{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,3]],"date-time":"2026-11-03T12:53:38Z","timestamp":1793710418776,"version":"4.6.1"},"reference-count":30,"publisher":"F1000 Research Ltd","license":[{"start":{"date-parts":[[2017,10,17]],"date-time":"2017-10-17T00:00:00Z","timestamp":1508198400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100004440","name":"Wellcome Trust","doi-asserted-by":"publisher","award":["104490"],"award-info":[{"award-number":["104490"]}],"id":[{"id":"10.13039\/100004440","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["wellcomeopenresearch.org"],"crossmark-restriction":false},"short-container-title":["Wellcome Open Res"],"abstract":"<ns4:p>\n                    <ns4:bold>Background:<\/ns4:bold>\n                    There is a paucity of evidence regarding long-term outcomes of late preterm (34-36 weeks) and early term (37-38 weeks) delivery.\u00a0 The objective of this systematic review was to assess long-term cognitive outcomes of children born at these gestations.\n                  <\/ns4:p>\n                  <ns4:p>\n                    <ns4:bold>Methods:<\/ns4:bold>\n                    Four electronic databases (Medline, Embase, clinicaltrials.gov and PsycINFO) were searched.\u00a0 Last search was 5\n                    <ns4:sup>th<\/ns4:sup>\n                    August 2016.\n                    <ns4:bold>\u00a0<\/ns4:bold>\n                    Studies were included if they reported gestational age, IQ measure and the ages assessed.\u00a0 The protocol was registered with the International prospective register of systematic reviews (PROSPERO Record\n                    <ns4:ext-link xmlns:ns3=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" ns3:href=\"https:\/\/www.crd.york.ac.uk\/PROSPERO\/display_record.asp?ID=CRD42015015472\">CRD42015015472<\/ns4:ext-link>\n                    ).\u00a0 Two independent reviewers assessed the studies.\u00a0 Data were abstracted and critical appraisal performed of eligible papers.\n                  <\/ns4:p>\n                  <ns4:p>\n                    <ns4:bold>Results:<\/ns4:bold>\n                    Of 11,905 potential articles, seven studies reporting on 41,344 children were included.\u00a0 For early term births, four studies (n = 35,711) consistently showed an increase in cognitive scores for infants born at full term (39-41 weeks) compared to those born at early term (37-38 weeks) with increases for each week of term (difference between 37 and 40 weeks of around 3 IQ points), despite differences in age of testing and method of IQ\/cognitive testing.\u00a0 Four studies (n = 5644) reporting childhood cognitive outcomes of late preterm births (34 \u2013 36 weeks) also differed in study design (cohort and case control); age of testing; and method of IQ testing, and found no differences in outcomes between late preterm and term births, although risk of bias was high in included studies.\n                  <\/ns4:p>\n                  <ns4:p>\n                    <ns4:bold>Conclusion:\u00a0<\/ns4:bold>\n                    Children born at 39-41 weeks have higher cognitive outcome scores compared to those born at early term (37-38 weeks).\u00a0 This should be considered when discussing timing of delivery.\u00a0 For children born late preterm, the data is scarce and when compared to full term (37-42 weeks) did not show any difference in IQ scores.\n                  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1","author":"H Blencowe","year":"2013","journal-title":"Reprod Health."},{"key":"ref-3","doi-asserted-by":"publisher","first-page":"246-8","DOI":"10.1053\/j.semperi.2011.05.013","article-title":"The scope of the problem: the epidemiology of late preterm and early-term birth.","volume":"35","author":"C Gyamfi-Bannerman","year":"2011","journal-title":"Semin Perinatol."