{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,11]],"date-time":"2026-05-11T13:07:42Z","timestamp":1778504862180,"version":"3.51.4"},"reference-count":0,"publisher":"Komitet Redakcyjno - Wydawniczy Polskiego Towarzystwa Psychiatrycznego","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Psychiatr Pol"],"published-print":{"date-parts":[[2017,4,30]]},"abstract":"Cel pracy<\/jats:title>Podj\u0119to pr\u00f3b\u0119 oceny mineralizacji ko\u015bci i cz\u0119sto\u015bci z\u0142ama\u0144 u kobiet, kt\u00f3re w okresie dorastania by\u0142y leczone z powodu jad\u0142owstr\u0119tu psychicznego ( j.p.).<\/jats:p><\/jats:sec>Metoda<\/jats:title>47 kobiet (wiek 20-36,8lat) zbadano ponownie po 6,33-21,2latach od pojawienia si\u0119 objaw\u00f3w j.p. U 46 kobiet zbadano g\u0119sto\u015b\u0107 mineraln\u0105 ko\u015bci (BMD) ca\u0142ego szkieletu, kr\u0119gos\u0142upa l\u0119d\u017awiowego, szyjki ko\u015bci udowej, bli\u017cszego ko\u0144ca ko\u015bci udowej oraz dokonano densytometrycznej oceny z\u0142ama\u0144 kr\u0119gos\u0142upa (VFA). Oznaczenia BAP, P1NP, CTX, estradiolu, testosteronu, kortyzolu, IGF-1, leptyny, DHEA-S wykonano u 45 kobiet uczestnicz\u0105cych w obecnym badaniu. Aktualne wyniki BMD por\u00f3wnano z dost\u0119pnymi wynikami z okresu hospitalizacji.<\/jats:p><\/jats:sec>Wyniki<\/jats:title>Obecnie obni\u017cone BMD (Z-score<-1) w kt\u00f3rejkolwiek z badanych lokalizacji wyst\u0119powa\u0142o u 28 z 46 kobiet (w tym Z-score<-2 u 5-ciu). U 11 z 12-tu kobiet z obni\u017conym w okresie hospitalizacji BMD ca\u0142ego szkieletu obecnie wyniki mie\u015bci\u0142y si\u0119 w granicach normy. W zakresie kr\u0119gos\u0142upa l\u0119d\u017awiowego normalizacja lub poprawa wynik\u00f3w wyst\u0105pi\u0142a odpowiednio u 5 i 6 z 15-tu kobiet. Podwy\u017cszone st\u0119\u017cenie\/aktywno\u015b\u0107 marker\u00f3w tworzenia ko\u015bci P1NP i BAP stwierdzono obecnie odpowiednio u 27 (60%) i 28 kobiet (62,2%). U 7 (15,5%) kobiet stwierdzono jednocze\u015bnie podwy\u017cszone st\u0119\u017cenie markera resorpcji ko\u015bci (CTX). Podczas okresu obserwacji nie zaobserwowano wyst\u0119powania z\u0142ama\u0144 osteoporotycznych oraz z\u0142ama\u0144 kr\u0119gos\u0142upa metod\u0105 VFA.<\/jats:p><\/jats:sec>Wnioski<\/jats:title>Pomimo wczesnego rozpocz\u0119cia i dobrych wynik\u00f3w leczenia j.p. w okresie dorastania obni\u017cone BMD wyst\u0119powa\u0142o obecnie u 60,9% kobiet. Podczas obserwacji w wi\u0119kszo\u015bci przypadk\u00f3w obserwowano znacz\u0105c\u0105 popraw\u0119 lub normalizacj\u0119 wcze\u015bniej obni\u017conych wynik\u00f3w BMD ca\u0142ego szkieletu i kr\u0119gos\u0142upa l\u0119d\u017awiowego.<\/jats:p><\/jats:sec>","DOI":"10.12740\/pp\/63149","type":"journal-article","created":{"date-parts":[[2017,5,1]],"date-time":"2017-05-01T06:53:41Z","timestamp":1493621621000},"page":"231-246","source":"Crossref","is-referenced-by-count":3,"title":["Bone mineralization and densitometric evaluation of vertebral fractures in women 6\u201321 years after the onset of anorexia nervosa symptoms"],"prefix":"10.12740","volume":"51","author":[{"given":"Gabriela","family":"Jagielska","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jerzy","family":"Przedlacki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zbigniew","family":"Bartoszewicz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Agnieszka","family":"Kondracka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Agnieszka","family":"Butwicka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ewa","family":"Racicka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Olgierd","family":"Rowi\u0144ski","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rafa\u0142","family":"Brzewski","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomasz","family":"Wola\u0144czyk","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Celina","family":"Tomaszewicz-Libudzic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Urszula","family":"Szyma\u0144ska","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"5036","published-online":{"date-parts":[[2017,4,30]]},"container-title":["Psychiatria Polska"],"original-title":["Mineralizacja ko\u015bci i ocena densytometryczna z\u0142ama\u0144 kr\u0119gos\u0142upa u kobiet po up\u0142ywie 6\u201321 lat od pojawienia si\u0119 objaw\u00f3w jad\u0142owstr\u0119tu psychicznego"],"link":[{"URL":"https:\/\/www.psychiatriapolska.pl\/pdf-63149-81355","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.psychiatriapolska.pl\/pdf-63149-81355","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,10,18]],"date-time":"2022-10-18T06:57:24Z","timestamp":1666076244000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.psychiatriapolska.pl\/Mineralizacja-kosci-i-ocena-densytometryczna-zlaman-kregoslupa-u-kobiet-po-uplywie-6-21-lat-od-pojawienia-sie-objawow-jadlowstretu-psychicznego,63149,0,2.html"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,4,30]]},"references-count":0,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2017]]}},"alternative-id":["63149"],"URL":"https:\/\/doi.org\/10.12740\/pp\/63149","relation":{},"ISSN":["0033-2674","2391-5854"],"issn-type":[{"value":"0033-2674","type":"print"},{"value":"2391-5854","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,4,30]]}}}