{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T15:36:57Z","timestamp":1787240217635,"version":"build-2736575974"},"reference-count":0,"publisher":"Komitet Redakcyjno - Wydawniczy Polskiego Towarzystwa Psychiatrycznego","issue":"6","license":[{"start":{"date-parts":[[2024,12,31]],"date-time":"2024-12-31T00:00:00Z","timestamp":1735603200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2024,12,31]],"date-time":"2024-12-31T00:00:00Z","timestamp":1735603200000},"content-version":"am","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2024,12,31]],"date-time":"2024-12-31T00:00:00Z","timestamp":1735603200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Psychiatr Pol"],"published-print":{"date-parts":[[2024,12,31]]},"abstract":"<jats:p>W rozumieniu teorii relacji z obiektem, zaburzenie osobowo\u015bci borderline (borderline personality disorder, BPD) charakteryzuje si\u0119 strukturaln\u0105 nieprawid\u0142owo\u015bci\u0105 to\u017csamo\u015bci, sprzecznymi reprezentacjami siebie i innych oraz dezorganizacj\u0105 przywi\u0105zania \u2013 konstruktu zakorzenionego we wczesnych do\u015bwiadczeniach jednostki, kluczowego dla nawi\u0105zywanych w p\u00f3\u017aniejszym \u017cyciu relacji. Szczeg\u00f3ln\u0105 rol\u0119 w powstawaniu stylu przywi\u0105zania przypisuje si\u0119 relacji z opiekunem, trudnym do\u015bwiadczeniom b\u0105d\u017a traumom z wczesnych etap\u00f3w rozwojowych. Do\u015bwiadczenia te stanowi\u0105 nie tylko psychologiczne pod\u0142o\u017ce rozwoju pozabezpiecznego stylu przywi\u0105zania, ale r\u00f3wnie\u017c pozostawiaj\u0105 w organizmie biologiczny \u015blad w postaci modyfikacji epigenetycznych. Cho\u0107 badania dotycz\u0105ce modyfikacji epigenetycznych w BPD nie s\u0105 liczne, rosn\u0105ca ilo\u015b\u0107 dowod\u00f3w ukazuje znaczenie w etiologii BPD oksytocyny  -  \u201e socjalnego peptydu \u201d le\u017c\u0105cego u podstaw przywi\u0105zania. Uwa\u017camy, \u017ce badania modyfikacji epigenetycznych wp\u0142ywaj\u0105cych na dzia\u0142anie oksytocyny w grupie klinicznej BPD pozwol\u0105 na lepsze zrozumienie pod\u0142o\u017ca i procesu rozwoju zaburzenia, a tak\u017ce wska\u017c\u0105 kierunek terapeutyczny pozwalaj\u0105cy na skuteczn\u0105 prac\u0119 w najwa\u017cniejszych obszarach BPD.<\/jats:p>","DOI":"10.12740\/pp\/onlinefirst\/166492","type":"journal-article","created":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T13:31:12Z","timestamp":1690896672000},"page":"997-1011","source":"Crossref","is-referenced-by-count":4,"title":["Borderline personality \u2013 from psychoanalysis to epigenetics. Biological basis of attachment"],"prefix":"10.12740","volume":"58","author":[{"given":"Ma\u0142gorzata","family":"Jura\u015b-Darowny","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dominik","family":"Strzelecki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3451-1250","authenticated-orcid":false,"given":"Monika","family":"Talarowska","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"5036","published-online":{"date-parts":[[2024,12,31]]},"container-title":["Psychiatria Polska"],"original-title":["Osobowo\u015b\u0107 borderline \u2013 od psychoanalizy do epigenetyki. Biologiczne pod\u0142o\u017ce wi\u0119zi"],"link":[{"URL":"https:\/\/www.psychiatriapolska.pl\/pdf-166492-94751","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.psychiatriapolska.pl\/pdf-166492-94751","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,20]],"date-time":"2025-01-20T01:16:06Z","timestamp":1737335766000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.psychiatriapolska.pl\/Borderline-personality-from-psychoanalysis-to-epigenetics-Biological-basis-of-attachment,166492,0,2.html"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12,31]]},"references-count":0,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2024]]}},"alternative-id":["166492"],"URL":"https:\/\/doi.org\/10.12740\/pp\/onlinefirst\/166492","relation":{},"ISSN":["0033-2674","2391-5854"],"issn-type":[{"value":"0033-2674","type":"print"},{"value":"2391-5854","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,12,31]]}}}