},{"key":"ref-4","doi-asserted-by":"publisher","first-page":"780-1","DOI":"10.1097\/01.ogx.0000363249.47533.8e","article-title":"Delivery indications at late-preterm gestations and infant mortality rates in the United States.","volume":"64","author":"U Reddy","year":"2009","journal-title":"Obstet Gynecol Surv."},{"key":"ref-5","doi-asserted-by":"publisher","first-page":"739-51","DOI":"10.1016\/j.clp.2013.07.006","article-title":"Long-term outcomes of moderately preterm, late preterm, and early term infants.","volume":"40","author":"B Vohr","year":"2013","journal-title":"Clin Perinatol."},{"key":"ref-6","doi-asserted-by":"publisher","first-page":"39-44","DOI":"10.1016\/j.anpedi.2013.10.015","article-title":"[Neonatal morbidity in early-term newborns].","volume":"81","author":"S Mart\u00ednez-Nadal","year":"2014","journal-title":"An Pediatr (Barc)."},{"key":"ref-7","article-title":"Greentop Guideline No. 7.: Antenatal Corticosteroids to Reduce Neonatal Morbidity and Mortality.","year":"2010","journal-title":"London: RCOG."},{"key":"ref-8","doi-asserted-by":"publisher","first-page":"904-907","DOI":"10.1097\/01.AOG.0000428647.67925.d3","article-title":"ACOG committee opinion no. 559: Cesarean delivery on maternal request.","volume":"121","year":"2013","journal-title":"Obstet Gynecol."},{"key":"ref-9","doi-asserted-by":"publisher","first-page":"e1000289","DOI":"10.1371\/journal.pmed.1000289","article-title":"Gestational age at delivery and special educational need: retrospective cohort study of 407,503 schoolchildren.","volume":"7","author":"D MacKay","year":"2010","journal-title":"PLoS Med."},{"key":"ref-10","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3389\/fpsyg.2011.00001","article-title":"Children's Brain Development Benefits from Longer Gestation.","volume":"2","author":"E Davis","year":"2011","journal-title":"Front Psychol."},{"key":"ref-11","doi-asserted-by":"publisher","first-page":"e7961","DOI":"10.1136\/bmj.e7961","article-title":"Neurological and developmental outcome in extremely preterm children born in England in 1995 and 2006: the EPICure studies.","volume":"345","author":"T Moore","year":"British Medical Journal Publishing Group; 2012","journal-title":"BMJ."},{"key":"ref-12","doi-asserted-by":"publisher","first-page":"e7976","DOI":"10.1136\/bmj.e7976","article-title":"Short term outcomes after extreme preterm birth in England: comparison of two birth cohorts in 1995 and 2006 (the EPICure studies).","volume":"345","author":"K Costeloe","year":"British Medical Journal Publishing Group; 2012","journal-title":"BMJ."},{"key":"ref-13","doi-asserted-by":"publisher","first-page":"167-78","DOI":"10.1002\/(SICI)1096-9861(19971020)387:2<167::AID-CNE1>3.0.CO;2-Z","article-title":"Regional differences in synaptogenesis in human cerebral cortex.","volume":"387","author":"P Huttenlocher","year":"1997","journal-title":"J Comp Neurol."},{"key":"ref-14","doi-asserted-by":"publisher","first-page":"374.e1-374.e9","DOI":"10.1016\/j.ajog.2011.07.015","article-title":"A systematic review of severe morbidity in infants born late preterm.","volume":"205","author":"M Teune","year":"2011","journal-title":"Am J Obstet Gynecol."},{"key":"ref-15","doi-asserted-by":"publisher","first-page":"344-9","DOI":"10.1016\/j.jclinepi.2007.11.008","article-title":"The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: guidelines for reporting observational studies.","volume":"61","author":"E von Elm","year":"2008","journal-title":"J Clin Epidemiol."},{"key":"ref-16","doi-asserted-by":"publisher","first-page":"264-9, W64","DOI":"10.7326\/0003-4819-151-4-200908180-00135","article-title":"Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement.","volume":"151","author":"D Moher","year":"2009","journal-title":"Ann Intern Med."