{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T05:27:41Z","timestamp":1777613261057,"version":"3.51.4"},"update-to":[{"DOI":"10.12688\/gatesopenres.13105.1","type":"new_version","label":"New version","source":"publisher","updated":{"date-parts":[[2021,3,10]],"date-time":"2021-03-10T00:00:00Z","timestamp":1615334400000}}],"reference-count":25,"publisher":"F1000 Research Ltd","license":[{"start":{"date-parts":[[2021,3,10]],"date-time":"2021-03-10T00:00:00Z","timestamp":1615334400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Gates Foundation","award":["OPP1190786"],"award-info":[{"award-number":["OPP1190786"]}]}],"content-domain":{"domain":["gatesopenresearch.org"],"crossmark-restriction":false},"short-container-title":["Gates Open Res"],"abstract":"<ns3:p>\n                    <ns3:bold>Background:<\/ns3:bold>\n                    Vaccination is the best way to protect newborns and mothers against tetanus. The number of doses of Td vaccine recommended by the Expanded Program of Immunization is based on documented protective immune response. During this decade, the Foumban Health District (FHD) was the seat of an epidemic despite the satisfactory administrative immunization coverage. This study was conducted in 2019 in the FHD to assess tetanus vaccine coverage among mothers for their last pregnancy and the cumulative number of vaccine doses administered to the mothers.\n                  <\/ns3:p>\n                  <ns3:p>\n                    <ns3:bold>Method:<\/ns3:bold>\n                    This was a descriptive cross-sectional study conducted in the FHD in 2019. Mothers living in the district with at least one child younger than five years were included and were selected by random stratified cluster sampling. Trained surveyors used a face-to-face questionnaire, data extraction grid and data-tracking grid to review and collect data from antenatal care booklets, vaccination cards and the women\u2019s own reports of immunization. The immunization coverage per vaccine dose and vaccination completeness rate were estimated.\n                  <\/ns3:p>\n                  <ns3:p>\n                    <ns3:bold>Results:<\/ns3:bold>\n                    From 621 women visited, 602 (96.9%) responded. A total of 176\/511 women (34.4%) had evidence of vaccination. For the last pregnancy, the two-dose immunization proportion was 21.7% (111\/511) for documented coverage and 47.6% (243\/511) for undocumented coverage. 306\/570 women (53.7%) had received more than the recommended five doses necessary for lifetime protection. The recruitment, two and five doses completeness rates were 99.9% (569\/570), 95.8% (546\/570) and 65.3% (372\/570), respectively.\n                  <\/ns3:p>\n                  <ns3:p>\n                    <ns3:bold>Conclusion:<\/ns3:bold>\n                    More than half of mothers received more doses of tetanus toxoid vaccine than necessary in FHD. This increased the resources needed and the cost of vaccination. Health personnel should be trained and supervised to assess pregnant women\u2019s vaccination status before planning the number of vaccine doses to be administered during pregnancy.\n                  <\/ns3:p>","DOI":"10.12688\/gatesopenres.13105.2","type":"journal-article","created":{"date-parts":[[2021,3,10]],"date-time":"2021-03-10T11:50:07Z","timestamp":1615377007000},"page":"46","update-policy":"https:\/\/doi.org\/10.12688\/gatesopenres.crossmark-policy","source":"Crossref","is-referenced-by-count":2,"title":["Tetanus vaccine coverage in recommended and more than recommended doses among mothers in a West Cameroon health district: a cross sectional study"],"prefix":"10.12688","volume":"4","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3780-7954","authenticated-orcid":false,"given":"Igor","family":"Nguemouo Nguegang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin","family":"Nguetsop","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Linda Evans","family":"Eba Ze","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Trevor","family":"Anyambod Mboh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2250-5590","authenticated-orcid":false,"given":"Dominique Majoric","family":"Omokolo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ruth","family":"Noutakdie Fossi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Etienne","family":"Guenou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jerome","family":"Ateudjieu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2560","published-online":{"date-parts":[[2021,3,10]]},"reference":[{"key":"ref-1","doi-asserted-by":"publisher","first-page":"362-370","DOI":"10.1016\/S0140-6736(14)60236-1","article-title":"Maternal and neonatal tetanus.","volume":"385","author":"C Thwaites","year":"2015","journal-title":"Lancet."