{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,3,31]],"date-time":"2025-03-31T00:34:13Z","timestamp":1743381253705},"reference-count":36,"publisher":"Medical Association of Nippon Medical School","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Nippon Med Sch"],"published-print":{"date-parts":[[2001]]},"DOI":"10.1272\/jnms.68.154","type":"journal-article","created":{"date-parts":[[2002,8,26]],"date-time":"2002-08-26T17:34:57Z","timestamp":1030383297000},"page":"154-164","source":"Crossref","is-referenced-by-count":3,"title":["The Protective Effect of Hepatocyte Growth-Promoting Factor (pHGF) Against Carbon Tetrachloride-Induced Acute Liver Injury in Rats"],"prefix":"10.1272","volume":"68","author":[{"given":"Wei","family":"Dai","sequence":"first","affiliation":[{"name":"Department of Pathology, Nippon Medical School"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shigeru","family":"Sato","sequence":"additional","affiliation":[{"name":"Central Institute for Electron Microscopic Researches, Nippon Medical School"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Goro","family":"Asano","sequence":"additional","affiliation":[{"name":"Department of Pathology, Nippon Medical School"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"21","reference":[{"key":"1","unstructured":"1) Zhang Y, Chen G, Kong X, Zheng G, Yang F, Hu J: Purification and application of pHGF in liver disease patients. J Clini Hepatol 1991; 7: 15-19."},{"key":"2","unstructured":"2) Zhang Y, Kong X, Zheng G, Chen G, Yang E: Evaluation of hepatocyte growth-promoting factors in treating 1687 cases of fulminate hepatitis. (brief report) Chinese Med J 1995; 108: 928-929."},{"key":"3","unstructured":"3) Kong X, Zhang Y, Zhou Q, Zhen G, Yang L, Zhang C, Xiao X: Establishment of monoclonal antibody against promoting hepatocyte growth factor and their immunohistochemical studies. Chinese Journal of Pathophysiology 1994; 10: 165-168."},{"key":"4","doi-asserted-by":"crossref","unstructured":"4) Nakamura T, Nawa K, Ichihara A: Partial purification and characterization of hepatocyte growth fator from serum of hepatectomized rats. Biochem Biophys Res Commun 1984; 122: 1450-1459.","DOI":"10.1016\/0006-291X(84)91253-1"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5) Russell WE, McGowan JA, Bucher NLR: Partial characterization of hepatocyte growth fator from rat platelets. J Cell Physiol 1984; 119: 183-192.","DOI":"10.1002\/jcp.1041190207"},{"key":"6","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1038\/342440a0","volume":"342","year":"1989","unstructured":"6) Nakamura T, Nishizawa T, Hagiya M, Seki T, Shimonishi M, Sugimura A, Tashiro, Shimizu S: Molecular cloning and expression of human hepatocyte growth factor. Nature 1989; 342: 440-443.","journal-title":"?Nature","ISSN":"http:\/\/id.crossref.org\/issn\/0028-0836","issn-type":"print"},{"key":"7","doi-asserted-by":"crossref","unstructured":"7) Miyazawa K, Tsubouchi H, Naka D, Takahashi K, Okigaki M, Gohda E, Daikuhara Y, Kitamura M: Molecular cloning and sequence analysis of cDNA for human hepatocyte growth fator. Biochem Biophys Res Commun 1989; 163: 967-973.","DOI":"10.1016\/0006-291X(89)92316-4"},{"key":"8","unstructured":"8) Matsumoto K, Nakamura T: Hepatocyte growth fator: molecular structure, roles in liver regeneration, and other biological functions. Crit Rev Oncol 1992; 3: 27-54."},{"key":"9","doi-asserted-by":"crossref","unstructured":"9) Sato S, Dai w, Liu X, Asano G: The protective effect of hepatocyte growth-promoting factor (pHGF) against carbon tetrachloride-induced acute liver injury in rats: an ultrastructural study. Med Electron Microsc 1999; 32: 184-192.","DOI":"10.1007\/s007950050026"},{"key":"10","doi-asserted-by":"publisher","unstructured":"10) Okano J, Shiota G, Kawasaki H: Protective action of hepatocyte growth factor for acute liver injury caused by D-galactosamine in transgenic mice. Hepatology 1997; 26: 1241-1249.","DOI":"10.1053\/jhep.1997.v26.pm0009362368"},{"key":"11","doi-asserted-by":"publisher","unstructured":"11) Yasuda H, Imai E, Shiota A, Fujise N, Morinaga T, Higashio K: Antifibrogenic effect of a deletion variant of hepatocyte growth