{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T08:48:14Z","timestamp":1791967694311,"version":"4.3.4"},"update-to":[{"DOI":"10.12688\/hrbopenres.14193.1","type":"new_version","label":"New version","source":"publisher","updated":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T00:00:00Z","timestamp":1777939200000}}],"reference-count":19,"publisher":"F1000 Research Ltd","license":[{"start":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T00:00:00Z","timestamp":1777939200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001634","name":"University of Galway","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001634","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["hrbopenresearch.org"],"crossmark-restriction":false},"short-container-title":["HRB Open Res"],"abstract":"<ns3:p>Background People experiencing homelessness face profound sexual health inequities, driven by overlapping structural vulnerabilities including housing instability, stigma, limited healthcare access, and social exclusion, as well as the complex lived realities associated with homelessness. Interventions designed to improve sexual health outcomes within this population are diverse, ranging from peer-led education to nurse-led clinical models and structural supports such as housing. However, the effectiveness of these interventions depends not only on their content but also on the contexts in which they are delivered and the circumstances of the populations they serve. A realist review seeks to understand how and why interventions work, for whom, and under what conditions by identifying context\u2013mechanism\u2013outcome configurations (CMOCs) that explain how outcomes are generated. Methods This review will follow Pawson\u2019s six-step realist synthesis methodology. An initial programme theory has been developed through preliminary literature searches and will be refined iteratively as new evidence is gathered. Published and grey literature will be systematically searched and selected for their relevance to developing and testing CMOCs. Data extraction will focus on identifying key information which can contribute to understanding contextual factors, mechanisms, and outcomes across intervention types. The synthesis will develop, refine, and test theories that explain how sexual health interventions produce change in varied contexts. Patient and public involvement contributors will be consulted throughout the review to validate findings and support interpretation. Conclusion This review will generate transferable insights into how sexual health interventions for people experiencing homelessness work across different contexts. By identifying mechanisms that generate outcomes, and the conditions that shape them, the findings will support more context-sensitive and effective policy, practice, and service design. The results will be disseminated through peer-reviewed publications, practitioner-facing summaries, and community-informed outputs.<\/ns3:p>","DOI":"10.12688\/hrbopenres.14193.2","type":"journal-article","created":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T08:04:07Z","timestamp":1791965047000},"page":"83","update-policy":"https:\/\/doi.org\/10.12688\/hrbopenres.crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Interventions to improve sexual health among the homeless community: a realist review protocol"],"prefix":"10.12688","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2783-1774","authenticated-orcid":false,"given":"Hau","family":"Nguyen","sequence":"first","affiliation":[{"name":"Galway County Galway University of 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The funding institution did not involve in developing this review protocol. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.","order":3,"name":"grant-information","label":"Grant Information"},{"value":"This is an open access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.","order":0,"name":"copyright-info","label":"Copyright"}]}}