{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T19:26:54Z","timestamp":1782847614531,"version":"3.54.5"},"update-to":[{"DOI":"10.12688\/wellcomeopenres.17530.1","type":"new_version","label":"New version","source":"publisher","updated":{"date-parts":[[2023,11,7]],"date-time":"2023-11-07T00:00:00Z","timestamp":1699315200000}}],"reference-count":54,"publisher":"F1000 Research Ltd","license":[{"start":{"date-parts":[[2023,11,7]],"date-time":"2023-11-07T00:00:00Z","timestamp":1699315200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000265","name":"Medical Research Council","doi-asserted-by":"publisher","award":["MR\/T040327\/1"],"award-info":[{"award-number":["MR\/T040327\/1"]}],"id":[{"id":"10.13039\/501100000265","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Charlize Theron Africa Outreach Project"},{"name":"Swiss Development Corporation"},{"DOI":"10.13039\/100010269","name":"Wellcome Trust","doi-asserted-by":"crossref","award":["206316"],"award-info":[{"award-number":["206316"]}],"id":[{"id":"10.13039\/100010269","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["wellcomeopenresearch.org"],"crossmark-restriction":false},"short-container-title":["Wellcome Open Res"],"abstract":"<ns3:p>Background Youth have poorer HIV-related outcomes when compared to other age-groups. We describe the protocol for a cluster randomised trial (CRT) to evaluate the effectiveness of community-based, integrated HIV and sexual and reproductive health services for youth on HIV outcomes. Protocol The CHIEDZA trial is being conducted in three provinces in Zimbabwe, each with eight geographically demarcated areas (clusters) (total 24 clusters) randomised 1:1 to standard of care (existing health services) or to the intervention. The intervention comprises community-based delivery of HIV services including testing, antiretroviral therapy, treatment monitoring and adherence support as well as family planning, syndromic management of sexually transmitted infections (STIs), menstrual health management, condoms and HIV prevention and general health counselling. Youth aged 16\u201324 years living within intervention clusters are eligible to access CHIEDZA services. A CRT of STI screening (chlamydia, gonorrhoea and trichomoniasis) is nested in two provinces (16 of 24 clusters). The intervention is delivered over a 30-month period by a multidisciplinary team trained and configured to provide high-quality, youth friendly services. Outcomes will be ascertained through a population-based survey of 18\u201324-year-olds. The primary outcome is HIV viral load &lt;1000 copies\/ml in those living with HIV and proportion who test positive for STIs (for the nested trial). A detailed process and cost evaluation of the trial will be conducted. Ethics and Dissemination The trial protocol was approved by the Medical Research Council of Zimbabwe, the Biomedical Research and Training Institute Institutional Review Board and the London School of Hygiene &amp; Tropical Medicine Research Ethics Committee. Results will be submitted to open-access peer-reviewed journals, presented at academic meetings and shared with participating communities and with national and international policy-making bodies. Trial Registration https:\/\/clinicaltrials.gov\/: NCT03719521<\/ns3:p>","DOI":"10.12688\/wellcomeopenres.17530.2","type":"journal-article","created":{"date-parts":[[2023,11,7]],"date-time":"2023-11-07T11:25:52Z","timestamp":1699356352000},"page":"54","update-policy":"https:\/\/doi.org\/10.12688\/wellcomeopenres.crossmark-policy","source":"Crossref","is-referenced-by-count":6,"title":["The impact of community-based integrated HIV and sexual and reproductive health services for youth on population-level HIV viral load and sexually transmitted infections in Zimbabwe: protocol for the CHIEDZA cluster-randomised trial"],"prefix":"10.12688","volume":"7","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1617-3603","authenticated-orcid":false,"given":"Chido","family":"Dziva Chikwari","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ethel","family":"Dauya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0066-8345","authenticated-orcid":false,"given":"Tsitsi","family":"Bandason","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mandikudza","family":"Tembo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Constancia","family":"Mavodza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4897-458X","authenticated-orcid":false,"given":"Victoria","family":"Simms","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9725-7931","authenticated-orcid":false,"given":"Constance