{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T10:35:30Z","timestamp":1791110130423,"version":"4.1.0"},"reference-count":36,"publisher":"American Chemical Society (ACS)","issue":"9","license":[{"start":{"date-parts":[[2017,12,29]],"date-time":"2017-12-29T00:00:00Z","timestamp":1514505600000},"content-version":"vor","delay-in-days":2374,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2011,9,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Background: Polybrominated diphenyl ethers (PBDEs) have been widely used as flame retardants in consumer products and are ubiquitous in residential indoor air and dust. However, little is known about exposure in the office environment.<\/jats:p>\n                  <jats:p>Objectives: We examined relationships between PBDE concentrations in the office environment and internal exposure using concurrent measurements of PBDEs in serum, handwipes, and office dust.<\/jats:p>\n                  <jats:p>Methods: We collected serum, dust, and handwipe samples from 31 participants who spent at least 20 hr\/week in an office. We used a questionnaire to collect information about work and personal habits.<\/jats:p>\n                  <jats:p>Results: We found positive associations between PBDEs in room dust, handwipes (a measure of personal exposure), and serum. PBDE office dust concentrations were weakly correlated with measurements in handwipes: r = 0.35 (p = 0.06) for pentaBDE (sum of BDE congeners 28\/33, 47, 99, 100, and 153) and 0.33 (p = 0.07) for BDE-209. Hand washing also predicted pentaBDE levels in handwipes: low hand-washers had 3.3 times the pentaBDE levels in their handwipes than did high hand-washers (p = 0.02). PentaBDE in handwipes predicted pentaBDE levels in serum (p = 0.03): Serum concentrations in the highest handwipe tertile were on average 3.5 times the lowest handwipe tertile. The geometric mean concentration of pentaBDEs in serum was 27 ng\/g lipid. We detected BDE-209 in 20% of serum samples, at levels ranging from &amp;lt; 4.8 to 9.7 ng\/g lipid.<\/jats:p>\n                  <jats:p>Conclusion: Our research suggests that exposure to pentaBDE in the office environment contributes to pentaBDE body burden, with exposure likely linked to PBDE residues on hands. In addition, hand washing may decrease exposure to PBDEs.<\/jats:p>","DOI":"10.1289\/ehp.1003271","type":"journal-article","created":{"date-parts":[[2011,6,29]],"date-time":"2011-06-29T22:24:55Z","timestamp":1309386295000},"page":"1247-1252","source":"Crossref","is-referenced-by-count":182,"title":["Exposure to PBDEs in the Office Environment: Evaluating the Relationships Between Dust, Handwipes, and Serum"],"prefix":"10.1021","volume":"119","author":[{"given":"Deborah J.","family":"Watkins","sequence":"first","affiliation":[{"name":"Department of Environmental Health, and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael D.","family":"McClean","sequence":"additional","affiliation":[{"name":"Department of Environmental Health, and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alicia J.","family":"Fraser","sequence":"additional","affiliation":[{"name":"Department of Environmental Health, and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Janice","family":"Weinberg","sequence":"additional","affiliation":[{"name":"Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heather M.","family":"Stapleton","sequence":"additional","affiliation":[{"name":"Nicholas School of the Environment, Duke University, Durham, North Carolina, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas","family":"Sj\u00f6din","sequence":"additional","affiliation":[{"name":"Division for Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, Georgia, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas F.","family":"Webster","sequence":"additional","affiliation":[{"name":"Department of Environmental Health, and"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2011,6,30]]},"reference":[{"issue":"4","key":"2026080610025477600_micit1","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1007\/s00128-008-9370-4","article-title":"Polybrominated