{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T21:09:58Z","timestamp":1792098598681,"version":"4.4.0"},"reference-count":20,"publisher":"Medical Association of Nippon Medical School","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Nippon Med Sch"],"published-print":{"date-parts":[[2017]]},"DOI":"10.1272\/jnms.84.193","type":"journal-article","created":{"date-parts":[[2017,10,4]],"date-time":"2017-10-04T22:32:25Z","timestamp":1507156345000},"page":"193-197","source":"Crossref","is-referenced-by-count":10,"title":["Aortic Valve Replacement for the Management of Heyde Syndrome: A Case Report"],"prefix":"10.1272","volume":"84","author":[{"given":"Akihiko","family":"Shibamoto","sequence":"first","affiliation":[{"name":"Third Department of Internal Medicine, Nara Medical University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hideto","family":"Kawaratani","sequence":"additional","affiliation":[{"name":"Third Department of Internal Medicine, Nara Medical University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takuya","family":"Kubo","sequence":"additional","affiliation":[{"name":"Third Department of Internal Medicine, Nara Medical University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Norihisa","family":"Nishimura","sequence":"additional","affiliation":[{"name":"Third Department of Internal Medicine, Nara Medical University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shinya","family":"Sato","sequence":"additional","affiliation":[{"name":"Third Department of Internal Medicine, Nara Medical University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenichiro","family":"Seki","sequence":"additional","affiliation":[{"name":"Third Department of Internal Medicine, Nara Medical University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasuhiko","family":"Sawada","sequence":"additional","affiliation":[{"name":"Third Department of Internal Medicine, Nara Medical University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroaki","family":"Takaya","sequence":"additional","affiliation":[{"name":"Third Department of Internal Medicine, Nara Medical University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasushi","family":"Okura","sequence":"additional","affiliation":[{"name":"Third Department of Internal Medicine, Nara Medical University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kousuke","family":"Takeda","sequence":"additional","affiliation":[{"name":"Third Department of Internal Medicine, Nara Medical University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masakazu","family":"Uejima","sequence":"additional","affiliation":[{"name":"Third Department of Internal Medicine, Nara Medical University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tadashi","family":"Namisaki","sequence":"additional","affiliation":[{"name":"Third Department of Internal Medicine, Nara Medical University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kei","family":"Moriya","sequence":"additional","affiliation":[{"name":"Third Department of Internal Medicine, Nara Medical University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akira","family":"Mitoro","sequence":"additional","affiliation":[{"name":"Third Department of Internal Medicine, Nara Medical University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junichi","family":"Yamao","sequence":"additional","affiliation":[{"name":"Department of Endoscopy, Nara Medical University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hitoshi","family":"Yoshiji","sequence":"additional","affiliation":[{"name":"Third Department of Internal Medicine, Nara Medical University"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"21","reference":[{"key":"1","unstructured":"1. Massyn M, Khan SA: Heyde syndrome: a common diagnosis in older patients with severe aortic stenosis. Age Ageing 2009; 38: 267-270."},{"key":"2","doi-asserted-by":"crossref","unstructured":"2. Loscalzo J: From Clinical Observation to Mechanism-Heyde's Syndrome. N Engl J Med 2012; 367: 1954-1956.","DOI":"10.1056\/NEJMcibr1205363"},{"key":"3","doi-asserted-by":"crossref","unstructured":"3. Heyde EC: Gastrointestinal bleeding in aortic stenosis (Letter). N Engl J Med 1958; 259: 196.","DOI":"10.1056\/NEJM195807242590416"},{"key":"4","unstructured":"4. Pate GE, Chandavimol M, Naiman SC, Webb JG: Heyde's Syndrome: A review. J Heart Valve Dis 2004; 13: 701-712."