{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T07:32:15Z","timestamp":1781076735628,"version":"3.54.1"},"reference-count":15,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2017,9,6]],"date-time":"2017-09-06T00:00:00Z","timestamp":1504656000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Hospital Medicine"],"published-print":{"date-parts":[[2017,10]]},"abstract":"<jats:p>The prevalence of psychiatric symptoms ranges from 17% to 44% in intensive care unit (ICU) survivors. The relationship between the comorbidity of psychiatric symptoms and quality of life (QoL) in ICU survivors has not been carefully examined. This study examined the relationship between psychiatric comorbidities and QoL in 58 survivors of ICU delirium. Patients completed 3 psychiatric screens at 3 months after discharge from the hospital, including the Patient Health Questionnaire\u20109 (PHQ\u20109) for depression, the Generalized Anxiety Disorder\u20107 (GAD\u20107) questionnaire for anxiety, and the Post\u2010Traumatic Stress Syndrome (PTSS\u201010) questionnaire for posttraumatic stress disorder. Patients with 3 positive screens (PHQ\u20109 \u2265 10; GAD\u20107 \u2265 10; and PTSS\u201010 &gt; 35) comprised the high psychiatric comorbidity group. Patients with 1 to 2 positive screens were labeled the low to moderate (low\u2010moderate) psychiatric comorbidity group. Patients with 3 negative screens were labeled the no psychiatric morbidity group. Thirty\u2010one percent of patients met the criteria for high psychiatric comorbidity. After adjusting for age, gender, Charlson Comorbidity Index, discharge status, and prior history of depression and anxiety, patients who had high psychiatric comorbidity were more likely to have a poorer QoL compared with the low\u2010moderate comorbidity and no morbidity groups, as measured by a lower EuroQol 5 dimensions questionnaire 3\u2010level Index (no, 0.69 \u00b1 0.25; low\u2010moderate, 0.70 \u00b1 0.19; high, 0.48 \u00b1 0.24; <jats:italic>P<\/jats:italic> = 0.017). Future studies should confirm these findings and examine whether survivors of ICU delirium with high psychiatric comorbidity have different treatment needs from survivors with lower psychiatric comorbidity.<\/jats:p>","DOI":"10.12788\/jhm.2827","type":"journal-article","created":{"date-parts":[[2017,10,16]],"date-time":"2017-10-16T16:52:19Z","timestamp":1508172739000},"page":"831-835","source":"Crossref","is-referenced-by-count":37,"title":["Post\u2010Intensive Care Unit Psychiatric Comorbidity and Quality of Life"],"prefix":"10.1002","volume":"12","author":[{"given":"Sophia","family":"Wang","sequence":"first","affiliation":[{"name":"Department of Psychiatry Indiana University School of Medicine Indianapolis Indiana"},{"name":"Roudebush VA Medical Center Indianapolis Indiana"},{"name":"Center of Health Innovation and Implementation Science Center for Translational Science and Innovation Indianapolis Indiana"},{"name":"Sandra Eskenazi Center for Brain Care Innovation Eskenazi Hospital Indianapolis Indiana"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chris","family":"Mosher","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Indiana University School of Medicine Indianapolis Indiana"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anthony J.","family":"Perkins","sequence":"additional","affiliation":[{"name":"Center of Health Innovation and Implementation Science Center for Translational Science and Innovation Indianapolis Indiana"},{"name":"Indiana Clinical and Translational Research Institute Indiana University School of Medicine Indianapolis Indiana"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sujuan","family":"Gao","sequence":"additional","affiliation":[{"name":"Department of Biostatistics Indiana University School of Medicine Indianapolis Indiana"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sue","family":"Lasiter","sequence":"additional","affiliation":[{"name":"University of Missouri\u2010Kansas City School of Nursing and Health Studies Kansas City Missouri"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sikandar","family":"Khan","sequence":"additional","affiliation":[{"name":"Division of Pulmonary Critical Care, Sleep and Occupational Medicine Department of Internal Medicine Indiana University School of Medicine Indianapolis Indiana"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Malaz","family":"Boustani","sequence":"additional","affiliation":[{"name":"Sandra Eskenazi Center for Brain Care Innovation Eskenazi Hospital Indianapolis Indiana"},{"name":"Division of Geriatrics and General Internal Medicine Department of Internal Medicine Indiana University School of Medicine Indianapolis Indiana"},{"name":"Indiana University Center of Aging Research Regenstrief Institute Indianapolis Indiana"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Babar","family":"Khan","sequence":"additional","affiliation":[{"name":"Division of Pulmonary Critical Care, Sleep and Occupational Medicine Department of Internal Medicine Indiana University School of Medicine Indianapolis Indiana"},{"name":"Indiana University Center of Aging Research Regenstrief Institute Indianapolis 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