{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T05:11:22Z","timestamp":1772169082756,"version":"3.50.1"},"update-to":[{"DOI":"10.12688\/hrbopenres.13500.1","type":"new_version","label":"New version","source":"publisher","updated":{"date-parts":[[2023,4,28]],"date-time":"2023-04-28T00:00:00Z","timestamp":1682640000000}}],"reference-count":24,"publisher":"F1000 Research Ltd","license":[{"start":{"date-parts":[[2023,4,28]],"date-time":"2023-04-28T00:00:00Z","timestamp":1682640000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100002081","name":"Irish Research Council","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100002081","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100023551","name":"Cystic Fibrosis Ireland","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100023551","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["hrbopenresearch.org"],"crossmark-restriction":false},"short-container-title":["HRB Open Res"],"abstract":"<ns4:p>\n                    <ns4:bold>Background<\/ns4:bold>\n                  <\/ns4:p>\n                  <ns4:p>Cystic Fibrosis (CF) is an autosomal recessive inherited multi-system disease that primarily affects the lungs and digestive system. New drug therapies and treatments are improving the lives of many people with CF. With improved life expectancy and increased quality of life, many people with CF are now contemplating parenthood and becoming pregnant, an aspiration that decades ago was almost unheard of. Given this quickly evolving and more positive health landscape, it is vital to understand how people with CF experience the care they receive whilst accessing and utilising fertility and maternity services. It is also important to explore the experiences of healthcare professionals involved in providing care during this period. The overall aim of the mixed-methods systematic review will be to explore the barriers and enablers experienced by people with CF and the healthcare professionals involved in their care in the pre-conception to post-partum period.<\/ns4:p>\n                  <ns4:p>\n                    <ns4:bold>\n                      Methods\n                      <ns4:italic\/>\n                    <\/ns4:bold>\n                  <\/ns4:p>\n                  <ns4:p>The proposed review will be conducted in accordance with the Joanna Briggs Institute (JBI) methodology for convergent integrated mixed methods systematic reviews. A systematic search of Medline (Ebsco), Cinahl, Embase, APA PsychINFO and Cochrane Library from inception to February 2022 will be conducted. Quantitative, qualitative and mixed methods studies pertaining to the experience of pre-conception to post-partum care for people with CF and their healthcare professionals will be included. Two independent reviewers will screen titles, abstracts and full texts with disagreements being resolved by a third reviewer.<\/ns4:p>\n                  <ns4:p>\n                    <ns4:bold>Conclusion<\/ns4:bold>\n                  <\/ns4:p>\n                  <ns4:p>This review will help to determine the potential barriers and facilitators experienced by people with Cystic Fibrosis and the health care professionals involved in their care during the pre-conception to post-partum period. The results will be of benefit specifically to the CF population and their healthcare providers when planning further studies in the area of fertility and pregnancy for this population and when delivering care.<\/ns4:p>","DOI":"10.12688\/hrbopenres.13500.2","type":"journal-article","created":{"date-parts":[[2023,4,28]],"date-time":"2023-04-28T08:00:14Z","timestamp":1682668814000},"page":"22","update-policy":"https:\/\/doi.org\/10.12688\/hrbopenres.crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Exploring the barriers and enablers experienced by people with Cystic Fibrosis and their healthcare professionals in accessing, utilising and delivering maternity and Cystic Fibrosis care during the pre-conception to post-partum period: A mixed methods systematic review protocol."],"prefix":"10.12688","volume":"5","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2834-7896","authenticated-orcid":false,"given":"Jen","family":"Balfe","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jennifer","family":"Donnelly","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sarah","family":"Tecklenborg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5312-5101","authenticated-orcid":false,"given":"Aisling","family":"Walsh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2560","published-online":{"date-parts":[[2023,4,28]]},"reference":[{"key":"ref-1","article-title":"Cystic Fibrosis foundation patient registry report","year":"2019"},{"key":"ref-2","article-title":"UK Cystic Fibrosis Registry Annual Data Report","year":"2019"},{"key":"ref-3","first-page":"438-440","article-title":"Pregnancy and Delivery in a Patient with Cystic Fibrosis of the Pancreas: Report of a case.","volume":"16","author":"B Siegel","year":"1960","journal-title":"Obstet Gynecol."},{"key":"ref-4","doi-asserted-by":"publisher","first-page":"213-219","DOI":"10.1513\/AnnalsATS.201211-108OC","article-title":"Long-term Effects of Pregnancy and Motherhood on Disease Outcomes of Women with Cystic Fibrosis.","volume":"10","author":"M Schechter","year":"2013","journal-title":"Ann Am Thorac Soc."},{"key":"ref-5","doi-asserted-by":"publisher","first-page":"S2-S32","DOI":"10.1016\/j.jcf.2007.10.001","article-title":"Guidelines for the management of pregnancy in women with cystic fibrosis.","volume":"7 Suppl 1","author":"F Edenborough","year":"2008","journal-title":"J Cyst Fibros."},{"key":"ref-6","doi-asserted-by":"publisher","first-page":"85-91","DOI":"10.1378\/chest.118.1.85","article-title":"Pregnancy in cystic fibrosis. 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Kalpakjian","year":"2021","journal-title":"Disabil Health J."},{"key":"ref-10","doi-asserted-by":"publisher","first-page":"170-174","DOI":"10.1136\/thx.50.2.170","article-title":"Outcome of pregnancy in women with cystic fibrosis.","volume":"50","author":"F Edenborough","year":"1995","journal-title":"Thorax."},{"key":"ref-11","doi-asserted-by":"publisher","first-page":"254-261","DOI":"10.1111\/j.1471-0528.2000.tb11697.x","article-title":"The outcome of 72 pregnancies in 55 women with cystic fibrosis in the United Kingdom 1977-1996.","volume":"107","author":"F Edenborough","year":"2000","journal-title":"BJOG."},{"key":"ref-12","doi-asserted-by":"publisher","first-page":"4-7","DOI":"10.3109\/14767058.2016.1161747","article-title":"Maternal co-morbidities and neonatal outcomes associated with cystic fibrosis.","volume":"30","author":"A Jelin","year":"2017","journal-title":"J Matern Fetal Neonatal 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status","group":{"name":"current-referee-status","label":"Current Referee Status"}},{"value":"10.21956\/hrbopenres.14992.r33695, Lyndsay A. Alexander, School of Health Sciences, Robert Gordon University, Aberdeen, 26 May 2023, version 2, indexed","URL":"https:\/\/hrbopenresearch.org\/articles\/5-22\/v2#referee-response-33695","order":0,"name":"referee-response-33695","label":"Referee Report","group":{"name":"article-reports","label":"Article Reports"}},{"value":"10.21956\/hrbopenres.14992.r33696, Emily M. Godfrey, Department of Family Medicine, University of Washington, Seattle, WA, 09 May 2023, version 2, indexed","URL":"https:\/\/hrbopenresearch.org\/articles\/5-22\/v2#referee-response-33696","order":1,"name":"referee-response-33696","label":"Referee Report","group":{"name":"article-reports","label":"Article Reports"}},{"value":"This review has been funded by the Irish Research Council as part of the Enterprise Partnership Scheme 2021 and is co-funded by Cystic Fibrosis Ireland.\n\nThis protocol has been developed with support from Cystic Fibrosis Ireland (CFI) and Dr Sarah Tecklenborg, senior research and policy officer with CFI is one of the authors. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.","order":2,"name":"grant-information","label":"Grant Information"},{"value":"This is an open access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.","order":0,"name":"copyright-info","label":"Copyright"}]}}