{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T06:53:21Z","timestamp":1791269601501,"version":"4.1.0"},"reference-count":55,"publisher":"American Chemical Society (ACS)","issue":"5","license":[{"start":{"date-parts":[[2017,12,29]],"date-time":"2017-12-29T00:00:00Z","timestamp":1514505600000},"content-version":"vor","delay-in-days":3628,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2008,5,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Evidence suggests that air pollution exposure adversely affects pregnancy outcomes. Few studies have examined individual-level intraurban exposure contrasts.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>We evaluated the impacts of air pollution on small for gestational age (SGA) birth weight, low full-term birth weight (LBW), and preterm birth using spatiotemporal exposure metrics.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>With linked administrative data, we identified 70,249 singleton births (1999\u20132002) with complete covariate data (sex, ethnicity, parity, birth month and year, income, education) and maternal residential history in Vancouver, British Columbia, Canada. We estimated residential exposures by month of pregnancy using nearest and inverse-distance weighting (IDW) of study area monitors [carbon monoxide, nitrogen dioxide, nitric oxide, ozone, sulfur dioxide, and particulate matter &amp;lt; 2.5 (PM2.5) or &amp;lt; 10 (PM10) \u03bcm in aerodynamic diameter], temporally adjusted land use regression (LUR) models (NO, NO2, PM2.5, black carbon), and proximity to major roads. Using logistic regression, we estimated the risk of mean (entire pregnancy, first and last month of pregnancy, first and last 3 months) air pollution concentrations on SGA (&amp;lt; 10th percentile), term LBW (&amp;lt; 2,500 g), and preterm birth.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Residence within 50 m of highways was associated with a 26% increase in SGA [95% confidence interval (CI), 1.07\u20131.49] and an 11% (95% CI, 1.01\u20131.23) increase in LBW. Exposure to all air pollutants except O3 was associated with SGA, with similar odds ratios (ORs) for LUR and monitoring estimates (e.g., LUR: OR = 1.02; 95% CI, 1.00\u20131.04; IDW: OR = 1.05; 95% CI, 1.03\u20131.08 per 10-\u03bcg\/m3 increase in NO). For preterm births, associations were observed with PM2.5 for births &amp;lt; 37 weeks gestation (and for other pollutants at &amp;lt; 30 weeks). No consistent patterns suggested exposure windows of greater relevance.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Associations between traffic-related air pollution and birth outcomes were observed in a population-based cohort with relatively low ambient air pollution exposure.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1289\/ehp.10952","type":"journal-article","created":{"date-parts":[[2008,1,21]],"date-time":"2008-01-21T14:22:08Z","timestamp":1200925328000},"page":"680-686","source":"Crossref","is-referenced-by-count":518,"title":["A Cohort Study of Traffic-Related Air Pollution Impacts on Birth Outcomes"],"prefix":"10.1021","volume":"116","author":[{"given":"Michael","family":"Brauer","sequence":"first","affiliation":[{"name":"School of Environmental Health"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cornel","family":"Lencar","sequence":"additional","affiliation":[{"name":"School of Environmental Health"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lillian","family":"Tamburic","sequence":"additional","affiliation":[{"name":"Centre for Health Services and Policy Research"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mieke","family":"Koehoorn","sequence":"additional","affiliation":[{"name":"School of Environmental Health"},{"name":"Department of Health Care and Epidemiology, The University of British Columbia, Vancouver, British Columbia, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"Demers","sequence":"additional","affiliation":[{"name":"School of Environmental Health"},{"name":"Department of Health Care and Epidemiology, The University of British Columbia, Vancouver, British Columbia, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine","family":"Karr","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, University of Washington, Seattle, Washington, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2008,1,23]]},"reference":[{"issue":"12","key":"2026080503043724800_micit1","doi-asserted-by":"crossref","first-page":"1190","DOI":"10.1093\/aje\/kwj338","article-title":"Living near main streets and respiratory symptoms in adults: