{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,8]],"date-time":"2026-05-08T19:01:48Z","timestamp":1778266908792,"version":"3.51.4"},"reference-count":0,"publisher":"Komitet Redakcyjno - Wydawniczy Polskiego Towarzystwa Psychiatrycznego","issue":"5","license":[{"start":{"date-parts":[[2022,10,31]],"date-time":"2022-10-31T00:00:00Z","timestamp":1667174400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2022,10,31]],"date-time":"2022-10-31T00:00:00Z","timestamp":1667174400000},"content-version":"am","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2022,10,31]],"date-time":"2022-10-31T00:00:00Z","timestamp":1667174400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Psychiatr Pol"],"published-print":{"date-parts":[[2022,10,31]]},"abstract":"<jats:sec><jats:title>Cel pracy<\/jats:title><jats:p>Cel: ocena zmian w zakresie obj\u0119to\u015bci istoty szarej w grupie adolescent\u00f3w z ASD, spe\u0142niaj\u0105cych kryteria dla zespo\u0142u Aspergera.<\/jats:p><\/jats:sec><jats:sec><jats:title>Metoda<\/jats:title><jats:p>Materia\u0142 i metoda: Badania morfometryczne oparte o pomiar voksela (Voxel Based Morphometry) wykonano u 37 nastolatk\u00f3w p\u0142ci m\u0119skiej, w wieku od 12 do 19 lat (\u015br. 14,3 \u00b1 2,0), z zaburzeniami ze spektrum autyzmu, kt\u00f3rzy spe\u0142niali kryteria DSM-IV-TR dla zespo\u0142u Aspergera oraz 15 prawid\u0142owo rozwijaj\u0105cych si\u0119 nastolatk\u00f3w dobranych pod wzgl\u0119dem wieku. Analizy statystyczne przeprowadzono na poziomie p&lt;0,05 z korekcj\u0105 FWE (family-wise error) oraz p&lt;0,007 bez korekcji FWE.<\/jats:p><\/jats:sec><jats:sec><jats:title>Wyniki<\/jats:title><jats:p>Wyniki: w grupie ASD wykazano zmniejszenie obj\u0119to\u015bci istoty szarej w zakr\u0119cie przed\u015brodkowym i za\u015brodkowym, g\u00f3rnym i \u015brodkowym zakr\u0119cie czo\u0142owym, g\u00f3rnym i dolnym p\u0142aciku ciemieniowym, przedklinku, przedniej i tylnej korze obr\u0119czy, zakr\u0119cie wrzecionowatym, zakr\u0119cie parahipokampalnym, zakr\u0119cie j\u0119zykowatym, \u015brodkowym obszarze potylicznym, klinku i zakr\u0119cie k\u0105towym, okolicach bruzd ostrogowych oraz m\u00f3\u017cd\u017cku; wi\u0119kszo\u015b\u0107 zmian by\u0142a zlokalizowana obustronnie.<\/jats:p><\/jats:sec><jats:sec><jats:title>Wnioski<\/jats:title><jats:p>Wnioski: zmniejszenie obj\u0119to\u015bci istoty szarej w grupie os\u00f3b z ASD w obszarach kory m\u00f3zgowej, kt\u00f3re funkcjonalnie mo\u017cna powi\u0105za\u0107 z charakterem deficyt\u00f3w obserwowanych w zaburzeniach ze spektrum autyzmu, podkre\u015bla rol\u0119 nieprawid\u0142owej budowy licznych struktur OUN w powstawaniu objaw\u00f3w obserwowanych w sferze poznawczej i behawioralnej.<\/jats:p><\/jats:sec>","DOI":"10.12740\/pp\/onlinefirst\/132704","type":"journal-article","created":{"date-parts":[[2021,4,21]],"date-time":"2021-04-21T15:31:18Z","timestamp":1619019078000},"page":"1049-1059","source":"Crossref","is-referenced-by-count":8,"title":["Morphometric evaluations based on Voxel Based Morphometry on adolescents with autism spectrum disorders."],"prefix":"10.12740","volume":"56","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9814-0818","authenticated-orcid":false,"given":"Anita","family":"Bry\u0144ska","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomasz","family":"Wolak","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patrycja","family":"Naumczyk","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomasz","family":"Srebnicki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomasz","family":"Wola\u0144czyk","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"5036","published-online":{"date-parts":[[2022,10,31]]},"container-title":["Psychiatria Polska"],"original-title":["Badania morfometryczne oparte o pomiar voksela (Voxel Based Morphometry) u nastolatk\u00f3w z zaburzeniami ze spektrum autyzmu"],"link":[{"URL":"https:\/\/www.psychiatriapolska.pl\/pdf-132704-81880","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.psychiatriapolska.pl\/pdf-132704-81880","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,12,5]],"date-time":"2022-12-05T21:41:29Z","timestamp":1670276489000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.psychiatriapolska.pl\/Morphometric-evaluations-based-on-Voxel-Based-Morphometry-on-adolescents-with-autism,132704,0,2.html"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,10,31]]},"references-count":0,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2022]]}},"alternative-id":["132704"],"URL":"https:\/\/doi.org\/10.12740\/pp\/onlinefirst\/132704","relation":{},"ISSN":["0033-2674","2391-5854"],"issn-type":[{"value":"0033-2674","type":"print"},{"value":"2391-5854","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,10,31]]}}}