RS.","family":"Mackworth-Young","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tsitsi","family":"Apollo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7042-2394","authenticated-orcid":false,"given":"Chris","family":"Grundy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3547-7936","authenticated-orcid":false,"given":"Helen","family":"Weiss","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katharina","family":"Kranzer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tino","family":"Mavimba","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pitchaya","family":"Indravudh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aoife","family":"Doyle","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Owen","family":"Mugurungi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Machiha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7628-8408","authenticated-orcid":false,"given":"Sarah","family":"Bernays","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6334-0318","authenticated-orcid":false,"given":"Joanna","family":"Busza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernard","family":"Madzima","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1693-5196","authenticated-orcid":false,"given":"Fern","family":"Terris-Prestholt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9902-6248","authenticated-orcid":false,"given":"Ona","family":"McCarthy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard","family":"Hayes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suzanna","family":"Francis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7660-9176","authenticated-orcid":false,"given":"Rashida A.","family":"Ferrand","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2560","published-online":{"date-parts":[[2023,11,7]]},"reference":[{"key":"ref-1","article-title":"UNAIDS Data.","year":"2020"},{"key":"ref-2","doi-asserted-by":"publisher","first-page":"170-8","DOI":"10.1097\/COH.0000000000000449","article-title":"The global epidemiology of adolescents living with HIV: time for more granular data to improve adolescent health outcomes.","volume":"13","author":"A Slogrove","year":"2018","journal-title":"Curr Opin HIV AIDS."},{"key":"ref-3","article-title":"Zambia Population-based HIV Impact Assessment (ZAMPHIA) 2016: First Report.","year":"2017"},{"key":"ref-4","article-title":"Malawi Population-based HIV Impact Assessment (MPHIA) 2015-16: First Report.","year":"2017"},{"key":"ref-5","article-title":"Zimbabwe Population-based HIV Impact Assessment (ZIMPHIA) 2015-16: First Report.","year":"2017"},{"key":"ref-6","doi-asserted-by":"publisher","first-page":"921-9","DOI":"10.1056\/NEJM200003303421303","article-title":"Viral Load and Heterosexual Transmission of Human Immunodeficiency Virus Type 1. Rakai Project Study Group.","volume":"342","author":"T Quinn","year":"2000","journal-title":"N Engl J Med."},{"key":"ref-7","doi-asserted-by":"publisher","first-page":"257-64","DOI":"10.1097\/COH.0000000000000452","article-title":"Barriers to, and emerging strategies for, HIV testing among adolescents in sub-Saharan Africa.","volume":"13","author":"C Chikwari","year":"2018","journal-title":"Curr Opin HIV AIDS."},{"key":"ref-8","doi-asserted-by":"publisher","first-page":"45","DOI":"10.21037\/mhealth.2019.09.02","article-title":"Barriers to HIV care and adherence for young people living with HIV in Zambia and mHealth.","volume":"5","author":"N St Clair-Sullivan","year":"2019","journal-title":"Mhealth."},{"key":"ref-9","doi-asserted-by":"publisher","first-page":"S40-S2","DOI":"10.1016\/j.ijgo.2015.02.006","article-title":"Adolescent sexual and reproductive health: The global challenges.","volume":"131 Suppl 1","author":"J Morris","year":"2015","journal-title":"Int J Gynaecol Obstet."},{"key":"ref-10","doi-asserted-by":"publisher","first-page":"132-6","DOI":"10.1016\/j.ijgo.2009.03.025","article-title":"Access to sexual and reproductive health for young people: bridging the disconnect between rights and reality.","volume":"106","author":"D Shaw","year":"2009","journal-title":"Int J Gynaecol Obstet."},{"key":"ref-11","doi-asserted-by":"publisher","first-page":"174-82","DOI":"10.1136\/sti.2002.004101","article-title":"Approaches to the control of sexually transmitted infections in developing countries: old problems and modern challenges.","volume":"80","author":"P Mayaud","year":"2004","journal-title":"Sex Transm Infect."},{"key":"ref-12","doi-asserted-by":"publisher","first-page":"137-43","DOI":"10.1097\/MOP.0000000000000578","article-title":"The growing epidemic of sexually transmitted infections in adolescents: a neglected population.","volume":"30","author":"C Shannon","year":"2018","journal-title":"Curr Opin Pediatr."