},{"key":"5","doi-asserted-by":"crossref","unstructured":"5. Ogano M, Iwasaki Y, Takano H: Successful Colectomy for the Treatment of Repetitive Bleeding from Colonic Angiodysplasia in a Patient with Heyde Syndrome. Intern Med 2006; 45: 355-358.","DOI":"10.2169\/internalmedicine.45.1526"},{"key":"6","doi-asserted-by":"crossref","unstructured":"6. Gandhi V, Philip S, Nagral S: Heyde Syndrome. Trop Gastroenterol 2010; 31: 120-121.","DOI":"10.4103\/TROG_20103102_120"},{"key":"7","doi-asserted-by":"crossref","unstructured":"7. Saad RA, Lwaleed BA, Kazmi RS: Gastrointestinal Bleeding and Aortic Stenosis (Heyde Syndrome): The Role of Aortic Valve Replacement. J Card Surg 2013; 28: 414-416.","DOI":"10.1111\/jocs.12131"},{"key":"8","doi-asserted-by":"crossref","unstructured":"8. Morishima A, Marui A, Shimamoto T, Saji Y, Tambara K, Nishina T, Komeda M: Successful Aortic Valve Replacement for Heyde Syndrome With Confirmed Hematologic Recovery. Ann Thorac Surg 2007; 83: 287-288.","DOI":"10.1016\/j.athoracsur.2006.05.082"},{"key":"9","unstructured":"9. G\u00fcl M, S\u00fcrgit O, \u00d6zal E, \u00d6rmeci A, Bakir I: Treatment of aortic valve stenosis and gastrointestinal bleeding by transcatheter aortic valve implantation in Heyde syndrome. Anadolu Kardiyol Derg 2012; 12: 689-696."},{"key":"10","doi-asserted-by":"crossref","unstructured":"10. Dos Santos VM, Dos Santos LA, Modesto AA, Amui MO: Heyde syndrome in a 71-year-old man who underwent chest radiotherapy at young age. An Sist Sanit Navar 2013; 36: 339-345.","DOI":"10.4321\/S1137-66272013000200020"},{"key":"11","unstructured":"11. Maor NR: Heyde Syndrome: Resolution of Anemia after Aortic Valve Surgery. IMAJ 2013; 15: 455-457."},{"key":"12","doi-asserted-by":"crossref","unstructured":"12. Valle FH, J\u00fanior FP, Corsetti LC, Wainstein RV, Wainstein MV: Gastrointestinal Bleeding due to Angiodysplasia in a Patient with Severe Aortic Stenosis: Heyde's Syndrome. Rev Bras Cardiol Invasiva 2013; 21: 288-290.","DOI":"10.1016\/S2214-1235(15)30146-0"},{"key":"13","doi-asserted-by":"crossref","unstructured":"13. Ohta S, Watanabe T, Morita S, Ueno S, Tsuji Y, Nakase H, Chiba T: Massive jejunal bleeding due to Heyde syndrome successfully treated with double balloon endoscopy. Clin J Gastroenterol 2009; 2: 187-189.","DOI":"10.1007\/s12328-009-0069-9"},{"key":"14","doi-asserted-by":"crossref","unstructured":"14. Correa PL, Felix RCM, Azevedo JC, Silva PR, Oliveira AC Jr, Cortes D, Dohmann HF, Mesquita CT: Gastrointestinal Bleeding Diagnosed by Red Blood Cell Scintigraphy in a Patient With Aortic Stenosis: A Case of Heyde Syndrome. Clin Nucl Med 2005; 30: 231-235.","DOI":"10.1097\/01.rlu.0000155984.14938.28"},{"key":"15","doi-asserted-by":"crossref","unstructured":"15. Vincentelli A, Susen S, Tourneau TL, Six I, Fabre O, Juthier F, Bauters A, Decoene C, Goudemand J, Prat A, Jude B: Acquired von Willebrand Syndrome in Aortic Stenosis. N Engl J Med 2003; 349: 343-349.","DOI":"10.1056\/NEJMoa022831"},{"key":"16","doi-asserted-by":"crossref","unstructured":"16. Greenstein RJ, McElhinney AJ, Reuben D, Greenstein AJ: Colonic vascular ectasias and aortic stenosis: coincidence or causal relationship? Am J Surg 1986; 151: 347-351.","DOI":"10.1016\/0002-9610(86)90465-4"},{"key":"17","doi-asserted-by":"crossref","unstructured":"17. Rauch R, Budde U, Koch A, Girisch M, Hofbeck M: Acquired von Willebrand syndrome in children with patent ductus arteriosus. Heart 2002; 88: 87-88.","DOI":"10.1136\/heart.88.1.87"},{"key":"18","doi-asserted-by":"crossref","unstructured":"18. Thompson JL 3rd, Schaff HV, Dearani JA, Park SJ, Sundt TM 3rd, Suri RM, Blackshear JL, Daly RC: Risk of recurrent gastrointestinal bleeding after aortic valve replacement in patients with Heyde syndrome. J Thorac Cardiovasc Surg 2012; 144: 112-116.","DOI":"10.1016\/j.jtcvs.2011.05.034"},{"key":"19","doi-asserted-by":"crossref","unstructured":"19. Undas A, Natorska J: Bleeding in Patients With Severe Aortic Stenosis in the Era of Transcatheter Aortic Valve Replacement. JACC Cardiovasc Interv 2015; 8: 701-703.","DOI":"10.1016\/j.jcin.2015.03.001"},{"key":"20","doi-asserted-by":"crossref","unstructured":"20. Sami SS, Al Araji SA, Ragunath K: Review article: gastrointestinal angiodysplasia - pathogenesis, diagnosis and management. Aliment Pharmacol Ther 2014; 39: 15-34.","DOI":"10.1111\/apt.12527"}],"container-title":["Journal of Nippon Medical School"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/jnms\/84\/4\/84_193\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,26]],"date-time":"2025-06-26T00:30:16Z","timestamp":1750897816000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/jnms\/84\/4\/84_193\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017]]},"references-count":20,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2017]]}},"URL":"https:\/\/doi.org\/10.1272\/jnms.84.193","relation":{},"ISSN":["1345-4676","1347-3409"],"issn-type":[{"value":"1345-4676","type":"print"},{"value":"1347-3409","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017]]}}}