{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T02:51:20Z","timestamp":1787021480091,"version":"build-2736575974"},"reference-count":0,"publisher":"Komitet Redakcyjno - Wydawniczy Polskiego Towarzystwa Psychiatrycznego","issue":"1","license":[{"start":{"date-parts":[[2020,3,29]],"date-time":"2020-03-29T00:00:00Z","timestamp":1585440000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2020,3,29]],"date-time":"2020-03-29T00:00:00Z","timestamp":1585440000000},"content-version":"am","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2020,3,29]],"date-time":"2020-03-29T00:00:00Z","timestamp":1585440000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Psychiatr Pol"],"published-print":{"date-parts":[[2020,3,29]]},"abstract":"<jats:p>Choroba afektywna dwubiegunowa (ChAD) charakteryzuje si\u0119 patologicznymi zmianami nastroju i aktywno\u015bci o charakterze epizod\u00f3w maniakalnych, hipomaniakalnych, depresyjnych lub mieszanych. W ostatnich latach obserwuje si\u0119 znacz\u0105cy wzrost rozpoznawania ChAD u dzieci i m\u0142odzie\u017cy. Ocenia si\u0119, \u017ce \u015bredni wska\u017anik rozpowszechnienia spektrum zaburze\u0144 afektywnych w populacji pediatrycznej wynosi 1,8 %, a ChAD typu I \u2013 1,2%. Mimo jednakowych kryteri\u00f3w diagnostycznych istniej\u0105 przes\u0142anki, \u017ce niekt\u00f3re objawy choroby wyst\u0119puj\u0105 z inn\u0105 cz\u0119sto\u015bci\u0105 w\u015br\u00f3d dzieci i m\u0142odzie\u017cy ni\u017c u os\u00f3b doros\u0142ych.  Za najcz\u0119stszy objaw maniakalny u os\u00f3b z pocz\u0105tkiem choroby w wieku dzieci\u0119cym uwa\u017ca si\u0119 dra\u017cliwo\u015b\u0107, a w wieku m\u0142odzie\u0144czym - nadmiern\u0105 aktywno\u015b\u0107. ChAD w populacji dzieci i m\u0142odzie\u017cy towarzyszy wysoki wska\u017anik wsp\u00f3\u0142wyst\u0119powania innych chor\u00f3b psychicznych. Szczeg\u00f3lne problemy diagnostyczne stwarza zesp\u00f3\u0142 nadpobudliwo\u015bci ruchowej z deficytem uwagi oraz osobowo\u015b\u0107 borderline. Wczesny pocz\u0105tek ChAD wi\u0105\u017ce si\u0119 z ci\u0119\u017cszym przebiegiem, gorszym rokowaniem i wy\u017cszym ryzykiem samob\u00f3jczym. W leczeniu farmakologicznym ChAD w populacji pediatrycznej stosuje si\u0119 leki normotymiczne I i II generacji, przy czym ich skuteczno\u015b\u0107 oraz profil bezpiecze\u0144stwa r\u00f3\u017cni si\u0119 od os\u00f3b doros\u0142ych. Ameryka\u0144ski Food and Drug Administration rekomenduje w leczeniu epizod\u00f3w maniakalnych u m\u0142odych os\u00f3b lit, aripiprazol, kwetiapin\u0119, risperidon, olanzapin\u0119, a w przypadku epizod\u00f3w depresyjnych po\u0142\u0105czenie olanzapiny z fluoksetyn\u0105.<\/jats:p>","DOI":"10.12740\/pp\/onlinefirst\/92740","type":"journal-article","created":{"date-parts":[[2018,10,27]],"date-time":"2018-10-27T17:27:16Z","timestamp":1540661236000},"page":"35-50","source":"Crossref","is-referenced-by-count":41,"title":["Clinical picture and treatment of bipolar affective disorder in children and adolescents"],"prefix":"10.12740","volume":"54","author":[{"given":"Lena","family":"Cicho\u0144","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ma\u0142gorzata","family":"Janas-Kozik","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrzej","family":"Siwiec","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Janusz","family":"Rybakowski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"5036","published-online":{"date-parts":[[2020,3,29]]},"container-title":["Psychiatria Polska"],"original-title":["Obraz kliniczny i leczenie choroby afektywnej dwubiegunowej u dzieci i m\u0142odzie\u017cy"],"link":[{"URL":"https:\/\/www.psychiatriapolska.pl\/pdf-92740-81613","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.psychiatriapolska.pl\/pdf-92740-81613","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,10,18]],"date-time":"2022-10-18T02:50:59Z","timestamp":1666061459000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.psychiatriapolska.pl\/Clinical-picture-and-treatment-of-bipolar-affective-disorder-in-children-and-adolescents,92740,0,2.html"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,3,29]]},"references-count":0,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2020]]}},"alternative-id":["92740"],"URL":"https:\/\/doi.org\/10.12740\/pp\/onlinefirst\/92740","relation":{},"ISSN":["0033-2674","2391-5854"],"issn-type":[{"value":"0033-2674","type":"print"},{"value":"2391-5854","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,3,29]]}}}