},{"key":"ref-13","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0196209","article-title":"Beyond syndromic management: Opportunities for diagnosis-based treatment of sexually transmitted infections in low- and middle-income countries.","volume":"13","author":"N Garrett","year":"2018","journal-title":"PLoS One."},{"key":"ref-14","doi-asserted-by":"publisher","first-page":"531-9","DOI":"10.1177\/0956462417740487","article-title":"Converging epidemics of sexually transmitted infections and bacterial vaginosis in southern African female adolescents at risk of HIV.","volume":"29","author":"S Barnabas","year":"2018","journal-title":"Int J STD AIDS."},{"key":"ref-15","doi-asserted-by":"publisher","first-page":"ii28-30","DOI":"10.1136\/sti.2010.047647","article-title":"Applying new technologies for diagnosing sexually transmitted infections in resource-poor settings.","volume":"87 Suppl 2","author":"R Peeling","year":"2011","journal-title":"Sex Transm Infect."},{"key":"ref-16","doi-asserted-by":"publisher","first-page":"53","DOI":"10.12688\/wellcomeopenres.17531.1","article-title":"Putting youth at the centre: co-design of a community-based intervention to improve HIV outcomes among youth in Zimbabwe [version 1; peer review: 1 approved with reservations].","volume":"7","author":"C Mackworth-Young","year":"2022","journal-title":"Wellcome Open Res."},{"key":"ref-17","doi-asserted-by":"publisher","first-page":"237-52","DOI":"10.1089\/apc.2018.0320","article-title":"Recent Interventions to Improve Retention in HIV Care and Adherence to Antiretroviral Treatment Among Adolescents and Youth: A Systematic Review.","volume":"33","author":"M Casale","year":"2019","journal-title":"AIDS Patient Care STDS."},{"key":"ref-18","doi-asserted-by":"publisher","first-page":"S22-S41","DOI":"10.1016\/j.jadohealth.2014.09.012","article-title":"Effective Strategies to Provide Adolescent Sexual and Reproductive Health Services and to Increase Demand and Community Support.","volume":"56","author":"D Denno","year":"2015","journal-title":"J Adolesc Health."},{"key":"ref-19","doi-asserted-by":"publisher","DOI":"10.1186\/s12978-021-01183-y","article-title":"Factors influencing access to and utilisation of youth-friendly sexual and reproductive health services in sub-Saharan Africa: a systematic review.","volume":"18","author":"L Ninsiima","year":"2021","journal-title":"Reprod Health."},{"key":"ref-20","article-title":"90-90-90. An ambitious treatment target to help end the AIDS epidemic.","year":"2014"},{"key":"ref-21","article-title":"Zimbabwe Population Census Report 2012.","year":"2012"},{"key":"ref-22","article-title":"OpenStreetMap."},{"key":"ref-23","article-title":"MAPS.ME","year":"2021"},{"key":"ref-24","article-title":"\u201cNothing about us without us\u201d: the participation and partnership of youth in co-designing a community-based HIV intervention in Zimbabwe.","author":"S Dringus","year":"2019"},{"key":"ref-25","doi-asserted-by":"publisher","first-page":"577","DOI":"10.4081\/jphr.2015.577","article-title":"Framework for Selecting Best Practices in Public Health: A Systematic Literature Review.","volume":"4","author":"E Ng","year":"2015","journal-title":"J Public Health Res."},{"key":"ref-26","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.1001102","article-title":"The uptake and accuracy of oral kits for HIV self-testing in high HIV prevalence setting: a cross-sectional feasibility study in Blantyre, Malawi.","volume":"8","author":"A Choko","year":"2011","journal-title":"PLoS Med."},{"key":"ref-27","doi-asserted-by":"publisher","first-page":"372-9","DOI":"10.1001\/jama.2014.6493","article-title":"Effect of optional home initiation of HIV care following HIV self-testing on antiretroviral therapy initiation among adults in Malawi: a randomized clinical trial.","volume":"312","author":"P MacPherson","year":"2014","journal-title":"JAMA."},{"key":"ref-28","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.1002015","article-title":"Initiating Antiretroviral Therapy for HIV at a Patient's First Clinic Visit: The RapIT Randomized Controlled Trial.","volume":"13","author":"S Rosen","year":"2016","journal-title":"PLoS Med."},{"key":"ref-29","article-title":"Guidelines for Antiretroviral Therapy for the Prevention and Treatment of HIV in Zimbabwe.","year":"2016"},{"key":"ref-30","doi-asserted-by":"publisher","first-page":"e68-e76","DOI":"10.1016\/S2352-3018(14)70024-4","article-title":"Initiation of antiretroviral therapy and viral suppression after home HIV testing and counselling in KwaZulu-Natal, South Africa, and Mbarara district, Uganda: a prospective, observational intervention study.","volume":"1","author":"R Barnabas","year":"2014","journal-title":"Lancet HIV."