diphenyl ethers in human serum and sperm quality.","volume":"80","author":"Akutsu","year":"2008","journal-title":"Bull Environ Contam Toxicol"},{"issue":"13","key":"2026080610025477600_micit2","doi-asserted-by":"crossref","first-page":"4574","DOI":"10.1021\/es0703170","article-title":"Personal exposure to polybrominated diphenyl ethers (PBDEs) in residential indoor air.","volume":"41","author":"Allen","year":"2007","journal-title":"Environ Sci Technol"},{"issue":"8","key":"2026080610025477600_micit3","doi-asserted-by":"crossref","first-page":"1085","DOI":"10.1016\/j.envint.2008.03.006","article-title":"Critical factors in assessing exposure to PBDEs via house dust.","volume":"34","author":"Allen","year":"2008","journal-title":"Environ Int"},{"issue":"6","key":"2026080610025477600_micit4","doi-asserted-by":"crossref","first-page":"548","DOI":"10.1016\/j.envint.2010.04.008","article-title":"Brominated flame retardants in offices in Michigan, USA.","volume":"36","author":"Batterman","year":"2010","journal-title":"Environ Int"},{"key":"2026080610025477600_micit5","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1289\/ehp.6559","article-title":"Brominated flame retardants: cause for concern?","volume":"112","author":"Birnbaum","year":"2004","journal-title":"Environ Health Perspect"},{"key":"2026080610025477600_micit6","article-title":"Regulation of Upholstered Furniture: BFD IX-10","author":"Boston Fire Department","year":"1995"},{"issue":"2","key":"2026080610025477600_micit7","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1016\/j.envint.2006.09.013","article-title":"Levels of polybrominated diphenyl ethers (PBDEs) in breast milk from central Taiwan and their relation to infant birth outcome and maternal menstruation effects.","volume":"33","author":"Chao","year":"2007","journal-title":"Environ Int"},{"issue":"7","key":"2026080610025477600_micit8","doi-asserted-by":"crossref","first-page":"1371","DOI":"10.1016\/j.atmosenv.2007.10.080","article-title":"Indoor pollutants emitted by office equipment: a review of reported data and information needs.","volume":"42","author":"Destaillats","year":"2008","journal-title":"Atmos Environ"},{"key":"2026080610025477600_micit9","doi-asserted-by":"crossref","first-page":"1520","DOI":"10.1289\/ehp.0900817","article-title":"Diet contributes significantly to the body burden of PBDEs in the general U.S. population.","volume":"117","author":"Fraser","year":"2009","journal-title":"Environ Health Perspect"},{"issue":"4","key":"2026080610025477600_micit10","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/j.ijheh.2010.04.008","article-title":"Polybrominated diphenyl ethers in paired samples of maternal and umbilical cord blood plasma and associations with house dust in a Danish cohort.","volume":"213","author":"Frederiksen","year":"2010","journal-title":"Int J Hyg Environ Health"},{"issue":"2","key":"2026080610025477600_micit11","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/j.ijheh.2008.04.005","article-title":"Human internal and external exposure to PBDEs\u2014a review of levels and sources.","volume":"212","author":"Frederiksen","year":"2009","journal-title":"Int J Hyg Environ Health"},{"issue":"8","key":"2026080610025477600_micit12","doi-asserted-by":"crossref","first-page":"1125","DOI":"10.1016\/j.envint.2009.07.003","article-title":"Human exposure to polybrominated diphenyl ethers (PBDE), as evidenced by data from a duplicate diet study, indoor air, house dust, and biomonitoring in Germany.","volume":"35","author":"Fromme","year":"2009","journal-title":"Environ Int"},{"key":"2026080610025477600_micit13","first-page":"3867","article-title":"Terminal elimination half-lives of the brominated flame retardants TBBPA, HBCD, and lower brominated PBDEs in humans.","volume":"66","author":"Geyer","year":"2004","journal-title":"Organohalogen