},{"key":"ref-17","doi-asserted-by":"publisher","first-page":"408-14","DOI":"10.1016\/j.jclinepi.2012.09.016","article-title":"Testing a tool for assessing the risk of bias for nonrandomized studies showed moderate reliability and promising validity.","volume":"66","author":"S Kim","year":"2013","journal-title":"J Clin Epidemiol."},{"key":"ref-18","doi-asserted-by":"publisher","first-page":"e113758","DOI":"10.1371\/journal.pone.0113758","article-title":"Longer gestation among children born full term influences cognitive and motor development.","volume":"9","author":"E Espel","year":"2014","journal-title":"PLoS One."},{"key":"ref-19","doi-asserted-by":"publisher","first-page":"e1475-81","DOI":"10.1542\/peds.2012-3215","article-title":"Developmental scores at 1 year with increasing gestational age, 37\u201341 weeks.","volume":"131","author":"O Rose","year":"2013","journal-title":"Pediatrics."},{"key":"ref-20","doi-asserted-by":"publisher","first-page":"399-406","DOI":"10.1093\/aje\/kwp413","article-title":"Variation in child cognitive ability by week of gestation among healthy term births.","volume":"171","author":"S Yang","year":"2010","journal-title":"Am J Epidemiol."},{"key":"ref-21","doi-asserted-by":"publisher","first-page":"S342-3","DOI":"10.1016\/j.ajog.2013.10.729","article-title":"696: Long-term neurodevelopmental outcomes of late preterm and early term neonates.","volume":"210","author":"C Gyamfi-Bannerman","year":"2014","journal-title":"Am J Obstet Gynecol."},{"key":"ref-22","doi-asserted-by":"publisher","first-page":"1612-24","DOI":"10.1007\/s10995-011-0853-2","article-title":"Developmental outcomes of late-preterm infants at 2 and 4 years.","volume":"16","author":"L Nepomnyaschy","year":"2012","journal-title":"Matern Child Health J."},{"key":"ref-23","doi-asserted-by":"publisher","first-page":"518-23","DOI":"10.1016\/j.ejpn.2016.04.011","article-title":"Early psychomotor development of low-risk preterm infants: Influence of gestational age and gender.","volume":"20","author":"D Romeo","year":"2016","journal-title":"Eur J Paediatr Neurol."},{"key":"ref-24","doi-asserted-by":"publisher","first-page":"761-5","DOI":"10.1177\/0883073807304006","article-title":"Gestational age at preterm birth in relation to corpus callosum and general cognitive outcome in adolescents.","volume":"22","author":"A Narberhaus","year":"2007","journal-title":"J Child Neurol."},{"key":"ref-25","doi-asserted-by":"publisher","first-page":"347-349","DOI":"10.1017\/S0033291700014422","article-title":"Neuropsychological Assessment By Muriel Lezak. Oxford University Press: London. 1976.","volume":"8","author":"D Benson","year":"1978","journal-title":"Psychol Med."},{"key":"ref-26","doi-asserted-by":"publisher","first-page":"146-58","DOI":"10.1016\/j.intell.2017.02.001","article-title":"Birth weight and cognitive ability in adulthood: A systematic review and meta-analysis.","volume":"61","author":"B Grove","year":"2017","journal-title":"Intelligence."},{"key":"ref-27","doi-asserted-by":"publisher","first-page":"758-64","DOI":"10.1001\/jamapediatrics.2016.0238","article-title":"Long-term Cognitive and Health Outcomes of School-Aged Children Who Were Born Late-Term vs Full-Term.","volume":"170","author":"D Figlio","year":"2016","journal-title":"JAMA Pediatr."},{"key":"ref-28","doi-asserted-by":"publisher","first-page":"1303-11","DOI":"10.1111\/1471-0528.13324","article-title":"A whole-of-population study of term and post-term gestational age at birth and children's development.","volume":"122","author":"L Smithers","year":"2015","journal-title":"BJOG."