":"3","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7585-4743","authenticated-orcid":false,"given":"Michael","family":"Marks","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jodie","family":"McVernon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel","family":"Engelman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John","family":"Kaldor","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrew","family":"Steer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2560","published-online":{"date-parts":[[2019,9,20]]},"reference":[{"key":"ref-1","doi-asserted-by":"publisher","first-page":"1718-1727","DOI":"10.1056\/NEJMcp052784","article-title":"Clinical practices. Scabies.","volume":"354","author":"O Chosidow","year":"2006","journal-title":"N Engl J Med."},{"key":"ref-2","doi-asserted-by":"publisher","first-page":"56-66","DOI":"10.1016\/j.epidem.2017.02.002","article-title":"Measuring and modelling the effects of systematic non-adherence to mass drug administration.","volume":"18","author":"L Dyson","year":"2017","journal-title":"Epidemics."},{"key":"ref-3","doi-asserted-by":"publisher","DOI":"10.3390\/tropicalmed3030098","article-title":"Control Strategies for Scabies.","volume":"3","author":"D Engelman","year":"2018","journal-title":"Trop Med Infect Dis."},{"key":"ref-4","doi-asserted-by":"publisher","first-page":"163-73","DOI":"10.1016\/j.mbs.2018.08.007","article-title":"A biological model of scabies infection dynamics and treatment informs mass drug administration strategies to increase the likelihood of elimination.","volume":"309","author":"M Lydeamore","year":"2019","journal-title":"Math Biosci."},{"key":"ref-5","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciz444","article-title":"Prevalence of scabies and impetigo three years after mass drug administration with ivermectin and azithromycin.","author":"M Marks","year":"2019","journal-title":"Clin Infect Dis."},{"key":"ref-6","doi-asserted-by":"publisher","first-page":"510-518","DOI":"10.1016\/S1473-3099(18)30790-4","article-title":"Efficacy of mass drug administration with ivermectin for control of scabies and impetigo, with coadministration of azithromycin: a single-arm community intervention trial.","volume":"19","author":"L Romani","year":"2019a","journal-title":"Lancet Infect Dis."},{"key":"ref-7","doi-asserted-by":"publisher","first-page":"186-187","DOI":"10.1056\/NEJMc1808439","article-title":"Mass Drug Administration for Scabies - 2 Years of Follow-up.","volume":"381","author":"L Romani","year":"2019b","journal-title":"N Engl J Med."},{"key":"ref-8","doi-asserted-by":"publisher","first-page":"2305-13","DOI":"10.1056\/NEJMoa1500987","article-title":"Mass Drug Administration for Scabies Control in a Population with Endemic Disease.","volume":"373","author":"L Romani","year":"2015","journal-title":"N Engl J Med."}],"container-title":["Gates Open Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/gatesopenresearch.org\/articles\/3-1542\/v1\/xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/gatesopenresearch.org\/articles\/3-1542\/v1\/pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/gatesopenresearch.org\/articles\/3-1542\/v1\/iparadigms","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,10,14]],"date-time":"2019-10-14T09:20:10Z","timestamp":1571044810000},"score":1,"resource":{"primary":{"URL":"https:\/\/gatesopenresearch.org\/articles\/3-1542\/v1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,9,20]]},"references-count":8,"URL":"https:\/\/doi.org\/10.12688\/gatesopenres.13064.1","relation":{"has-review":[{"id-type":"doi","id":"10.21956\/gatesopenres.14195.r27913","asserted-by":"subject"},{"id-type":"doi","id":"10.21956\/gatesopenres.14195.r27912","asserted-by":"subject"},{"id-type":"doi","id":"10.21956\/gatesopenres.14195.r27914","asserted-by":"object"},{"id-type":"doi","id":"10.21956\/gatesopenres.14195.r27913","asserted-by":"object"},{"id-type":"doi","id":"10.21956\/gatesopenres.14195.r27912","asserted-by":"object"}]},"ISSN":["2572-4754"],"issn-type":[{"value":"2572-4754","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,9,20]]},"assertion":[{"value":"Indexed","URL":"https:\/\/gatesopenresearch.org\/articles\/3-1542\/v1#article-reports","order":0,"name":"referee-status","label":"Referee status","group":{"name":"current-referee-status","label":"Current Referee Status"}},{"value":"10.21956\/gatesopenres.14195.r27913, Jorg Heukelbach, Department of Community Health, School of Medicine, Federal University of Cear\u00e1, Fortaleza, Brazil, 26 Sep 2019, version 1, indexed","URL":"https:\/\/gatesopenresearch.org\/articles\/3-1542\/v1#referee-response-27913","order":0,"name":"referee-response-27913","label":"Referee Report","group":{"name":"article-reports","label":"Article Reports"}},{"value":"10.21956\/gatesopenres.14195.r27912, Ymkje Stienstra, University Medical Center Groningen, Department of Internal Medicine\u2014Infectious Diseases, University of Groningen, Groningen, The Netherlands, 14 Oct 2019, version 1, indexed","URL":"https:\/\/gatesopenresearch.org\/articles\/3-1542\/v1#referee-response-27912","order":1,"name":"referee-response-27912","label":"Referee Report","group":{"name":"article-reports","label":"Article Reports"}},{"value":"This work was supported by the Bill and Melinda Gates Foundation [OPP1184344]. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.","order":2,"name":"grant-information","label":"Grant Information"},{"value":"This is an open access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.","order":0,"name":"copyright-info","label":"Copyright"}]}}