{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T05:12:55Z","timestamp":1772169175548,"version":"3.50.1"},"update-to":[{"DOI":"10.12688\/wellcomeopenres.21725.1","type":"new_version","label":"New version","source":"publisher","updated":{"date-parts":[[2024,11,8]],"date-time":"2024-11-08T00:00:00Z","timestamp":1731024000000}}],"reference-count":24,"publisher":"F1000 Research Ltd","license":[{"start":{"date-parts":[[2024,11,8]],"date-time":"2024-11-08T00:00:00Z","timestamp":1731024000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100010269","name":"Wellcome Trust","doi-asserted-by":"publisher","award":["223499\/Z\/21\/Z"],"award-info":[{"award-number":["223499\/Z\/21\/Z"]}],"id":[{"id":"10.13039\/100010269","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["wellcomeopenresearch.org"],"crossmark-restriction":false},"short-container-title":["Wellcome Open Res"],"abstract":"<ns3:p>Objective This scoping review will map the extent and type of evidence in relation to the association between maternal long term health conditions (LTCs), including multimorbidity, and child oral health. Introduction Newer theories are emerging that detail the many factors that can influence child oral health at child, family and community levels. More recently, the association between maternal general health and child oral health has been explored, with preliminary evidence suggesting a link between shared environmental factors and diet\/substance use during pregnancy causing childhood caries. Inclusion criteria All published studies that describe the relationship between maternal LTCs (including multimorbidity) and child oral health. There will be no limitation on the date of publication due to the limited number of studies available from the initial search of PubMed. The review will exclude case studies, abstracts, and grey literature. Literature must be in English language. Methods The following databases will be searched; CINAHL, Cochrane Library, Maternity and Infant Care, Medline via PubMed, Scopus, Web of Science. The search will include sources in English only and will be undertaken between April and July 2024. Studies to be included will be of any type of study design that describe a relationship between maternal long term health conditions, including maternal long term oral health conditions, and child oral health. Data extraction will be undertaken using tabulation of results by at least two independent reviewers. Narrative analysis of the evidence will be undertaken, and results will be presented in a narrative and tabular manner due to the heterogenous and limited evidence base found in the test search. This review has been registered prospectively on Open Science Framework, (https:\/\/doi.org\/10.17605\/OSF.IO\/ECSWJ). The review will also inform an Evidence Gap Map (EGM) to illustrate the current evidence base regarding maternal health factors that influence child oral health.<\/ns3:p>","DOI":"10.12688\/wellcomeopenres.21725.2","type":"journal-article","created":{"date-parts":[[2024,11,8]],"date-time":"2024-11-08T11:35:09Z","timestamp":1731065709000},"page":"299","update-policy":"https:\/\/doi.org\/10.12688\/wellcomeopenres.crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["The influence of maternal long term health conditions including multimorbidity on child oral health: A scoping review and evidence gap map protocol"],"prefix":"10.12688","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7630-2983","authenticated-orcid":false,"given":"Faith","family":"Campbell","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0457-5368","authenticated-orcid":false,"given":"Scott","family":"McGregor","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6093-4679","authenticated-orcid":false,"given":"Louise","family":"Marryat","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ryan","family":"Stewart","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jan","family":"Clarkson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9677-2886","authenticated-orcid":false,"given":"Heather","family":"Cassie","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2560","published-online":{"date-parts":[[2024,11,8]]},"reference":[{"key":"ref-1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eclinm.2023.101860","article-title":"Global and regional prevalence of multimorbidity in the adult population in community settings: a systematic review and meta-analysis.","volume":"57","author":"S Chowdhury","year":"2023","journal-title":"eClinicalMedicine."