},{"key":"ref-29","doi-asserted-by":"publisher","first-page":"297-312","DOI":"10.1111\/cch.12320","article-title":"Long-term cognitive and school outcomes of late-preterm and early-term births: a systematic review.","volume":"42","author":"E Chan","year":"2016","journal-title":"Child Care Health Dev."},{"key":"ref-30","doi-asserted-by":"publisher","first-page":"489.e1-7","DOI":"10.1016\/j.ajog.2006.11.017","article-title":"Umbilical blood flow during pregnancy: evidence for decreasing placental perfusion.","volume":"196","author":"G Link","year":"2007","journal-title":"Am J Obstet Gynecol."}],"container-title":["Wellcome Open Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/wellcomeopenresearch.org\/articles\/2-101\/v1\/xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/wellcomeopenresearch.org\/articles\/2-101\/v1\/pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/wellcomeopenresearch.org\/articles\/2-101\/v1\/iparadigms","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,2,20]],"date-time":"2019-02-20T16:35:15Z","timestamp":1550680515000},"score":1,"resource":{"primary":{"URL":"https:\/\/wellcomeopenresearch.org\/articles\/2-101\/v1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,10,17]]},"references-count":30,"URL":"https:\/\/doi.org\/10.12688\/wellcomeopenres.12783.1","relation":{"has-review":[{"id-type":"doi","id":"10.21956\/wellcomeopenres.13850.r27305","asserted-by":"subject"},{"id-type":"doi","id":"10.21956\/wellcomeopenres.13850.r27478","asserted-by":"subject"},{"id-type":"doi","id":"10.21956\/wellcomeopenres.13850.r27265","asserted-by":"subject"},{"id-type":"doi","id":"10.21956\/wellcomeopenres.13850.r27265","asserted-by":"object"},{"id-type":"doi","id":"10.21956\/wellcomeopenres.13850.r27478","asserted-by":"object"},{"id-type":"doi","id":"10.21956\/wellcomeopenres.13850.r27305","asserted-by":"object"}]},"ISSN":["2398-502X"],"issn-type":[{"value":"2398-502X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,10,17]]},"assertion":[{"value":"Indexed","URL":"https:\/\/wellcomeopenresearch.org\/articles\/2-101\/v1#article-reports","order":0,"name":"referee-status","label":"Referee status","group":{"name":"current-referee-status","label":"Current Referee Status"}},{"value":"10.21956\/wellcomeopenres.13850.r27265, Jennifer M. Walsh, Murdoch Children\u2019s Research Institute, Melbourne, Vic, Australia, 20 Nov 2017, version 1, indexed","URL":"https:\/\/wellcomeopenresearch.org\/articles\/2-101\/v1#referee-response-27265","order":0,"name":"referee-response-27265","label":"Referee Report","group":{"name":"article-reports","label":"Article Reports"}},{"value":"10.21956\/wellcomeopenres.13850.r27305, Marjolein Kok, Academic Medical Center, Department of Obstetrics and Gynecology, University of Amsterdam, Amsterdam, The Netherlands, 20 Nov 2017, version 1, indexed","URL":"https:\/\/wellcomeopenresearch.org\/articles\/2-101\/v1#referee-response-27305","order":1,"name":"referee-response-27305","label":"Referee Report","group":{"name":"article-reports","label":"Article Reports"}},{"value":"10.21956\/wellcomeopenres.13850.r27478, Nana Hyldig, Gitte Zachariassen, Hans Christian Andersens Hospital, Odense University Hospital, University of Southern Denmark, Odense, Denmark, 07 Dec 2017, version 1, indexed","URL":"https:\/\/wellcomeopenresearch.org\/articles\/2-101\/v1#referee-response-27478","order":2,"name":"referee-response-27478","label":"Referee Report","group":{"name":"article-reports","label":"Article Reports"}},{"value":"This work was supported by a Wellcome Trust PhD studentship [104490] to Sarah Murray.","order":3,"name":"grant-information","label":"Grant Information"},{"value":"This is an open access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.","order":0,"name":"copyright-info","label":"Copyright"}]}}