{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T04:56:40Z","timestamp":1784696200205,"version":"3.55.0"},"reference-count":18,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2020,9,23]],"date-time":"2020-09-23T00:00:00Z","timestamp":1600819200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["shmpublications.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Hospital Medicine"],"published-print":{"date-parts":[[2020,12]]},"abstract":"<jats:p>Children with complicated appendicitis, osteomyelitis, and complicated pneumonia have historically been treated with postdischarge intravenous antibiotics (PD\u2010IV) using peripherally inserted central catheters (PICCs). Recent studies have shown no advantage and increased complications of PD\u2010IV, compared with oral therapy, and the extent to which use of PD\u2010IV has since changed for these conditions is not known. We used a national children's hospital database to evaluate trends in PD\u2010IV during 2000\u20102018 for each of these three conditions. PD\u2010IV decreased from 13% to 2% (risk ratio [RR], 0.15; 95% CI, 0.14\u20100.16) for complicated appendicitis, 61% to 22% (RR, 0.41; 95% CI, 0.39\u20100.43) for osteomyelitis, and 29% to 19% (RR, 0.63; 95% CI, 0.58\u20100.69) for complicated pneumonia. Despite these overall reductions, substantial variation in PD\u2010IV use by hospital remains in 2018.<\/jats:p>","DOI":"10.12788\/jhm.3422","type":"journal-article","created":{"date-parts":[[2020,9,23]],"date-time":"2020-09-23T07:14:14Z","timestamp":1600845254000},"page":"731-733","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Trends in Use of Postdischarge Intravenous Antibiotic Therapy for Children"],"prefix":"10.1002","volume":"15","author":[{"given":"Michael E","family":"Fenster","sequence":"first","affiliation":[{"name":"Department of Pediatrics University of Utah School of Medicine Salt Lake City Utah"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adam L","family":"Hersh","sequence":"additional","affiliation":[{"name":"Department of Pediatrics University of Utah School of Medicine Salt Lake City 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