},{"key":"ref-2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.l6964","article-title":"Rising to the challenge of multimorbidity.","volume":"368","author":"C Whitty","year":"2020","journal-title":"BMJ."},{"key":"ref-3","doi-asserted-by":"publisher","DOI":"10.1186\/s12916-023-03058-4","article-title":"Maternal multimorbidity and preterm birth in Scotland: an observational record-linkage study.","volume":"21","author":"A Azcoaga-Lorenzo","year":"2023","journal-title":"BMC Med."},{"key":"ref-4","doi-asserted-by":"publisher","first-page":"650-8","DOI":"10.1177\/0022034515573272","article-title":"Global burden of untreated caries: a systematic review and metaregression.","volume":"94","author":"N Kassebaum","year":"2015","journal-title":"J Dent Res."},{"key":"ref-5","article-title":"Sugars and dental caries","year":"2017"},{"key":"ref-6","article-title":"National Dental Inspection Programme (NDIP) 2020. 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How oral health contributes to public health priorities in scotland.","volume":"2","year":"2019"},{"key":"ref-8","article-title":"Hospital tooth extractions in 0 to 19 year olds 2022.","year":"2023"},{"key":"ref-9","doi-asserted-by":"publisher","first-page":"282-6","DOI":"10.1038\/s41415-020-2056-y","article-title":"Multimorbidity: a challenge and opportunity for the dental profession.","volume":"229","author":"R Watt","year":"2020","journal-title":"Br Dent J."},{"key":"ref-10","doi-asserted-by":"publisher","first-page":"37-43","DOI":"10.1016\/S0140-6736(12)60240-2","article-title":"Epidemiology of multimorbidity and implications for health care, research, and medical education: a cross-sectional study.","volume":"380","author":"K Barnett","year":"2012","journal-title":"Lancet."},{"key":"ref-11","doi-asserted-by":"publisher","first-page":"e510-20","DOI":"10.1542\/peds.2006-3084","article-title":"Influences on children\u2019s oral health: a conceptual model.","volume":"120","author":"S Fisher-Owens","year":"2007","journal-title":"Paediatrics."},{"key":"ref-12","doi-asserted-by":"publisher","first-page":"219-27","DOI":"10.1007\/s10389-018-0936-2","article-title":"Association between maternal and child oral health and dental caries in Korea.","volume":"27","author":"S Lee","year":"2019","journal-title":"J Public Health."},{"key":"ref-13","doi-asserted-by":"publisher","first-page":"S169-74","DOI":"10.1007\/s10995-006-0095-x","article-title":"Oral health in women during preconception and pregnancy: implications for birth outcomes and infant oral health.","volume":"10","author":"K Boggess","year":"2006","journal-title":"Matern Child Health J."},{"key":"ref-14","article-title":"Follow-up to the political declaration of the third high-level meeting of the general assembly on the prevention and control of non-communicable disease.","year":"2022"},{"key":"ref-15","article-title":"Core Priorities.","year":"2023"},{"key":"ref-16","article-title":"JBI Manual for Evidence Synthesis.","author":"E Aromataris","year":"2020"},{"key":"ref-17","doi-asserted-by":"publisher","DOI":"10.1186\/s12874-018-0611-x","article-title":"Systematic review or scoping review? Guidance for authors when choosing between a systematic or scoping review approach.","volume":"18","author":"Z Munn","year":"2018","journal-title":"BMC Med Res Methodol."},{"key":"ref-18","doi-asserted-by":"publisher","first-page":"147-53","DOI":"10.1097\/XEB.0000000000000054","article-title":"Methodological guidance for systematic reviews of observational epidemiological studies reporting prevalence and cumulative incidence data.","volume":"13","author":"Z Munn","year":"2015","journal-title":"Int J Evid Based Healthc."},{"key":"ref-19","doi-asserted-by":"publisher","DOI":"10.1002\/cl2.1125","article-title":"Guidance for producing a Campbell evidence and gap map.","volume":"16","author":"H White","year":"2020","journal-title":"Campbell Syst Rev."},{"key":"ref-20","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.l4898","article-title":"RoB 2: a revised tool for assessing risk of bias in randomised trials.","volume":"366","author":"J Sterne","year":"2019","journal-title":"BMJ."