},{"key":"ref-31","doi-asserted-by":"publisher","DOI":"10.7448\/IAS.18.2.19833","article-title":"Providing comprehensive health services for young key populations: needs, barriers and gaps.","volume":"18","author":"S Delany-Moretlwe","year":"2015","journal-title":"J Int AIDS Soc."},{"key":"ref-32","doi-asserted-by":"publisher","first-page":"13-4","DOI":"10.1016\/S0140-6736(04)16611-7","article-title":"Social marketing of condoms is great, but we need more free condoms.","volume":"364","author":"D Cohen","year":"2004","journal-title":"Lancet."},{"key":"ref-33","doi-asserted-by":"publisher","first-page":"360-71","DOI":"10.1016\/j.amepre.2014.05.034","article-title":"Mass media health communication campaigns combined with health-related product distribution: a community guide systematic review.","volume":"47","author":"M Robinson","year":"2014","journal-title":"Am J Prev Med."},{"key":"ref-34","doi-asserted-by":"publisher","DOI":"10.1186\/s12889-018-5477-7","article-title":"Development of an intervention delivered by mobile phone aimed at decreasing unintended pregnancy among young people in three lower middle income countries.","volume":"18","author":"O McCarthy","year":"2018","journal-title":"BMC Public Health."},{"key":"ref-35","doi-asserted-by":"publisher","DOI":"10.2196\/14073","article-title":"An Intervention Delivered by Mobile Phone Instant Messaging to Increase Acceptability and Use of Effective Contraception Among Young Women in Bolivia: Randomized Controlled Trial.","volume":"22","author":"O McCarthy","year":"2020","journal-title":"J Med Internet Res."},{"key":"ref-36","doi-asserted-by":"publisher","DOI":"10.1186\/s13063-019-3297-4","article-title":"A randomized controlled trial of an intervention delivered by mobile phone text message to increase the acceptability of effective contraception among young women in Palestine.","volume":"20","author":"O McCarthy","year":"2019","journal-title":"Trials."},{"key":"ref-37","doi-asserted-by":"publisher","DOI":"10.1186\/s12978-018-0473-z","article-title":"A randomized controlled trial of an intervention delivered by mobile phone app instant messaging to increase the acceptability of effective contraception among young people in Tajikistan.","volume":"15","author":"O McCarthy","year":"2018","journal-title":"Reprod Health."},{"key":"ref-38","article-title":"Adapting an evidence-based contraceptive behavioural intervention delivered by mobile phone for young people in Zimbabwe","author":"O McCarthy","year":"2021"},{"key":"ref-39","doi-asserted-by":"publisher","first-page":"297-312","DOI":"10.1080\/17437199.2015.1077155","article-title":"A Taxonomy of Behaviour Change Methods: an Intervention Mapping Approach.","volume":"10","author":"G Kok","year":"2016","journal-title":"Health Psychol Rev."},{"key":"ref-40","doi-asserted-by":"publisher","DOI":"10.1186\/s12978-015-0009-8","article-title":"Putting menarche and girls into the global population health agenda.","volume":"12","author":"M Sommer","year":"2015","journal-title":"Reprod Health."},{"key":"ref-41","doi-asserted-by":"publisher","first-page":"469-75","DOI":"10.1111\/j.1600-0447.1997.tb10134.x","article-title":"The Shona Symptom Questionnaire: the development of an indigenous measure of common mental disorders in Harare.","volume":"95","author":"V Patel","year":"1997","journal-title":"Acta Psychiatr Scand."},{"key":"ref-42","doi-asserted-by":"publisher","DOI":"10.1186\/s12942-015-0026-4","article-title":"Using remote, spatial techniques to select a random household sample in a dispersed, semi-nomadic pastoral community: utility for a longitudinal health and demographic surveillance system.","volume":"14","author":"A Pearson","year":"2015","journal-title":"Int J Health Geogr."},{"key":"ref-43","article-title":"ArcGIS Online","year":"2021"},{"key":"ref-44","doi-asserted-by":"publisher","first-page":"338","DOI":"10.1201\/9781584888178","article-title":"Cluster Randomised Trials.","author":"R Hayes","year":"2009"},{"key":"ref-45","doi-asserted-by":"publisher","first-page":"257-65","DOI":"10.1001\/jama.2021.9941","article-title":"Guidelines for Reporting Trial Protocols and Completed Trials Modified Due to the COVID-19 Pandemic and Other Extenuating Circumstances: The CONSERVE 2021 Statement.","volume":"326","author":"A Orkin","year":"2021","journal-title":"JAMA."