{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T16:20:18Z","timestamp":1790698818461,"version":"4.1.0"},"reference-count":45,"publisher":"F1000 Research Ltd","license":[{"start":{"date-parts":[[2019,9,13]],"date-time":"2019-09-13T00:00:00Z","timestamp":1568332800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Gates Foundation","award":["OPP1186851"],"award-info":[{"award-number":["OPP1186851"]}]},{"name":"Gates Foundation","award":["OPP1156227"],"award-info":[{"award-number":["OPP1156227"]}]},{"name":"Gates Foundation","award":["OPP1184344"],"award-info":[{"award-number":["OPP1184344"]}]}],"content-domain":{"domain":["gatesopenresearch.org"],"crossmark-restriction":false},"short-container-title":["Gates Open Res"],"abstract":"<ns4:p>The Global Programme to Eliminate Lymphatic Filariasis was launched in 2000 to eliminate lymphatic filariasis (LF) as a public health problem by 1) interrupting transmission through mass drug administration (MDA) and 2) offering basic care to those suffering from lymphoedema or hydrocele due to the infection. Although impressive progress has been made, the initial target year of 2020 will not be met everywhere. The World Health Organization recently proposed 2030 as the new target year for elimination of lymphatic filariasis (LF) as a public health problem. In this letter, LF modelers of the Neglected Tropical Diseases (NTDs) Modelling Consortium reflect on the proposed targets for 2030 from a quantitative perspective. While elimination as a public health problem seems technically and operationally feasible, it is uncertain whether this will eventually also lead to complete elimination of transmission. The risk of resurgence needs to be mitigated by strong surveillance after stopping interventions and sometimes perhaps additional interventions.<\/ns4:p>","DOI":"10.12688\/gatesopenres.13065.1","type":"journal-article","created":{"date-parts":[[2019,9,13]],"date-time":"2019-09-13T12:15:08Z","timestamp":1568376908000},"page":"1538","update-policy":"https:\/\/doi.org\/10.12688\/gatesopenres.crossmark-policy","source":"Crossref","is-referenced-by-count":44,"title":["The roadmap towards elimination of lymphatic filariasis by 2030: insights from quantitative and mathematical modelling"],"prefix":"10.12688","volume":"3","author":[{"name":"NTD Modelling Consortium Lymphatic Filariasis Group","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2560","published-online":{"date-parts":[[2019,9,13]]},"reference":[{"key":"ref-1","article-title":"Elimination of lymphatic filariasis as a public health problem.","year":"1997"},{"key":"ref-2","first-page":"589-602","article-title":"Global Programme to Eliminate Lymphatic Filariasis: Progress report, 2017.","volume":"93","year":"2018","journal-title":"Wkly Epidemiol Rec."},{"key":"ref-3","article-title":"London Declaration on Neglected Tropical Diseases","year":"2012"},{"key":"ref-4","article-title":"General Assembly Resolution A\/Res\/70\/1: Transforming our world: the 2030 agenda for sustainable development (21 October 2015).","year":"2015"},{"key":"ref-5","article-title":"WHO launches global consultations for a new Roadmap on neglected tropical diseases","year":"2019"},{"key":"ref-6","article-title":"NTD Roadmap 2021-2030.","year":"2019"},{"key":"ref-7","doi-asserted-by":"publisher","first-page":"630","DOI":"10.1186\/s13071-015-1235-1","article-title":"Quantitative analyses and modelling to support achievement of the 2020 goals for nine neglected tropical diseases.","volume":"8","author":"T Hollingsworth","year":"2015","journal-title":"Parasit Vectors."},{"key":"ref-8","doi-asserted-by":"publisher","first-page":"S237-S44","DOI":"10.1093\/cid\/ciy284","article-title":"Counting Down the 2020 Goals for 9 Neglected Tropical Diseases: What Have We Learned From Quantitative Analysis and Transmission Modeling?","volume":"66","author":"T Hollingsworth","year":"2018","journal-title":"Clin Infect Dis."},{"key":"ref-9","doi-asserted-by":"publisher","first-page":"S260-S6","DOI":"10.1093\/cid\/ciy003","article-title":"Are Alternative Strategies Required to Accelerate the Global Elimination of Lymphatic Filariasis? 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Graves, College of Public Health, Medical and Veterinary Sciences, James Cook University, Cairns, Queensland, Australia, 02 Oct 2019, version 1, indexed","URL":"https:\/\/gatesopenresearch.org\/articles\/3-1538\/v1#referee-response-27852","order":0,"name":"referee-response-27852","label":"Referee Report","group":{"name":"article-reports","label":"Article Reports"}},{"value":"10.21956\/gatesopenres.14196.r27999, Ryan E. Wiegand, Division of Parasitic Diseases and Malaria, Center for Global Health, Centers for Disease Control and Prevention, Atlanta, GA, USA, 05 Nov 2019, version 1, indexed","URL":"https:\/\/gatesopenresearch.org\/articles\/3-1538\/v1#referee-response-27999","order":1,"name":"referee-response-27999","label":"Referee Report","group":{"name":"article-reports","label":"Article Reports"}},{"value":"This work was supported by the Bill and Melinda Gates Foundation through a grant [OPP1184344] for the NTD Modelling Consortium (to ELD, CF, TDH, EM, JMP, MES, WAS, PT, SJdV) and grants [OPP1156227, OPP1186851] for making geospatial projections for Africa (to ELD, CF, TDH, PK, EM, JMP, MES, WAS, PT, SJdV). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.","order":2,"name":"grant-information","label":"Grant Information"},{"value":"This is an open access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.","order":0,"name":"copyright-info","label":"Copyright"}]}}