{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T18:23:03Z","timestamp":1790446983021,"version":"4.1.0"},"reference-count":0,"publisher":"Komitet Redakcyjno - Wydawniczy Polskiego Towarzystwa Psychiatrycznego","issue":"4","license":[{"start":{"date-parts":[[2019,8,31]],"date-time":"2019-08-31T00:00:00Z","timestamp":1567209600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2019,8,31]],"date-time":"2019-08-31T00:00:00Z","timestamp":1567209600000},"content-version":"am","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2019,8,31]],"date-time":"2019-08-31T00:00:00Z","timestamp":1567209600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Psychiatr Pol"],"published-print":{"date-parts":[[2019,8,31]]},"abstract":"<jats:p>Zaburzenie obsesyjno-kompulsyjne (Obsessive-Compulsive Disorder - OCD) wyst\u0119puje u oko\u0142o 2-3% populacji.  W zwi\u0105zku przewlek\u0142ym przebiegiem i du\u017cym procentem oporno\u015bci na standardowe leczenie poszukuje si\u0119 alternatywnego post\u0119powania klinicznego bazuj\u0105cego na osi\u0105gni\u0119ciach neuroscience.  G\u0142\u0119boka stymulacja m\u00f3zgu (DBS - Deep Brain Stimulation) jest nowoczesn\u0105 i dynamicznie rozwijaj\u0105c\u0105 si\u0119 metod\u0105, stwarzaj\u0105c\u0105 szanse na pomoc pacjentom opornym na dotychczasowe leczenie oparte na farmakoterapii i psychoterapii. W niniejszym opracowaniu przedstawiamy dwa przypadki pacjent\u00f3w z rozpoznaniem opornego na leczenie OCD, u kt\u00f3rych zastosowano terapi\u0119 DBS z jednoczesn\u0105 farmakoterapi\u0105 i psychoterapi\u0105 kognitywno- poznawcz\u0105 (CBT). U obojga pacjent\u00f3w przeprowadzono zabieg neurochirurgiczny z implantacj\u0105 elektrod do przedniej odnogi torebki wewn\u0119trznej (ALIC) oraz j\u0105dra p\u00f3\u0142le\u017c\u0105cego (NAc). Przed i po rozpocz\u0119ciu stymulacji prowadzono regularn\u0105 ewaluacj\u0119 kliniczn\u0105 w oparciu o badanie psychiatryczne oraz pomiary psychometryczne (Y-BOCS, HAMA, HDRS, GAF, SOFAS). W trakcie okresu obserwacji wykonano ponadto za\u015blepion\u0105 pr\u00f3b\u0119 wy\u0142\u0105czenia stymulacji. W okresie 6 miesi\u0119cznej obserwacji uzyskano znaczn\u0105 redukcj\u0119 w zakresie objaw\u00f3w obsesyjno-kompulsyjnych, depresyjnych, l\u0119kowych oraz poprawi\u0142o si\u0119 funkcjonowanie pacjent\u00f3w. Tolerancja terapii DBS by\u0142a bardzo dobra i nie stwierdzono istotnych objaw\u00f3w niepo\u017c\u0105danych. Uzyskane wyniki daj\u0105 podstawy do wdra\u017cania tej metody u innych, opornych na dotychczasowe leczenie pacjent\u00f3w z OCD.<\/jats:p>","DOI":"10.12740\/pp\/104643","type":"journal-article","created":{"date-parts":[[2019,9,14]],"date-time":"2019-09-14T13:40:03Z","timestamp":1568468403000},"page":"807-824","source":"Crossref","is-referenced-by-count":11,"title":["Deep brain stimulation in obsessive-compulsive disorder \u2013 case report of two patients"],"prefix":"10.12740","volume":"53","author":[{"given":"Jan","family":"Besz\u0142ej","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7480-5520","authenticated-orcid":false,"given":"Damian","family":"Siwicki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karolina","family":"Fila-Witecka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomasz","family":"Wieczorek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patryk","family":"Piotrowski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Artur","family":"Weiser","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pawe\u0142","family":"Tabakow","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joanna","family":"Rymaszewska","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"5036","published-online":{"date-parts":[[2019,8,31]]},"container-title":["Psychiatria Polska"],"original-title":["G\u0142\u0119boka stymulacja m\u00f3zgu w zaburzeniu obsesyjno-kompulsyjnym \u2013 dwa przypadki kliniczne"],"link":[{"URL":"https:\/\/www.psychiatriapolska.pl\/pdf-104643-81570","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.psychiatriapolska.pl\/pdf-104643-81570","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,10,18]],"date-time":"2022-10-18T06:51:45Z","timestamp":1666075905000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.psychiatriapolska.pl\/Deep-brain-stimulation-in-obsessive-compulsive-disorder-case-report-of-two-patients,104643,0,2.html"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,8,31]]},"references-count":0,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2019]]}},"alternative-id":["104643"],"URL":"https:\/\/doi.org\/10.12740\/pp\/104643","relation":{},"ISSN":["0033-2674","2391-5854"],"issn-type":[{"value":"0033-2674","type":"print"},{"value":"2391-5854","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,8,31]]}}}