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It includes 1,370 new samples contributed by MalariaGEN and VivaxGEN partner studies in addition to previously published samples from these and other sources. We provide genotype calls at over 4.5 million variable positions including over 3 million single nucleotide polymorphisms (SNPs), as well as short indels and tandem duplications. This enlarged dataset highlights major compartments of parasite population structure, with clear differentiation between Africa, Latin America, Oceania, Western Asia and different parts of Southeast Asia. Each sample has been classified for drug resistance to sulfadoxine, pyrimethamine and mefloquine based on known markers at the\n                    <ns3:italic>dhfr<\/ns3:italic>\n                    ,\n                    <ns3:italic>dhps<\/ns3:italic>\n                    and\n                    <ns3:italic>mdr1<\/ns3:italic>\n                    loci. The prevalence of all of these resistance markers was much higher in Southeast Asia and Oceania than elsewhere. This open resource of analysis-ready genome variation data from the MalariaGEN and VivaxGEN networks is driven by our collective goal to advance research into the complex biology of\n                    <ns3:italic>P. vivax<\/ns3:italic>\n                    and to accelerate genomic surveillance for malaria control and elimination.\n                  <\/ns3:p>","DOI":"10.12688\/wellcomeopenres.17795.1","type":"journal-article","created":{"date-parts":[[2022,4,14]],"date-time":"2022-04-14T08:35:09Z","timestamp":1649925309000},"page":"136","update-policy":"https:\/\/doi.org\/10.12688\/wellcomeopenres.crossmark-policy","source":"Crossref","is-referenced-by-count":53,"title":["An open dataset of Plasmodium vivax genome variation in 1,895 worldwide 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status","group":{"name":"current-referee-status","label":"Current Referee Status"}},{"value":"10.21956\/wellcomeopenres.19696.r50005, Daniel Neafsey, Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, MA, 17 May 2022, version 1, indexed","URL":"https:\/\/wellcomeopenresearch.org\/articles\/7-136\/v1#referee-response-50005","order":0,"name":"referee-response-50005","label":"Referee Report","group":{"name":"article-reports","label":"Article Reports"}},{"value":"10.21956\/wellcomeopenres.19696.r50006, Jonathan J Juliano, Division of Infectious Diseases, University of North Carolina School of Medicine, Chapel Hill, NC, 23 May 2022, version 1, indexed","URL":"https:\/\/wellcomeopenresearch.org\/articles\/7-136\/v1#referee-response-50006","order":1,"name":"referee-response-50006","label":"Referee Report","group":{"name":"article-reports","label":"Article Reports"}},{"value":"This research was funded by the Wellcome Trust (206194, 108413\/A\/15\/D, 204911); the Medical Research Council UK and the Department for International Development (DFID) (MR\/M006212\/1); and the Bill & Melinda Gates Foundation (OPP1204628, INV-001927). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.","order":2,"name":"grant-information","label":"Grant Information"},{"value":"This is an open access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.","order":0,"name":"copyright-info","label":"Copyright"}]}}