Compounds"},{"key":"2026080610025477600_micit14","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1289\/ehp.0901450","article-title":"PBDE concentrations in women\u2019s serum and fecundability.","volume":"118","author":"Harley","year":"2010","journal-title":"Environ Health Perspect"},{"issue":"8","key":"2026080610025477600_micit15","doi-asserted-by":"crossref","first-page":"1170","DOI":"10.1016\/j.envint.2008.05.001","article-title":"Concentrations of brominated flame retardants in dust from United Kingdom cars, homes, and offices: causes of variability and implications for human exposure.","volume":"34","author":"Harrad","year":"2008","journal-title":"Environ Int"},{"key":"2026080610025477600_micit16","doi-asserted-by":"crossref","first-page":"712","DOI":"10.1289\/ehp.0901340","article-title":"Prenatal exposure to PBDEs and neurodevelopment.","volume":"118","author":"Herbstman","year":"2010","journal-title":"Environ Health Perspect"},{"issue":"2","key":"2026080610025477600_micit17","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/j.chemosphere.2009.09.061","article-title":"PBDEs in indoor dust in south-central China: characteristics and implications.","volume":"78","author":"Huang","year":"2010","journal-title":"Chemosphere"},{"issue":"14","key":"2026080610025477600_micit18","doi-asserted-by":"crossref","first-page":"5627","DOI":"10.1021\/es100697q","article-title":"Relationships between polybrominated diphenyl ether concentrations in house dust and serum.","volume":"44","author":"Johnson","year":"2010","journal-title":"Environ Sci Technol"},{"key":"2026080610025477600_micit19","doi-asserted-by":"crossref","first-page":"1519","DOI":"10.1289\/ehp.9924","article-title":"Flame retardants in placenta and breast milk and cryptorchidism in newborn boys.","volume":"115","author":"Main","year":"2007","journal-title":"Environ Health Perspect"},{"issue":"10","key":"2026080610025477600_micit20","doi-asserted-by":"crossref","first-page":"3425","DOI":"10.1016\/j.scitotenv.2009.01.030","article-title":"Polybrominated diphenyl ether (PBDE) concentrations in house dust are related to hormone levels in men.","volume":"407","author":"Meeker","year":"2009","journal-title":"Sci Total Environ"},{"issue":"4","key":"2026080610025477600_micit21","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1016\/j.envint.2010.02.005","article-title":"Exposure of the Flemish population to brominated flame retardants: model and risk assessment.","volume":"36","author":"Roosens","year":"2010","journal-title":"Environ Int"},{"key":"2026080610025477600_micit22","doi-asserted-by":"crossref","first-page":"1953","DOI":"10.1289\/ehp.0901015","article-title":"Prenatal exposure to organohalogens, including brominated flame retardants, influences motor, cognitive, and behavioral performance at school age.","volume":"117","author":"Roze","year":"2009","journal-title":"Environ Health Perspect"},{"key":"2026080610025477600_micit23","first-page":"654","article-title":"Retrospective time-trend study of polybrominated diphenyl ether and polybrominated and polychlorinated biphenyl levels in human serum from the United States.","volume":"112","author":"Sj\u00f6din","year":"2004","journal-title":"Environ Health Perspect"},{"issue":"4","key":"2026080610025477600_micit24","doi-asserted-by":"crossref","first-page":"1377","DOI":"10.1021\/es702451p","article-title":"Serum concentrations of polybrominated diphenyl ethers (PBDEs) and polybrominated biphenyl (PBB) in the United States population: 2003\u20132004.","volume":"42","author":"Sj\u00f6din","year":"2008","journal-title":"Environ Sci Technol"},{"issue":"4","key":"2026080610025477600_micit25","doi-asserted-by":"crossref","first-page":"925","DOI":"10.1021\/es0486824","article-title":"Polybrominated diphenyl ethers in house dust and clothes dryer lint.","volume":"39","author":"Stapleton","year":"2005","journal-title":"Environ Sci Technol"},{"issue":"9","key":"2026080610025477600_micit26","doi-asserted-by":"crossref","first-page":"3329","DOI":"10.1021\/es7029625","article-title":"Measurement of polybrominated diphenyl ethers on hand wipes: estimating exposure from hand-to-mouth contact.","volume":"42","author":"Stapleton","year":"2008","journal-title":"Environ Sci Technol"},{"key":"2026080610025477600_micit27","unstructured":"Stockholm Convention\n          . 