factor on liver fibrosis in rats. Hepatology 1996; 24: 636-643.","DOI":"10.1053\/jhep.1996.v24.pm0008781336"},{"key":"12","doi-asserted-by":"publisher","unstructured":"12) Schirmacher P, Geerts A, Pietrangelo A, Dienes HP, Rogler CH: Hepatocyte growth factor\/hepatopoietin A is expressed in fat storing cells from rat liver but not myofibroblast-like cells derived from fat storing cells. Hepatology 1992; 15: 5-11.","DOI":"10.1002\/hep.1840150103"},{"key":"13","first-page":"1585","volume":"21","year":"1995","unstructured":"13) Morita M, Watanabe Y, Akaike T: Protective effect of hepatocyte growth factor on interferon-gamma-induced cytoxicity in mouse hepatocytes. Hepatology 1995; 21: 1585-1593.","journal-title":"Hepatology","ISSN":"http:\/\/id.crossref.org\/issn\/0270-9139","issn-type":"print"},{"key":"14","unstructured":"14) Lu L, Wang F, Jia Y, Pan Y, Li J, Yu Y, Zhang Y: The influence of pre-treatment with pHGF on the Fas antigen expressions in mouse hepatocyte damages induced by Con-A. J Shang Hai Immu 1998; 18: 332-333."},{"key":"15","doi-asserted-by":"crossref","unstructured":"15) Nakamura T, Teramoto H, Ichihara A: Purification and characterization of a growth factor from rat platelets for mature parenchymal hepatocytes in primary cultures. Proc Natl Acad Sci USA 1986; 83: 6489-6493.","DOI":"10.1073\/pnas.83.17.6489"},{"key":"16","doi-asserted-by":"publisher","unstructured":"16) LaBrecque D R, Steele G, Fogerty S, Wilson M, Barton J: Purification and physiol-chemical characterization of hepatic stimulator. Hepatology 1987; 7: 100-106.","DOI":"10.1002\/hep.1840070121"},{"key":"17","doi-asserted-by":"crossref","unstructured":"17) Miyazawa K, Shimomura T, Kitamura A, Kondo J, Morimoto Y, Kitamura N: Molecular cloning and sequence analysis of the cDNA for a human serine protease responsible for activation of hepatocyte growth factor. Structural similarity of the protease precursor to blood coagulation factor XII. J Biol Chem 1993; 268: 10024-10028.","DOI":"10.1016\/S0021-9258(18)82167-6"},{"key":"18","doi-asserted-by":"crossref","unstructured":"18) Rao K, Recknagel RO: Early onset of lipoperoxidation in rat liver after CCl4 administration. Expl Mol Pathol 1968; 9: 271-278.","DOI":"10.1016\/0014-4800(68)90041-5"},{"key":"19","doi-asserted-by":"crossref","unstructured":"19) Reynolds ES: Liver parenchymal cell injury. I. Initial alterations of the cell following poisoning with carbon tetrachloride. J Cell Biol 1963; 19: 139-156.","DOI":"10.1083\/jcb.19.1.139"},{"key":"20","unstructured":"20) Villarruel MC, Castro JA: Irreversible binding of carbon tetrachloride to microsomal phospholipids. Free radical nature of the reactive specie and alterations in the physio-chemical properties of the target fatty acids. Res Comm Chem Pathol and Pharm 1975; 10: 105-116."},{"key":"21","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3109\/00498257309151495","volume":"3","year":"1973","unstructured":"21) Uehleke H, Hellmer KH, Tabarelli S: Binding of 14C-carbon tetrachloride to microsomal proteins in vitro and formation of CHCl3 by reduced liver microsomes. Xenobiotica 1973; 3: 1-11.","journal-title":"Xenobiotica","ISSN":"http:\/\/id.crossref.org\/issn\/0049-8254","issn-type":"print"},{"key":"22","doi-asserted-by":"crossref","unstructured":"22) Slater TF: Free-radical mechanisms in tissue injury (Review article). Biochem J 1984; 222: 1-15.","DOI":"10.1042\/bj2220001"},{"key":"23","doi-asserted-by":"crossref","unstructured":"23) Ansari GAS, Mollen M T, Reynolds: Evidence for in vivo covalent binding of CCl3&middot; Derived from CCl4 to cholesterol of rat liver. Biochem Phar 1982; 31: 3509-3510.","DOI":"10.1016\/0006-2952(82)90634-7"},{"key":"24","doi-asserted-by":"crossref","unstructured":"24) Recknagel RO, Glende EA Jr, Dolak JA, Waller RL: Mechanism of carbon tetrachloride toxicity. Pharmac Ther 1989; 43: 139-154.","DOI":"10.1016\/0163-7258(89)90050-8"},{"key":"25","doi-asserted-by":"crossref","unstructured":"25) Mansuy D, Beaune P, Crestell T, Lange M, Leroux J-P: Evidence for phosgene formation during liver microsomal oxidation of chloroform. Biochem Biophys Res Commum 1977; 79: 