},{"key":"ref-46","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.h1258","article-title":"Process evaluation of complex interventions: Medical Research Council guidance.","volume":"350","author":"G Moore","year":"2015","journal-title":"BMJ."},{"key":"ref-47","doi-asserted-by":"publisher","first-page":"3-20","DOI":"10.1177\/1525822X05282260","article-title":"Using Mixed-Methods Sequential Explanatory Design: From Theory to Practice.","volume":"18","author":"N Ivankova","year":"2006","journal-title":"Field Methods."},{"key":"ref-48","article-title":"Designing and conducting mixed methods research.","author":"J Creswell","year":"2011"},{"key":"ref-49","article-title":"Reference Case for Estimating the Costs of Global Health Services and Interventions.","author":"A Vassall","year":"2017"},{"key":"ref-50","article-title":"Differneiated Service Delivery","year":"2021"},{"key":"ref-51","doi-asserted-by":"publisher","first-page":"1397-404","DOI":"10.1097\/QAD.0b013e32832b7dca","article-title":"Sexual transmission of HIV according to viral load and antiretroviral therapy: systematic review and meta-analysis.","volume":"23","author":"S Attia","year":"2009","journal-title":"Aids."},{"key":"ref-52","doi-asserted-by":"publisher","first-page":"493-505","DOI":"10.1056\/NEJMoa1105243","article-title":"Prevention of HIV-1 infection with early antiretroviral therapy.","volume":"365","author":"M Cohen","year":"2011","journal-title":"N Engl J Med."},{"key":"ref-53","doi-asserted-by":"publisher","first-page":"2618-26","DOI":"10.1001\/jama.2016.19102","article-title":"Effect of a Primary Care-Based Psychological Intervention on Symptoms of Common Mental Disorders in Zimbabwe: A Randomized Clinical Trial.","volume":"316","author":"D Chibanda","year":"2016","journal-title":"JAMA."},{"key":"ref-54","article-title":"Other risks don't stop': adapting a youth sexual and reproductive health intervention in Zimbabwe during COVID-19.","author":"C Mackworth-Young","year":"2021"}],"container-title":["Wellcome Open Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/wellcomeopenresearch.org\/articles\/7-54\/v2\/xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/wellcomeopenresearch.org\/articles\/7-54\/v2\/pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/wellcomeopenresearch.org\/articles\/7-54\/v2\/iparadigms","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,12,28]],"date-time":"2023-12-28T00:55:14Z","timestamp":1703724914000},"score":1,"resource":{"primary":{"URL":"https:\/\/wellcomeopenresearch.org\/articles\/7-54\/v2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,11,7]]},"references-count":54,"URL":"https:\/\/doi.org\/10.12688\/wellcomeopenres.17530.2","relation":{"has-review":[{"id-type":"doi","id":"10.21956\/wellcomeopenres.22528.r69785","asserted-by":"subject"},{"id-type":"doi","id":"10.21956\/wellcomeopenres.22528.r69785","asserted-by":"object"}]},"ISSN":["2398-502X"],"issn-type":[{"value":"2398-502X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,11,7]]},"assertion":[{"value":"Indexed","URL":"https:\/\/wellcomeopenresearch.org\/articles\/7-54\/v2#article-reports","order":0,"name":"referee-status","label":"Referee status","group":{"name":"current-referee-status","label":"Current Referee Status"}},{"value":"10.21956\/wellcomeopenres.19382.r51157, Elizabeth Hamlyn, King's College Hospital NHS Foundation Trust, London, 19 Jul 2022, version 1, 1 approved, 1 approved with reservations","URL":"https:\/\/wellcomeopenresearch.org\/articles\/7-54\/v1#referee-response-51157","order":0,"name":"referee-response-51157","label":"Referee Report","group":{"name":"article-reports","label":"Article Reports"}},{"value":"10.21956\/wellcomeopenres.22528.r69785, Sherika Hanley, Department of Family Medicine, University of KwaZulu-Natal, Durban, KwaZulu-Natal, 28 Dec 2023, version 2, indexed","URL":"https:\/\/wellcomeopenresearch.org\/articles\/7-54\/v2#referee-response-69785","order":1,"name":"referee-response-69785","label":"Referee Report","group":{"name":"article-reports","label":"Article Reports"}},{"value":"The Trial is funded by the Wellcome Trust (Senior Fellowship to RAF: 206316\/Z\/17\/Z). The nested STI trial is funded by the MRC\/ESRC\/DFID\/NIHR (MR\/T040327\/1). The messaging component is funded by the Charlize Theron Africa Outreach Project (CTAOP). The menstrual management component was supported by the Swiss Development Corporation. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.","order":2,"name":"grant-information","label":"Grant Information"},{"value":"This is an open access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.","order":0,"name":"copyright-info","label":"Copyright"}]}}