},{"key":"ref-21","doi-asserted-by":"publisher","first-page":"467-73","DOI":"10.7326\/M18-0850","article-title":"PRISMA extension for Scoping Reviews (PRISMA-ScR): checklist and explanation.","volume":"169","author":"A Tricco","year":"2018","journal-title":"Ann Intern Med."},{"key":"ref-22","doi-asserted-by":"publisher","first-page":"e587-e597","DOI":"10.1016\/S2468-2667(21)00107-9","article-title":"Examining variation in the measurement of multimorbidity in research: a systematic review of 566 studies.","volume":"6","author":"I Ho","year":"2021","journal-title":"Lancet Public Health."},{"key":"ref-23","article-title":"Global oral health status report: towards universal health coverage for oral health by 2030: executive summary","year":"2023"},{"key":"ref-24","doi-asserted-by":"publisher","first-page":"56-64","DOI":"10.1016\/j.jclinepi.2013.08.005","article-title":"Applying an equity lens to interventions: using PROGRESS ensures consideration of socially stratifying factors to illuminate inequities in health.","volume":"67","author":"J O'Neill","year":"2014","journal-title":"J Clin Epidemiol."}],"container-title":["Wellcome Open Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/wellcomeopenresearch.org\/articles\/9-299\/v2\/xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/wellcomeopenresearch.org\/articles\/9-299\/v2\/pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/wellcomeopenresearch.org\/articles\/9-299\/v2\/iparadigms","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,15]],"date-time":"2024-11-15T01:50:12Z","timestamp":1731635412000},"score":1,"resource":{"primary":{"URL":"https:\/\/wellcomeopenresearch.org\/articles\/9-299\/v2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11,8]]},"references-count":24,"URL":"https:\/\/doi.org\/10.12688\/wellcomeopenres.21725.2","relation":{"has-version":[{"id-type":"doi","id":"10.12688\/wellcomeopenres.21725.1","asserted-by":"subject"}],"has-review":[{"id-type":"doi","id":"10.21956\/wellcomeopenres.25787.r110889","asserted-by":"subject"},{"id-type":"doi","id":"10.21956\/wellcomeopenres.25787.r110889","asserted-by":"object"},{"id-type":"doi","id":"10.21956\/wellcomeopenres.25787.r110702","asserted-by":"object"}]},"ISSN":["2398-502X"],"issn-type":[{"value":"2398-502X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,11,8]]},"assertion":[{"value":"Indexed","URL":"https:\/\/wellcomeopenresearch.org\/articles\/9-299\/v2#article-reports","order":0,"name":"referee-status","label":"Referee status","group":{"name":"current-referee-status","label":"Current Referee Status"}},{"value":"10.21956\/wellcomeopenres.23999.r86723, Betsy Foxman, University of Michigan,, Ann Arbor, 15 Jul 2024, version 1, 1 approved, 1 approved with reservations, 1 not approved","URL":"https:\/\/wellcomeopenresearch.org\/articles\/9-299\/v1#referee-response-86723","order":0,"name":"referee-response-86723","label":"Referee Report","group":{"name":"article-reports","label":"Article Reports"}},{"value":"<b>Faith Campbell<\/b>; \n<i>Posted: 06 Nov 2024<\/i>; 1) There is no definition or inclusion criteria regarding child oral health (this is a fatal flaw). \n<b>Response:&nbsp; <\/b>Thank you for highlighting this. This has been addressed by adding the following paragraph to the background (page 2 paragraph 7) \u2018\n<i>Dental caries will be the primary outcome focus of this scoping review. This is because the work which this review will inform will focus on data on child dental caries in Scotland. Consideration will also be given to conditions of enamel that increase tooth susceptibility to enamel such as molar incisor hypomineralisation (MIH) and developmental defects of enamel (DDE) as they may be causative pathways in any link between maternal health conditions and childhood caries. Thereafter, in this review \u2018oral health will be defined as dental caries, MIH and DDE. Other oral conditions in children will not be considered due to an absence of theoretical links between them and maternal health conditions.\u2019 <\/i> The inclusion and exclusion criteria have been refined to reflect this (page 5 paragraph 4) \u2018\n<i>Condition<\/i> \n<i>Inclusion criteria: <\/i>  \n<i>Exposure: single or multiple health conditions (multimorbidity) affecting mothers at any time from prior to conception to the child being 16 years old.