2010. The 9 New POPs Under the Stockholm Convention.Available: http:\/\/chm.pops.int\/Implementation\/NewPOPs\/The9newPOPs\/tabid\/672\/language\/en-US\/Default.aspx [accessed 4 March 2011]."},{"key":"2026080610025477600_micit28","first-page":"1843","article-title":"PBDEs and PBDD\/Fs in house and office dust from Japan.","volume":"68","author":"Suzuki","year":"2006","journal-title":"Organohalogen Compounds"},{"issue":"2","key":"2026080610025477600_micit29","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/j.chemosphere.2009.03.057","article-title":"Assessment of polybrominated diphenyl ethers (PBDEs) in samples collected from indoor environments in South East Queensland, Australia.","volume":"76","author":"Toms","year":"2009","journal-title":"Chemosphere"},{"key":"2026080610025477600_micit30","article-title":"Exposure Factors Handbook","author":"U.S. EPA","year":"1997"},{"key":"2026080610025477600_micit31","unstructured":"U.S. EPA (Environmental Protection Agency)\n          . 2010. DecaBDE Phase-Out Initiative.Available: http:\/\/www.epa.gov\/oppt\/existingchemicals\/pubs\/actionplans\/deccadbe.html [accessed 4 March 2011]."},{"issue":"9","key":"2026080610025477600_micit32","doi-asserted-by":"crossref","first-page":"3067","DOI":"10.1021\/es803139w","article-title":"Identifying transfer mechanisms and sources of decabromodiphenyl ether (BDE 209) in indoor environments using environmental forensic microscopy.","volume":"43","author":"Webster","year":"2009","journal-title":"Environ Sci Technol"},{"issue":"40","key":"2026080610025477600_micit33","doi-asserted-by":"crossref","first-page":"9018","DOI":"10.1016\/j.atmosenv.2008.09.052","article-title":"Semivolatile organic compounds in indoor environments.","volume":"42","author":"Weschler","year":"2008","journal-title":"Atmos Environ"},{"issue":"5","key":"2026080610025477600_micit34","doi-asserted-by":"crossref","first-page":"1584","DOI":"10.1021\/es0620282","article-title":"Human exposure to PBDEs: associations of PBDE body burdens with food consumption and house dust concentrations.","volume":"41","author":"Wu","year":"2007","journal-title":"Environ Sci Technol"},{"issue":"8","key":"2026080610025477600_micit35","doi-asserted-by":"crossref","first-page":"2845","DOI":"10.1021\/es802172a","article-title":"Multimedia modeling of polybrominated diphenyl ether emissions and fate indoors.","volume":"43","author":"Zhang","year":"2009","journal-title":"Environ Sci Technol"},{"issue":"21","key":"2026080610025477600_micit36","doi-asserted-by":"crossref","first-page":"8158","DOI":"10.1021\/es801792z","article-title":"Elevated house dust and serum concentrations of PBDEs in California: unintended consequences of furniture flammability standards?","volume":"42","author":"Zota","year":"2008","journal-title":"Environ Sci Technol"}],"container-title":["Environmental Health Perspectives"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/evhpaz\/article-pdf\/119\/9\/1247\/66443867\/ehp.1003271.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/pubs.acs.org\/evhpaz\/article-pdf\/119\/9\/1247\/66443867\/ehp.1003271.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T13:49:40Z","timestamp":1786628980000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/evhpaz\/article-lookup\/doi\/10.1289\/ehp.1003271"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,6,30]]},"references-count":36,"journal-issue":{"issue":"9","published-online":{"date-parts":[[2011,6,30]]},"published-print":{"date-parts":[[2011,9,1]]}},"URL":"https:\/\/doi.org\/10.1289\/ehp.1003271","relation":{},"ISSN":["0091-6765","1552-9924"],"issn-type":[{"value":"0091-6765","type":"print"},{"value":"1552-9924","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,6,30]]}}}