},{"key":"ref-2","doi-asserted-by":"publisher","first-page":"1947-1959","DOI":"10.1016\/S0140-6736(07)61261-6","article-title":"Maternal and neonatal tetanus.","volume":"370","author":"M Roper","year":"2007","journal-title":"Lancet."},{"key":"ref-3","article-title":"Maternal and Neonatal Tetanus."},{"key":"ref-4","article-title":"WHO | Maternal and Neonatal Tetanus Elimination (MNTE)."},{"key":"ref-5","doi-asserted-by":"publisher","first-page":"CD002959","DOI":"10.1002\/14651858.CD002959.pub4","article-title":"Vaccines for women for preventing neonatal tetanus.","author":"V Demicheli","year":"2015","journal-title":"Cochrane Database Syst Rev."},{"key":"ref-6","doi-asserted-by":"publisher","first-page":"171-80","DOI":"10.2147\/IJWH.S50539","article-title":"Maternal and neonatal tetanus elimination: from protecting women and newborns to protecting all.","volume":"7","author":"R Khan","year":"2015","journal-title":"Int J Womens Health."},{"key":"ref-7","doi-asserted-by":"publisher","first-page":"271-6","DOI":"10.1097\/01.qco.0000224822.65599.5b","article-title":"Prospects for prevention of childhood infections by maternal immunization.","volume":"19","author":"C Healy","year":"2006","journal-title":"Curr Opin Infect Dis."},{"key":"ref-8","doi-asserted-by":"publisher","first-page":"26-31","DOI":"10.4314\/eajph.v6i1.45739","article-title":"Tetanus toxoid vaccination coverage and differential between urban and rural areas of Bangladesh.","volume":"6","author":"M Rahman","year":"2009","journal-title":"East Afr J Public Health."},{"key":"ref-9","article-title":"WHO | Protection at birth (PAB) against tetanus."},{"key":"ref-10","article-title":"Enqu\u00eate D\u00e9mographique et de Sant\u00e9 du Cameroun 2018. 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Empirical evidence from Vietnam\u2019s Expanded Program on Immunization.","volume":"32","author":"M Mvundura","year":"2014","journal-title":"Vaccine."}],"container-title":["Gates Open Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/gatesopenresearch.org\/articles\/4-46\/v2\/xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/gatesopenresearch.org\/articles\/4-46\/v2\/pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/gatesopenresearch.org\/articles\/4-46\/v2\/iparadigms","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,12,27]],"date-time":"2024-12-27T04:15:12Z","timestamp":1735272912000},"score":1,"resource":{"primary":{"URL":"https:\/\/gatesopenresearch.org\/articles\/4-46\/v2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,3,10]]},"references-count":25,"URL":"https:\/\/doi.org\/10.12688\/gatesopenres.13105.2","relation":{"has-version":[{"id-type":"doi","id":"10.12688\/gatesopenres.13105.1","asserted-by":"subject"}],"has-review":[{"id-type":"doi","id":"10.21956\/gatesopenres.14440.r30778","asserted-by":"subject"},{"id-type":"doi","id":"10.21956\/gatesopenres.14440.r30781","asserted-by":"subject"},{"id-type":"doi","id":"10.21956\/gatesopenres.14440.r30777","asserted-by":"subject"},{"id-type":"doi","id":"10.21956\/gatesopenres.14440.r38969","asserted-by":"subject"},{"id-type":"doi","id":"10.21956\/gatesopenres.14440.r30777","asserted-by":"object"},{"id-type":"doi","id":"10.21956\/gatesopenres.14440.r30778","asserted-by":"object"},{"id-type":"doi","id":"10.21956\/gatesopenres.14440.r38969","asserted-by":"object"},{"id-type":"doi","id":"10.21956\/gatesopenres.14440.r30781","asserted-by":"object"}]},"ISSN":["2572-4754"],"issn-type":[{"value":"2572-4754","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,3,10]]},"assertion":[{"value":"Indexed","URL":"https:\/\/gatesopenresearch.org\/articles\/4-46\/v2#article-reports","order":0,"name":"referee-status","label":"Referee status","group":{"name":"current-referee-status","label":"Current Referee Status"}},{"value":"10.21956\/gatesopenres.14270.r28822, Jayani Pathirana, Medical Research Council, Respiratory and Meningeal Pathogens Research Unit, Faculty of Health Science, University of the Witwatersrand, Johannesburg, 11 Jun 2020, version 1, 2 approved with reservations","URL":"https:\/\/gatesopenresearch.org\/articles\/4-46\/v1#referee-response-28822","order":0,"name":"referee-response-28822","label":"Referee Report","group":{"name":"article-reports","label":"Article Reports"}},{"value":"<b>Igor NGUEGANG<\/b>; \n<i>Posted: 05 Nov 2020<\/i>; Thank you Sir Jayani Pathirana for the time you have taken to review the paper. Your suggestion will be taken into account. &nbsp; In response to your concerns, the study was conducted to access the Td vaccine community coverage because despite the good national coverage published, this region was victim of many epidemics situation of certain diseases under surveillance.  