<\/i>  \n<i>Outcome: Child oral health defined as dental caries, MIH and DDE Exclusion: <\/i>  \n<i>Exposure: No clear definition of health condition that is affecting mother&nbsp; <\/i>  \n<i>Outcome:&nbsp; Dental trauma, malocclusion and gingivitis\u2019<\/i>  2) Lack of details on the types of maternal oral health and other morbidities that will be included as multimorbidities. It is likely there will be sufficient literature on gum disease and dental caries but little on injury or factors such as tongue rings. Similarly, the literature on oral health and diabetes and heart disease is robust but limited on factors such as sexually transmitted bacterial or viral infections in the oral cavity. &nbsp; \n<b>Response:&nbsp;<\/b>Thank you for your comment. For clarity this review will not be exploring multimorbidity due to the paucity in evidence revealed by the pilot search for this review. We hope that this is clarified by the rephrasing of the following paragraph (page 4 paragraph 3) \u2018The objective of this scoping review is to map existing literature on the relationship between maternal long-term health conditions, and child oral health. Maternal long term health conditions have been chosen because an initial pilot search found such limited evidence regarding maternal multimorbidity as a concept, that a broader search to map the evidence base on maternal long term health conditions and child oral health would provide greater value. This will subsequently inform research regarding the presence of multiple long term health conditions (multimorbidity) and child oral health.\u2019 We have decided to exclude behaviour and lifestyle choices as this is much more challenging to explore, so within a field which is sparsely researched thus far, we felt it more important to explore health conditions. Furthermore these health conditions are examinable in the datasets which we will use in later stages of this project, unlike factors such as nose ring wearing. We agree that bacterial transmission from mother to child should be considered. As this wider programme of work focusses on multiple long term conditions (multimorbidity), only long terms conditions will be explored. We are aware of the significant body of research on bacteria in mothers\u2019 oral cavity and the impact of transmission of this to children with a theory of caries transmission, such as strep mutans. Given that it is widely accepted within the scientific community that caries is caused by dysbiosis in the oral cavity rather than transmission of a specific commensal, we made the decision to exclude bacterial transmission from mother to child in this review. Multiple papers discussing this were found in the initial search and therefore this will be discussed in greater detail in the discussion of results. &nbsp;  3) The background mentions the importance of shared environmental factors and social inequalities, but these factors are not identified in the research questions nor in the data collected. &nbsp;Taking those factors into account will be particularly important for cross-cultural comparisons. \n<b>Response:&nbsp;<\/b>We agree that shared environmental factors and social inequalities are both important when considering dental caries in children and multiple long-term conditions in mothers. We have not included them in this review as the evidence is so indisputable on this that we felt it was most important to focus on what is not known with such certainty regarding causes of caries in children (1, 2). However, deprivation and social inequalities will be key confounders in our future research exploring mothers\u2019 health data and childhood caries.","URL":"https:\/\/wellcomeopenresearch.org\/articles\/9-299\/v2#referee-comment-5892","order":1,"name":"referee-comment-5892","label":"Referee Comment","group":{"name":"article-reports","label":"Article Reports"}},{"value":"10.21956\/wellcomeopenres.23999.r98125, Amit Vasant Mahuli, Department of Public Health Dentistry, Rajendra Institute of Medical Sciences, Ranchi, Jharkhand, 23 Sep 2024, version 1, 1 approved, 1 approved with reservations, 1 not approved","URL":"https:\/\/wellcomeopenresearch.org\/articles\/9-299\/v1#referee-response-98125","order":2,"name":"referee-response-98125","label":"Referee Report","group":{"name":"article-reports","label":"Article Reports"}},{"value":"<b>Faith Campbell<\/b>; \n<i>Posted: 06 Nov 2024<\/i>; The study protocol, influence of maternal health factors, including multimorbidity on child oral health, is a promising topic to explore the maternal factors and their indirect and direct influences on the oral health of the child. \n<b>Response:&nbsp;<\/b>Thank you for your feedback, we are pleased that you agree on the importance of this topic.  