{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,10,19]],"date-time":"2022-10-19T04:32:22Z","timestamp":1666153942133},"reference-count":0,"publisher":"Komitet Redakcyjno - Wydawniczy Polskiego Towarzystwa Psychiatrycznego","issue":"3","license":[{"start":{"date-parts":[[2021,6,30]],"date-time":"2021-06-30T00:00:00Z","timestamp":1625011200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2021,6,30]],"date-time":"2021-06-30T00:00:00Z","timestamp":1625011200000},"content-version":"am","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2021,6,30]],"date-time":"2021-06-30T00:00:00Z","timestamp":1625011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Psychiatr Pol"],"published-print":{"date-parts":[[2021,6,30]]},"abstract":"<jats:p>Ot\u0119pienie z cia\u0142ami Lewy'ego jak r\u00f3wnie\u017c choroba Creutzfeldta- Jakoba rozpoznawane s\u0105 na podstawie okre\u015blonych kryteri\u00f3w diagnostycznych. Jednak\u017ce wsp\u00f3lne objawy dla obu chor\u00f3b  takie jak : zesp\u00f3\u0142 ot\u0119pienny, zesp\u00f3\u0142 pozapiramidowy, zaburzenia psychotyczne mog\u0105 sprawia\u0107 trudno\u015bci diagnostyczne zw\u0142aszcza w pocz\u0105tkowej fazie choroby. Ka\u017cda z tych chor\u00f3b mo\u017ce mie\u0107 nietypowy pocz\u0105tek, a dopiero dalszy jej przebieg i pojawienie si\u0119 kolejnych objaw\u00f3w wskazuje w\u0142a\u015bciwe rozpoznanie. Pomocne w diagnostyce r\u00f3\u017cnicowej s\u0105 badania dodatkowe, przede wszystkim elektroencefalogram, badanie p\u0142ynu m\u00f3zgowo-rdzeniowego pod k\u0105tem bia\u0142ka 14-3-3.\nPrzedstawiamy przypadek 66-letniej pacjentki, u kt\u00f3rej pocz\u0105tkowo podejrzewali\u015bmy ot\u0119pienie z cia\u0142ami Lewy'ego. Przy przyj\u0119ciu w badaniu neurologicznym stwierdzono spowolnienie psychoruchowe, dyzartri\u0119, niewielk\u0105 dysmetri\u0119 ko\u0144czyn g\u00f3rnych, wzmo\u017cone pozapiramidowo napi\u0119cie w ko\u0144czynach g\u00f3rnych , ataksj\u0119 ko\u0144czyn dolnych,  powolny ch\u00f3d, chwiejn\u0105 pr\u00f3b\u0119 Romberga. W skali przesiewowej MMSE 24 punkty, w badaniu neuropsychologicznym: pocz\u0105tkowe stadium ot\u0119pienia, objawy l\u0119kowo-depresyjne z okresowymi elementami wytw\u00f3rczymi  wzrokowo-s\u0142uchowymi. Po niespe\u0142na 3 tygodniach nast\u0105pi\u0142o pogorszenie stanu neurologicznego: stwierdzono wi\u0119ksze spowolnienie psychoruchowe, nasilenie dyzartrii, wyst\u0105pienie ataksji tu\u0142owia oraz nasilenie ataksji ko\u0144czyn dolnych. Stwierdzono r\u00f3wnie\u017c znaczn\u0105 progresj\u0119 zaburze\u0144 poznawczych, pe\u0142ne badanie neuropsychologiczne by\u0142o  niemo\u017cliwe do wykonania, spadek w MMSE z 24 do 12 punkt\u00f3w.\nPrzebieg choroby u naszej pacjentki oraz wyniki bada\u0144 dodatkowych potwierdzi\u0142y obecno\u015b\u0107 sporadycznej postaci choroby Creutzfeldta- Jakoba.<\/jats:p>","DOI":"10.12740\/pp\/onlinefirst\/110915","type":"journal-article","created":{"date-parts":[[2019,11,24]],"date-time":"2019-11-24T08:44:21Z","timestamp":1574585061000},"page":"621-627","source":"Crossref","is-referenced-by-count":0,"title":["Creutzfeldt-Jakob disease mimicking Lewy body dementia \u2013 a case report"],"prefix":"10.12740","volume":"55","author":[{"given":"Marta","family":"Nesteruk","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomasz","family":"Nesteruk","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marzena","family":"U\u0142amek-Kozio\u0142","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna","family":"Holak-Puczy\u0144ska","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ma\u0142gorzata","family":"Dorobek","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"5036","published-online":{"date-parts":[[2021,6,30]]},"container-title":["Psychiatria Polska"],"original-title":["Choroba Creutzfeldta-Jakoba o pocz\u0105tkowym przebiegu na\u015bladuj\u0105cym ot\u0119pienie z cia\u0142ami Lewy\u2019ego \u2013 opis przypadku"],"link":[{"URL":"https:\/\/www.psychiatriapolska.pl\/pdf-110915-81741","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.psychiatriapolska.pl\/pdf-110915-81741","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,10,18]],"date-time":"2022-10-18T06:49:37Z","timestamp":1666075777000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.psychiatriapolska.pl\/Creutzfeldt-Jakob-disease-mimicking-Lewy-body-dementia-a-case-report,110915,0,2.html"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,6,30]]},"references-count":0,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2021]]}},"alternative-id":["110915"],"URL":"https:\/\/doi.org\/10.12740\/pp\/onlinefirst\/110915","relation":{},"ISSN":["0033-2674","2391-5854"],"issn-type":[{"value":"0033-2674","type":"print"},{"value":"2391-5854","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,6,30]]}}}