During the implementation, data were collected: &nbsp; &nbsp; - using a face-to-face method from women of childbearing age with at least one child, after obtaining the verbal authorization of their husband (according to the cultural reason of the study area) and the written consent of the women concerned. &nbsp; &nbsp; - from the&nbsp;antenatal care booklets or vaccination cards (depending of their availability at the health facilities) because, in our context, theses evidences of immunization are given to the women who are responsible for keeping them. &nbsp; &nbsp; - from maternal recall in case of absence of the previous document (undocumented immunization).&nbsp;  Cordially,","URL":"https:\/\/gatesopenresearch.org\/articles\/4-46\/v2#referee-comment-3377","order":1,"name":"referee-comment-3377","label":"Referee Comment","group":{"name":"article-reports","label":"Article Reports"}},{"value":"10.21956\/gatesopenres.14270.r29118, Ghose Bishwajt, Faculty of Social Sciences, School of International Development and Global Studies, University of Ottawa, Ottawa, ON, 14 Sep 2020, version 1, 2 approved with reservations","URL":"https:\/\/gatesopenresearch.org\/articles\/4-46\/v1#referee-response-29118","order":2,"name":"referee-response-29118","label":"Referee Report","group":{"name":"article-reports","label":"Article Reports"}},{"value":"<b>Igor NGUEGANG<\/b>; \n<i>Posted: 05 Nov 2020<\/i>; Thank you Sir&nbsp;Ghose Bishwajt for your critical reading and comments on this article; We will consider them when correcting.  Best,&nbsp;&nbsp;","URL":"https:\/\/gatesopenresearch.org\/articles\/4-46\/v2#referee-comment-3378","order":3,"name":"referee-comment-3378","label":"Referee Comment","group":{"name":"article-reports","label":"Article Reports"}},{"value":"10.21956\/gatesopenres.14440.r30777, Maria Ros\u00e1rio Fraga Oliveira Martins, Global Health and Tropical Medicine, Universidade Nova de Lisboa, Lisboa, 06 Jul 2021, version 2, indexed","URL":"https:\/\/gatesopenresearch.org\/articles\/4-46\/v2#referee-response-30777","order":4,"name":"referee-response-30777","label":"Referee Report","group":{"name":"article-reports","label":"Article Reports"}},{"value":"10.21956\/gatesopenres.14440.r30778, M. Carolina Danovaro-Holliday, Strategic Information Group, Expanded Program on Immunization (EPI), Department of Immunization, Vaccines and Biologicals (IVB), World Health Organization (WHO), Geneva, 12 Jul 2021, version 2, indexed","URL":"https:\/\/gatesopenresearch.org\/articles\/4-46\/v2#referee-response-30778","order":5,"name":"referee-response-30778","label":"Referee Report","group":{"name":"article-reports","label":"Article Reports"}},{"value":"10.21956\/gatesopenres.14440.r38969, Florence A. Kanu, Centers for Disease Control and Prevention, Atlanta, Georgia, 24 Dec 2024, version 2, indexed","URL":"https:\/\/gatesopenresearch.org\/articles\/4-46\/v2#referee-response-38969","order":6,"name":"referee-response-38969","label":"Referee Report","group":{"name":"article-reports","label":"Article Reports"}},{"value":"10.21956\/gatesopenres.14440.r30781, Karnaboopathy Ranganathan, Department of Community Medicine, Shri Sathya Sai Medical College and Research Institute, Kanchipuram, Tamil Nadu, 27 Dec 2024, version 2, indexed","URL":"https:\/\/gatesopenresearch.org\/articles\/4-46\/v2#referee-response-30781","order":7,"name":"referee-response-30781","label":"Referee Report","group":{"name":"article-reports","label":"Article Reports"}},{"value":"This work was supported by the Bill and Melinda Gates Foundation [OPP1190786]. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.","order":8,"name":"grant-information","label":"Grant Information"},{"value":"This is an open access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.","order":0,"name":"copyright-info","label":"Copyright"}]}}