The rationale of the study can be more clearly stated as the maternal multi-morbidity is vague as per the definition, and the use of term child oral health is also a high age range that can lead to heterogenicity of the data extracted. As different age groups will have different oral health needs and oral health issues.&nbsp; \n<b>Response:&nbsp;<\/b>There are challenges when studying multimorbidity due to heterogenous definitions across literature which is why \u2018health conditions\u2019 were selection for this review. &nbsp; Thank you, we have clarified that in this review child will mean an individual below the age of 18 per the United Nations and Scottish Government definitions on page 2 paragraph 6. &nbsp; If evidence can be explored by age group this will be discussed within the paper (page 2 paragraph 6)  The studies included in the scoping review and their quality assessment, if done, will be challenging as many study designs will be included. \n<b>Response:&nbsp;<\/b>We agree that such a heterogenous evidence base may be more challenging to appraise however since the pilot search revealed such limited studies for inclusion, it was decided to include all available evidence to provide as much evidence as possible.  The data showing severe periodontal disease could be challenging as their are more reported cases of gingival disease than severe periodontal disease in children.&nbsp; \n<b>Response:&nbsp;<\/b>We also agree that being such a rare outcome, severe periodontal disease will be scarce. Periodontal disease and gingival conditions in children will not be included as an outcome in this review.  The protocol fits in to the scoping review category, but the rationale, condition, and assessment are going to be challenging as the data obtained will be difficult to fit in the data charting tool. \n<b>Response:&nbsp;<\/b>We agree that the data obtained will require amendments to the traditional data charting tools used for scoping review and considered this when developing our protocol. We have therefore amended the charting tool to reflect this and will iteratively develop this to best extract data from the studies that are included, per JBI protocol for scoping reviews (page 11).","URL":"https:\/\/wellcomeopenresearch.org\/articles\/9-299\/v2#referee-comment-5893","order":3,"name":"referee-comment-5893","label":"Referee Comment","group":{"name":"article-reports","label":"Article Reports"}},{"value":"10.21956\/wellcomeopenres.23999.r98124, Ratna Indriyanti, Department of Pediatric Dentistry, Faculty of Dentistry, Universitas Padjadjaran, Indonesia, 09 Oct 2024, version 1, 1 approved, 1 approved with reservations, 1 not approved","URL":"https:\/\/wellcomeopenresearch.org\/articles\/9-299\/v1#referee-response-98124","order":4,"name":"referee-response-98124","label":"Referee Report","group":{"name":"article-reports","label":"Article Reports"}},{"value":"<b>Faith Campbell<\/b>; \n<i>Posted: 06 Nov 2024<\/i>; 1. The title listed does not adequately describe the splendor and depth of the research carried out. \n<b>Response: <\/b>Thank you, the title has been updated to \u2018The Influence of Maternal Health Factors Long Term Health Conditions Including Multimorbidity on Child Oral Health: A Scoping Review and Evidence Gap Map Protocol\u2019, to better reflect the scope of this review (page 1)  2. Provide a more detail explanation regarding health condition in the oral cavity other than caries. \n<b>Response:&nbsp;<\/b>Thank you, we agree that oral health conditions could have been better detailed and hope that the addition of the following paragraph satisfies this (page 3 paragraph 1) \u2018Dental caries will be the primary outcome focus of this scoping review. This is because the work which this review will inform will focus on data on child dental caries in Scotland. Consideration will also be given to conditions of enamel that increase tooth susceptibility to enamel such as molar incisor hypomineralisation (MIH) and developmental defects of enamel (DDE) as they may be causative pathways in any link between maternal health conditions and childhood caries. Thereafter, in this review \u2018oral health will be defined as dental caries, MIH and DDE. Other oral conditions in children will not be considered due to an absence of theoretical links between them and maternal health conditions. \u2018  3, The alleged relationship between multimorbidity and childrens oral health has not been clearly described. \n<b>Response:&nbsp;<\/b>Due to this being a novel review, there is no evidence that describes a relationship between multimorbidity and child oral health. This gap in knowledge forms the need for the review. We have described current theories on possible links in the following paragraphs &nbsp; (Page 3 paragraphs 2 and 3) \u2018\n<b>Possible link\u2019<\/b> There has been a demonstrated link between poor oral health, socio-economic inequalities and co-morbidities including diabetes, cardiovascular disease, rheumatoid arthritis, chronic obstructive pulmonary disease (COPD), pneumonia in the elderly, anxiety and depressive disorders, and increased risk of developing cognitive impairment and dementia (3). This link is frequently bi-directional. However, the link between multimorbidity and oral health, particularly dental caries, is less researched (3).&nbsp; Multimorbidity and poor oral health share some common risk factors such as deprivation: both dental caries and multimorbidity disproportionately affect those living in more deprived areas (4, 5). The increasing number of people living with multimorbidity, results in an increasing need for new models of dental care to address multimorbidity in relation to adult oral health (3). Individuals with multimorbidity have a greater treatment burden than the general population, whereby they need to access treatment from multiple (often uncoordinated) healthcare professionals (3). These care plans are often complex and those with multimorbidity are often taking multiple medications (3). Best care for these patients requires appropriate training of oral health professionals, changes to the practice and delivery of oral health care and a focus of research on multimorbidity and oral health (3). \n<b>(Page 3 paragraph 4)<\/b> \n<b>Current Evidence<\/b> Initial explorations indicate that there is a limited but evolving body of evidence regarding child oral health and child or maternal long term health conditions. Newer theoretical models are emerging that detail the many factors that can influence child oral health at child, family and community levels (6). The association between maternal long term health conditions and child oral health has been explored, with preliminary evidence suggesting a link between shared environmental factors and direct maternal-to-child transfer of bacteria, diet and substance use during pregnancy causing childhood caries (7, 8). Maternal long term health conditions may additionally create challenges in supporting child oral care and in attending dental appointments (6). To date, no review has synthesised this evidence to examine the relationship between maternal long term health conditions and child oral health.","URL":"https:\/\/wellcomeopenresearch.org\/articles\/9-299\/v2#referee-comment-5894","order":5,"name":"referee-comment-5894","label":"Referee Comment","group":{"name":"article-reports","label":"Article Reports"}},{"value":"10.21956\/wellcomeopenres.25787.r110889, Anwar Merchant, University of South Carolina, Columbia, 15 Nov 2024, version 2, indexed","URL":"https:\/\/wellcomeopenresearch.org\/articles\/9-299\/v2#referee-response-110889","order":6,"name":"referee-response-110889","label":"Referee Report","group":{"name":"article-reports","label":"Article Reports"}},{"value":"FC is a fellow on the Multimorbidity Doctoral Training Programme for Health Professionals, which is supported by the Wellcome Trust (223499\/Z\/21\/Z) and is advised and supervised by HC, JC, CM, LM, RS, TW and LY). This work has been funded by this Wellcome Trust grant. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.","order":7,"name":"grant-information","label":"Grant Information"},{"value":"This is an open access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.","order":0,"name":"copyright-info","label":"Copyright"}]}}