513-517.","DOI":"10.1016\/0006-291X(77)90187-5"},{"key":"26","doi-asserted-by":"crossref","unstructured":"26) Reynolds ES, Thiers RE, Vallee BL: Mitochondrial function and metal content in carbon tetrachloride poisoning. J Bion Chem 1962; 237: 3546-3551.","DOI":"10.1016\/S0021-9258(19)70854-0"},{"key":"27","doi-asserted-by":"publisher","unstructured":"27) Honma T, Suda M: Changes in plasma lipoproteins as toxicity markers for carbon tetrachloride, chloroform, and dichloromethane. Industrial Health 1997; 35: 519-531.","DOI":"10.2486\/indhealth.35.519"},{"key":"28","doi-asserted-by":"publisher","unstructured":"28) Takayama F, Egashira T, Kudo Y, Yamanaka Y: Effects of anti-free radical interventions on phosphatidylcholine hydroperoxide in plasma after ischemia-reperfusion in the liver of rats. Biochemical Pharmacology 1993; 46: 1749-1757.","DOI":"10.1016\/0006-2952(93)90579-L"},{"key":"29","doi-asserted-by":"crossref","unstructured":"29) Egashira T, Nagai T, Kimba Y, Murayama F, Goto S, Kudo y, Sudo S, Kono T, Yamanaka y: An injury of the liver caused by ischemia-reperfusion in rat liver. Folia Pharmacol Japan (Eng Abstr) 1991; 97: 339-350.","DOI":"10.1254\/fpj.97.6_339"},{"key":"30","first-page":"129","volume":"2","year":"1981","unstructured":"30) Adachi Y, Horii K, Suwa M, Tanihata M, Ohba Y, Yamamoto T: Serum glutathione stransferase in experimental liver damage in rats. Gastroenterologia Japonica 1981; 2: 129-133.","journal-title":"Gastroenterologia Japonica","ISSN":"http:\/\/id.crossref.org\/issn\/0435-1339","issn-type":"print"},{"key":"31","first-page":"22","volume":"53","year":"1999","unstructured":"31) Nakanishi Y, Okuda T, Abe H: Effects of geraniin on the liver in rats III-correlation between lipid accumulations and liver damage in CCl<SUB>4<\/SUB>-treated rats. Natural Medicines 1999; 53: 22-26.","journal-title":"Journal of Natural Medicines","ISSN":"http:\/\/id.crossref.org\/issn\/1340-3443","issn-type":"print"},{"key":"32","unstructured":"32) Recknagel R, Litteria M: Biochemical changes in carbon tetrachloride fatty liver. Am J Path 1960; 36: 521-531."},{"key":"33","doi-asserted-by":"crossref","unstructured":"33) Recknagel R, Lombardi B: Studies of biochemical changes in subcellular particles of rat liver and their relationship to a new hypothesis regarding the pathogenesis of carbon tetrachloride fat accumulation. J Biol Chem 1961; 236: 564-569.","DOI":"10.1016\/S0021-9258(18)64404-7"},{"key":"34","doi-asserted-by":"crossref","unstructured":"34) Chauveau J, Moule Y, Rouiller C, Scheebeli J: Isolation of smooth vesicles and free ribosomes from rat liver microsomes. J Cell Biol 1962; 12: 17-29.","DOI":"10.1083\/jcb.12.1.17"},{"key":"35","doi-asserted-by":"crossref","unstructured":"35) Edward A, Smuckler M, Oscar A, Iseri N, Earl P, Benditl M: An intracellular defect in protein synthesis induced by carbon tetrachloride. J Exp Med 1962; 116: 55-71.","DOI":"10.1084\/jem.116.1.55"},{"key":"36","unstructured":"37) Reid I, Shinozuka H, Sidransky H: Polyribosomal disaggregation induced by puromycin and its reversal with time: An ultrastructural study of mouse liver. Lab Invest 1970; 23: 119-129."}],"container-title":["Journal of Nippon Medical School"],"original-title":["\u56db\u5869\u5316\u70ad\u7d20\u6295\u4e0e\u306b\u3088\u308b\u30e9\u30c3\u30c8\u306e\u6025\u6027\u809d\u969c\u5bb3\u306b\u5bfe\u3059\u308b\u4fc3\u809d\u7d30\u80de\u5897\u6b96\u56e0\u5b50 (pHGF) \u306e\u6cbb\u7642\u52b9\u679c"],"language":"en","link":[{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/jnms\/68\/2\/68_2_154\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,5,27]],"date-time":"2021-05-27T05:51:35Z","timestamp":1622094695000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/jnms\/68\/2\/68_2_154\/_article\/-char\/ja\/"}},"subtitle":["II. Protective Effects on Cell Membrane Injury"],"short-title":[],"issued":{"date-parts":[[2001]]},"references-count":36,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2001]]}},"URL":"https:\/\/doi.org\/10.1272\/jnms.68.154","relation":{},"ISSN":["1345-4676","1347-3409"],"issn-type":[{"value":"1345-4676","type":"print"},{"value":"1347-3409","type":"electronic"}],"subject":[],"published":{"date-parts":[[2001]]}}}