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The differentiation of endocrine hypertension provides an opportunity to cure and prevent target organ damage. PA is the most common cause of secondary hypertension, which significantly increases the risk of cardiovascular disease compared to essential hypertension; thus, patients with clinical manifestations suggestive of secondary hypertension should be screened for PA. PPGL are rare but can be fatal when misdiagnosed. PPGL are the most common hereditary endocrine tumors; therefore, genetic testing using next-generation sequencing panels is recommended. Herein, we aimed to summarize the characteristic clinical symptoms of PA and PPGL and when and how diagnostic tests and treatment strategies should be performed.<\/jats:p>","DOI":"10.12701\/jyms.2024.00752","type":"journal-article","created":{"date-parts":[[2024,9,19]],"date-time":"2024-09-19T08:16:17Z","timestamp":1726733777000},"page":"269-278","update-policy":"https:\/\/doi.org\/10.12701\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Screening and treatment of endocrine hypertension focusing on adrenal gland disorders: a narrative review"],"prefix":"10.12701","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3336-7557","authenticated-orcid":true,"given":"Seung Min","family":"Chung","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"4953","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1186\/s40885-023-00243-8"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1210\/er.2017-00054"},{"key":"ref3","volume-title":"","author":"Kotchen","year":"2022"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/eht534"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1111\/joim.12831"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2017.01.052"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2003-031337"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1097\/hjh.0000000000001088"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1136\/bmj-2021-065250"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1210\/er.2018-00139"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016\/s2213-8587(17)30319-4"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1161\/hypertensionaha.119.14063"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.3803\/enm.2023.1789"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1097\/hjh.0000000000002510"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2015-4061"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehac432"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1186\/s40885-023-00234-9"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1038\/jhh.2011.47"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2005.01.015"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1097\/hjh.0000000000002250"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1097\/00004872-199512010-00054"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2016-3206"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1097\/hjh.0000000000002216"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1038\/s41371-023-00875-1"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2018-01394"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.3803\/enm.2022.1535"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1210\/clinem\/dgz150"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.1161\/hypertensionaha.123.21563"},{"key":"ref29","doi-asserted-by":"publisher","DOI":"10.1161\/hypertensionaha.111.175083"},{"key":"ref30","doi-asserted-by":"publisher","DOI":"10.1161\/hypertensionaha.123.22281"},{"key":"ref31","doi-asserted-by":"publisher","DOI":"10.1016\/s0748-7983(03)00051-9"},{"key":"ref32","doi-asserted-by":"publisher","DOI":"10.1161\/hypertensionaha.113.01316"},{"key":"ref33","doi-asserted-by":"publisher","DOI":"10.1530\/eje-12-0631"},{"key":"ref34","doi-asserted-by":"publisher","DOI":"10.1016\/s2213-8587(17)30135-3"},{"key":"ref35","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-131-2-199907200-00005"},{"key":"ref36","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-med-042921-100438"},{"key":"ref37","doi-asserted-by":"publisher","DOI":"10.1097\/meg.0000000000001678"},{"key":"ref38","doi-asserted-by":"publisher","DOI":"10.1056\/nejm199909023411001"},{"key":"ref39","doi-asserted-by":"publisher","DOI":"10.1016\/0022-4731(89)90169-6"},{"key":"ref40","doi-asserted-by":"publisher","DOI":"10.1097\/fjc.0000000000000091"},{"key":"ref41","doi-asserted-by":"publisher","DOI":"10.1097\/mnh.0000000000000340"},{"key":"ref42","volume-title":"Efficacy and safety of finerenone in patients with primary aldosteronism. 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