{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T11:21:28Z","timestamp":1789730488144,"version":"4.0.1"},"reference-count":0,"publisher":"Komitet Redakcyjno - Wydawniczy Polskiego Towarzystwa Psychiatrycznego","issue":"2","license":[{"start":{"date-parts":[[2025,4,30]],"date-time":"2025-04-30T00:00:00Z","timestamp":1745971200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,4,30]],"date-time":"2025-04-30T00:00:00Z","timestamp":1745971200000},"content-version":"am","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,4,30]],"date-time":"2025-04-30T00:00:00Z","timestamp":1745971200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Psychiatr Pol"],"published-print":{"date-parts":[[2025,4,30]]},"abstract":"<jats:sec><jats:title>Cel pracy<\/jats:title><jats:p>Wst\u0119p: Fibromialgia (FM) cz\u0119sto wsp\u00f3\u0142wyst\u0119puje z zaburzeniami psychicznymi. Ponadto, kilka badan wskazuje, \u017ce zaburzenia psychiczne mog\u0105 by\u0107 zwi\u0105zane z nasileniem i wp\u0142ywem FM. Celem naszej pracy by\u0142o po pierwsze: oceni\u0107 r\u00f3\u017cne wymiary objaw\u00f3w psychopatologicznych w\u015br\u00f3d pacjent\u00f3w z FM i po drugie: zbada\u0107 zale\u017cno\u015bci pomi\u0119dzy psychopatologi\u0105 a odpowiedzi\u0105 na leczenie inhibitorami wychwytu zwrotnego serotoniny i noradrenaliny (serotonin and noradrenaline reuptake inhibitors - SNRI).<\/jats:p><\/jats:sec><jats:sec><jats:title>Metoda<\/jats:title><jats:p>Metoda: Niniejsze badanie przekrojowe przeprowadzono pomi\u0119dzy grudniem 2020 i listopadem 2022. Oporno\u015b\u0107 na SNRI zdefiniowano jako  &lt;30% redukcj\u0119 b\u00f3lu po \u22658 tygodniach leczenia. W\u0142\u0105czono 30 pacjent\u00f3w z FM odpowiadaj\u0105cych na SNRI (FM T[+]), 32 pacjent\u00f3w nieodpowiadaj\u0105cych na SNRI (FM T[-]) i 30 zdrowych ochotnik\u00f3w. Uczestnicy byli badani przez lekarzy i wype\u0142niali narz\u0119dzia samooceny mierz\u0105ce poziom depresji (Kr\u00f3tki Inwentarz Symptomatologii Depresji, Szpitalna Skala L\u0119ku i Depresji), l\u0119ku (inwentarz Stanu i Cechy L\u0119ku), anhedonii (Skala Przyjemno\u015bci Snatih\u2019a-Hamiltona), dwubiegunowo\u015bci (Kwestionariusz Zaburze\u0144 Nastroju, Skala Hipomanii) i dysocjacji (Skala Do\u015bwiadcze\u0144 Dysocjacyjnych - wersja poprawiona). Aby oceni\u0107 zwi\u0105zki zmiennych psychopatologicznych i odpowiedzi na SNRI przeprowadzono analizy ANOVA i seri\u0119 prostych regresji logistycznych.<\/jats:p><\/jats:sec><jats:sec><jats:title>Wyniki<\/jats:title><jats:p>Wyniki: FM T[-] vs. FM T[+] ujawniali wy\u017cszy poziom depresji, cechy i stanu l\u0119ku, anhedonii i wy\u017csze proporcje wynik\u00f3w wskazuj\u0105cych na obecno\u015b\u0107 zaburze\u0144 l\u0119kowych. Wi\u0119ksze nasilenie depresji, l\u0119ku i anhedonii by\u0142y predyktorami oporno\u015bci na SNRI.<\/jats:p><\/jats:sec><jats:sec><jats:title>Wnioski<\/jats:title><jats:p>Wnioski: Modyfikowalne objawy psychopatologiczne r\u00f3\u017cni\u0105 pacjent\u00f3w FM T[+] vs. FM[-] i s\u0105 predyktorami oporno\u015bci na SNRI. Ocena psychologiczna powinna by\u0107 cz\u0119\u015bci\u0105 standardowej opieki nad osobami z FM.<\/jats:p><\/jats:sec>","DOI":"10.12740\/pp\/onlinefirst\/176000","type":"journal-article","created":{"date-parts":[[2024,2,3]],"date-time":"2024-02-03T20:27:09Z","timestamp":1706992029000},"page":"175-192","source":"Crossref","is-referenced-by-count":9,"title":["Psychopathological symptoms in fibromyalgia and their associations with resistance to pharmacotherapy with SNRI"],"prefix":"10.12740","volume":"59","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3291-9663","authenticated-orcid":false,"given":"Anna Julia","family":"Krupa","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2107-9980","authenticated-orcid":false,"given":"Adrian Andrzej","family":"Chrobak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0656-8505","authenticated-orcid":false,"given":"Zbigniew","family":"So\u0142tys","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1749-9739","authenticated-orcid":false,"given":"Mariusz","family":"Korkosz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8748-7581","authenticated-orcid":false,"given":"Jaroslaw","family":"Nowakowski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6120-0506","authenticated-orcid":false,"given":"Dominika","family":"Dudek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3109-1895","authenticated-orcid":false,"given":"Marcin","family":"Siwek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"5036","published-online":{"date-parts":[[2025,4,30]]},"container-title":["Psychiatria Polska"],"original-title":["Objawy psychopatologiczne w fibromialgii i ich zwi\u0105zki z oporno\u015bci\u0105 na farmakoterapi\u0119 z zastosowaniem SNRI"],"link":[{"URL":"https:\/\/www.psychiatriapolska.pl\/pdf-176000-106777","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.psychiatriapolska.pl\/pdf-176000-106777","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T21:28:53Z","timestamp":1748813333000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.psychiatriapolska.pl\/Psychopathological-symptoms-in-fibromyalgia-and-their-associations-with-resistance,176000,0,2.html"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4,30]]},"references-count":0,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2025]]}},"alternative-id":["176000"],"URL":"https:\/\/doi.org\/10.12740\/pp\/onlinefirst\/176000","relation":{},"ISSN":["0033-2674","2391-5854"],"issn-type":[{"value":"0033-2674","type":"print"},{"value":"2391-5854","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,4,30]]}}}