the Swiss cohort study on air pollution and lung diseases in adults","volume":"164","author":"Bayer-Oglesby","year":"2006","journal-title":"Am J Epidemiol"},{"key":"2026080503043724800_micit2","doi-asserted-by":"crossref","first-page":"1414","DOI":"10.1289\/ehp.9089","article-title":"Traffic-related air pollution and otitis media","volume":"114","author":"Brauer","year":"2006","journal-title":"Environ Health 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Wheezing in infants living near truck and bus traffic","volume":"116","author":"Ryan","year":"2005","journal-title":"J Allergy Clin Immunol"},{"key":"2026080503043724800_micit47","doi-asserted-by":"crossref","first-page":"602","DOI":"10.1289\/ehp.7646","article-title":"A time-series analysis of air pollution and preterm birth in Pennsylvania, 1997\u20132001","volume":"113","author":"Sagiv","year":"2005","journal-title":"Environ Health Perspect"},{"key":"2026080503043724800_micit48","doi-asserted-by":"crossref","first-page":"1638","DOI":"10.1289\/ehp.8111","article-title":"Birth outcomes and prenatal exposure to ozone, carbon monoxide, and particulate matter: results from The Children\u2019s Health Study","volume":"113","author":"Salam","year":"2005","journal-title":"Environ Health Perspect"},{"key":"2026080503043724800_micit49","doi-asserted-by":"crossref","first-page":"1283","DOI":"10.1289\/ehp.10047","article-title":"Traffic-related atmospheric pollutants levels during pregnancy and offspring\u2019s term birth weight: a study relying on a land-use regression exposure model","volume":"115","author":"Slama","year":"2007","journal-title":"Environ Health Perspect"},{"issue":"6","key":"2026080503043724800_micit50","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1136\/jech.2005.037044","article-title":"Traffic intensity, dwelling value, and hospital admissions for respiratory disease among the elderly in Montreal (Canada): a case-control analysis","volume":"60","author":"Smargiassi","year":"2006","journal-title":"J Epidemiol Community Health"},{"key":"2026080503043724800_micit51","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1289\/ehp.6362","article-title":"Ambient air pollution and pregnancy outcomes: a review of the literature","volume":"113","author":"\u0160r\u00e1m","year":"2005","journal-title":"Environ Health Perspect"},{"key":"2026080503043724800_micit52","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1289\/ehp.5688","article-title":"Residential proximity to traffic and adverse birth outcomes in Los Angeles County, California, 1994\u20131996","volume":"111","author":"Wilhelm","year":"2003","journal-title":"Environ Health Perspect"},{"key":"2026080503043724800_micit53","doi-asserted-by":"crossref","first-page":"1212","DOI":"10.1289\/ehp.7751","article-title":"Local variations in CO and particulate air pollution and adverse birth outcomes in Los Angeles County, California, USA","volume":"113","author":"Wilhelm","year":"2005","journal-title":"Environ Health Perspect"},{"issue":"38","key":"2026080503043724800_micit54","doi-asserted-by":"crossref","first-page":"6655","DOI":"10.1016\/j.atmosenv.2004.06.044","article-title":"Evolution of particle number distribution near roadways. Part II: The \u2018road-to-ambient\u2019 process","volume":"38","author":"Zhang","year":"2004","journal-title":"Atmos Environ"},{"key":"2026080503043724800_micit55","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1080\/02786820390229156","article-title":"Seasonal trends of concentration and size distribution of ultrafine particles near major highways in Los Angeles","volume":"38","author":"Zhu","year":"2004","journal-title":"Aerosol Sci Technol"}],"container-title":["Environmental Health Perspectives"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/evhpaz\/article-pdf\/116\/5\/680\/66396541\/ehp.10952.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/pubs.acs.org\/evhpaz\/article-pdf\/116\/5\/680\/66396541\/ehp.10952.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T13:55:19Z","timestamp":1786629319000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/evhpaz\/article-lookup\/doi\/10.1289\/ehp.10952"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,1,23]]},"references-count":55,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2008,1,23]]},"published-print":{"date-parts":[[2008,5,1]]}},"URL":"https:\/\/doi.org\/10.1289\/ehp.10952","relation":{},"ISSN":["0091-6765","1552-9924"],"issn-type":[{"value":"0091-6765","type":"print"},{"value":"1552-9924","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,1,23]]}}}