{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T20:21:49Z","timestamp":1791145309086,"version":"4.1.0"},"reference-count":36,"publisher":"American Chemical Society (ACS)","issue":"1","license":[{"start":{"date-parts":[[2017,12,29]],"date-time":"2017-12-29T00:00:00Z","timestamp":1514505600000},"content-version":"vor","delay-in-days":3728,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2008,1,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Recent studies have identified associations between the concentration of phthalates in indoor dust and allergic symptoms in the airways, nose, and skin.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>Our goal was to investigate the associations between allergic symptoms in children and the concentration of phthalate esters in settled dust collected from children\u2019s homes in Sofia and Burgas, Bulgaria.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Dust samples from the child\u2019s bedroom were collected. A total of 102 children (2\u20137 years of age) had symptoms of wheezing, rhinitis, and\/or eczema in preceding 12 months (cases), and 82 were nonsymptomatic (controls). The dust samples were analyzed for their content of dimethyl phthalate (DMP), diethyl phthalate (DEP), di-n-butyl phthalate (DnBP), butyl benzyl phthalate (BBzP), di(2-ethylhexyl) phthalate (DEHP), and di-n-octyl phthalate (DnOP).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A higher concentration of DEHP was found in homes of case children than in those of controls (1.24 vs. 0.86 mg\/g dust). The concentration of DEHP was significantly associated with wheezing in the preceding 12 months (p = 0.035) as reported by parents. We found a dose\u2013response relationship between DEHP concentration and case status and between DEHP concentration and wheezing in the preceding 12 months.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>This study shows an association between concentration of DEHP in indoor dust and wheezing among preschool children in Bulgaria.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1289\/ehp.10498","type":"journal-article","created":{"date-parts":[[2007,10,15]],"date-time":"2007-10-15T13:13:02Z","timestamp":1192453982000},"page":"98-103","source":"Crossref","is-referenced-by-count":287,"title":["The Association between Phthalates in Dust and Allergic Diseases among Bulgarian Children"],"prefix":"10.1021","volume":"116","author":[{"given":"Barbara","family":"Kolarik","sequence":"first","affiliation":[{"name":"Technical University of Denmark, Department of Mechanical Engineering, International Centre for Indoor Environment and Energy, Lyngby, Denmark"},{"name":"Silesian University of Technology, Faculty of Environmental Engineering and Energy, Gliwice, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kiril","family":"Naydenov","sequence":"additional","affiliation":[{"name":"Technical University of Denmark, Department of Mechanical Engineering, International Centre for Indoor Environment and Energy, Lyngby, Denmark"},{"name":"Birch & Krogboe A\/S, Virum, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Malin","family":"Larsson","sequence":"additional","affiliation":[{"name":"Public Health Sciences, Karlstad University, Karlstad, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carl-Gustaf","family":"Bornehag","sequence":"additional","affiliation":[{"name":"Technical University of Denmark, Department of Mechanical Engineering, International Centre for Indoor Environment and Energy, Lyngby, Denmark"},{"name":"Public Health Sciences, Karlstad University, Karlstad, Sweden"},{"name":"SP-Technical Research Institute of Sweden, Boras, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan","family":"Sundell","sequence":"additional","affiliation":[{"name":"Technical University of Denmark, Department of Mechanical Engineering, International Centre for Indoor Environment and Energy, Lyngby, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2007,10,15]]},"reference":[{"key":"2026080312091510000_micit1","doi-asserted-by":"crossref","first-page":"1719","DOI":"10.1289\/ehp.6235","article-title":"Prenatal exposures to phthalates among women in New York City and Krakow, Poland","volume":"111","author":"Adibi","year":"2003","journal-title":"Environ Health 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