{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T15:35:14Z","timestamp":1790696114940,"version":"4.1.0"},"reference-count":0,"publisher":"Komitet Redakcyjno - Wydawniczy Polskiego Towarzystwa Psychiatrycznego","issue":"2","license":[{"start":{"date-parts":[[2023,4,30]],"date-time":"2023-04-30T00:00:00Z","timestamp":1682812800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2023,4,30]],"date-time":"2023-04-30T00:00:00Z","timestamp":1682812800000},"content-version":"am","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2023,4,30]],"date-time":"2023-04-30T00:00:00Z","timestamp":1682812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Psychiatr Pol"],"published-print":{"date-parts":[[2023,4,30]]},"abstract":"<jats:p>Celem przegl\u0105du systematycznego by\u0142o okre\u015blenie: (1) r\u00f3\u017cnic pomi\u0119dzy pacjentami z AN a osobami zdrowymi  (HC) w sk\u0142adzie mikrobioty jelitowej i markerach zwi\u0105zanych z barier\u0105 jelitow\u0105, (2) Zwi\u0105zku mi\u0119dzy mikro\u015brodowiskiem jelit a zmiennymi zwi\u0105zanymi ze stanem zdrowia pacjent\u00f3w z AN. Dokonano przegl\u0105du pi\u015bmiennictwa (bazy danych PubMed \/ Embase \/ ClinicalTrials) do 30 wrze\u015bnia 2020 w poszukiwaniu bada\u0144 opisuj\u0105cych mikrobiom jelitowy i markery integralno\u015bci bariery jelitow\u0105 u pacjent\u00f3w z AN. Sze\u015b\u0107 bada\u0144 dotycz\u0105cych ekosystemu jelitowego zosta\u0142o zakwalifikowanych do przegl\u0105du, z czego trzy prace opisywa\u0142y r\u00f3wnie\u017c markery bariery jelitowej. Spo\u015br\u00f3d pi\u0119ciu bada\u0144 analizuj\u0105cych r\u00f3\u017cnorodno\u015b\u0107 mikrobioty, cztery z nich wykaza\u0142y r\u00f3\u017cnice mi\u0119dzy pacjentami z AN a osobami zdrowymi (HC). Badania potwierdzi\u0142y istnienie nieprawid\u0142owych warto\u015bci st\u0119\u017ce\u0144 marker\u00f3w integralno\u015bci bariery jelitowej pacjent\u00f3w z anoreksj\u0105. Przeprowadzony przegl\u0105d systematyczny potwierdza zmiany w ekosystemie jelitowym pacjent\u00f3w z zaburzeniami od\u017cywiania, jednak bez uzyskania konsensusu co do charakterystycznego dla AN wzorca mikrobioty. Uszkodzenie integralno\u015bci bariery jelitowej w tej grupie chorych  wymaga potwierdzenia w dalszych badaniach.<\/jats:p>","DOI":"10.12740\/pp\/onlinefirst\/140069","type":"journal-article","created":{"date-parts":[[2022,3,5]],"date-time":"2022-03-05T08:50:27Z","timestamp":1646470227000},"page":"355-374","source":"Crossref","is-referenced-by-count":5,"title":["Gut microbiota and intestinal barrier-related markers in patients  with anorexia nervosa: Systematic review"],"prefix":"10.12740","volume":"57","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7090-0977","authenticated-orcid":false,"given":"Joanna","family":"Rog","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karolina","family":"Skonieczna-\u017bydecka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dariusz","family":"Juchnowicz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olga","family":"Pada\u0142a","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Igor","family":"\u0141oniewski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barbara","family":"Budzy\u0144ska","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hanna","family":"Karakula-Juchnowicz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"5036","published-online":{"date-parts":[[2023,4,30]]},"container-title":["Psychiatria Polska"],"original-title":["Mikrobiota jelitowa i markery zwi\u0105zane z integralno\u015bci\u0105 bariery jelitowej u pacjent\u00f3w z jad\u0142owstr\u0119tem psychicznym: przegl\u0105d systematyczny"],"link":[{"URL":"https:\/\/www.psychiatriapolska.pl\/pdf-140069-81841","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.psychiatriapolska.pl\/pdf-140069-81841","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,30]],"date-time":"2023-05-30T19:11:47Z","timestamp":1685473907000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.psychiatriapolska.pl\/Gut-microbiota-and-intestinal-barrier-related-markers-in-patients-with-anorexia-nervosa,140069,0,2.html"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,4,30]]},"references-count":0,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2023]]}},"alternative-id":["140069"],"URL":"https:\/\/doi.org\/10.12740\/pp\/onlinefirst\/140069","relation":{},"ISSN":["0033-2674","2391-5854"],"issn-type":[{"value":"0033-2674","type":"print"},{"value":"2391-5854","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,4,30]]}}}