{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,9]],"date-time":"2026-05-09T08:16:10Z","timestamp":1778314570063,"version":"3.51.4"},"reference-count":0,"publisher":"Komitet Redakcyjno - Wydawniczy Polskiego Towarzystwa Psychiatrycznego","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Psychiatr Pol"],"abstract":"<jats:sec><jats:title>Cel<\/jats:title><jats:p>Pojedyncze doniesienia naukowe wskazuj\u0105 na zmiany st\u0119\u017cenia magnezu we krwi u os\u00f3b z chorob\u0105 afektywn\u0105 dwubiegunow\u0105 (ChAD), jednak dotychczas przeprowadzono bardzo niewiele bada\u0144 na temat tego zagadnienia. Celem przedstawionego badania by\u0142o przeprowadzenie oceny st\u0119\u017cenia magnezu w surowicy u chorych na ChAD w poszczeg\u00f3lnych fazach choroby i w por\u00f3wnaniu do zdrowych ochotnik\u00f3w<\/jats:p><\/jats:sec><jats:sec><jats:title>Metoda<\/jats:title><jats:p>Do badania zakwalifikowano 129 pacjent\u00f3w z rozpoznaniem ChAD (typ I i II), w tym 58 os\u00f3b w aktualnym epizodzie depresji, 23 osoby w aktualnym stanie maniakalnym i 48 pacjent\u00f3w znajduj\u0105cych si\u0119 w stanie remisji. Grupa kontrolna liczy\u0142a 50 os\u00f3b. Pomiaru st\u0119\u017cenia magnezu dokonano metod\u0105 p\u0142omieniowej atomowej spektrometrii absorpcyjnej (FAAS)<\/jats:p><\/jats:sec><jats:sec><jats:title>Wyniki<\/jats:title><jats:p>U pacjent\u00f3w b\u0119d\u0105cych w epizodzie depresyjnym oraz maniakalnym\/hipomaniakalnym  st\u0119\u017cenie magnezu w surowicy by\u0142o istotnie statystycznie wi\u0119ksze w por\u00f3wnaniu z grup\u0105 zdrowych ochotnik\u00f3w, oraz dodatnio skorelowane z czasem trwania epizodu manii\/hipomanii i liczb\u0105 zaostrze\u0144 choroby w ostatnim roku. St\u0119\u017cenie magnezu u pacjent\u00f3w znajduj\u0105cych si\u0119 w fazie remisji nie r\u00f3\u017cni\u0142o si\u0119 istotnie od st\u0119\u017cenia uzyskanego w grupie kontrolnej<\/jats:p><\/jats:sec><jats:sec><jats:title>Wnioski<\/jats:title><jats:p>Wyniki badania mog\u0105 sugerowa\u0107 rol\u0119 st\u0119\u017cenia magnezu jako markera stanu, odzwierciedlaj\u0105cego zmiany patofizjologiczne towarzysz\u0105ce ostrym epizodom CHAD<\/jats:p><\/jats:sec>","DOI":"10.12740\/pp\/onlinefirst\/42047","type":"journal-article","created":{"date-parts":[[2015,7,25]],"date-time":"2015-07-25T13:20:38Z","timestamp":1437830438000},"page":"1277-1287","source":"Crossref","is-referenced-by-count":15,"title":["The serum concentration of magnesium as a potential state marker in patients with diagnosis of bipolar disorder"],"prefix":"10.12740","volume":"49","author":[{"given":"Marcin","family":"Siwek","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Krzysztof","family":"Stycze\u0144","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Magdalena","family":"Sowa-Ku\u0107ma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dominika","family":"Dudek","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Witold","family":"Reczy\u0144ski","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bernadeta","family":"Szewczyk","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paulina","family":"Misztak","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"W\u0142odzimierz","family":"Opoka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roman","family":"Top\u00f3r-M\u0105dry","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gabriel","family":"Nowak","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"5036","published-online":{"date-parts":[[2015,12,31]]},"container-title":["Psychiatria Polska"],"original-title":["St\u0119\u017cenie magnezu w surowicy jako potencjalny marker stanu u pacjent\u00f3w z diagnoz\u0105 choroby afektywnej dwubiegunowej"],"link":[{"URL":"https:\/\/www.psychiatriapolska.pl\/pdf-58109-81235","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.psychiatriapolska.pl\/pdf-58109-81235","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,10,18]],"date-time":"2022-10-18T06:59:33Z","timestamp":1666076373000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.psychiatriapolska.pl\/Stezenie-magnezu-w-surowicy-jako-potencjalny-marker-stanu-u-pacjentow-z-diagnoza-choroby-afektywnej-dwubiegunowej,58109,0,2.html"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,12,31]]},"references-count":0,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2015]]}},"alternative-id":["58109"],"URL":"https:\/\/doi.org\/10.12740\/pp\/onlinefirst\/42047","relation":{},"ISSN":["0033-2674","2391-5854"],"issn-type":[{"value":"0033-2674","type":"print"},{"value":"2391-5854","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,12,31]]}}}