{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T14:25:25Z","timestamp":1791123925603,"version":"4.1.0"},"reference-count":32,"publisher":"American Chemical Society (ACS)","issue":"2","license":[{"start":{"date-parts":[[2017,12,29]],"date-time":"2017-12-29T00:00:00Z","timestamp":1514505600000},"content-version":"vor","delay-in-days":2306,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2012,2,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Context: Exposure to air pollution can result in the onset of arrhythmias.<\/jats:p>\n                  <jats:p>Case presentation: We present a case of a 58-year-old woman who volunteered to participate in a controlled exposure to concentrated ambient particles. Twenty minutes into the exposure, telemetry revealed new onset of atrial fibrillation. The exposure was discontinued, and she reverted to normal sinus rhythm approximately 2 hr later. No abnormality was evident on the volunteer\u2019s laboratory examination or echocardiography that could explain an increased risk for supraventricular arrhythmia.<\/jats:p>\n                  <jats:p>Discussion: Epidemiologic evidence strongly supports a relationship between exposure to air pollutants and cardiovascular disease, but population-level data are not directly relevant to the clinical presentation of individual cases. To our knowledge, this is the only case report of an individual suffering an episode of atrial fibrillation after exposure to an air pollutant. The resolution of the arrhythmia with termination of the particle exposure further supports a causal relationship between the two.<\/jats:p>\n                  <jats:p>Relevance to clinical practice: Exposure to air pollution, including particulate matter, may cause supraventricular arrhythmias.<\/jats:p>","DOI":"10.1289\/ehp.1103877","type":"journal-article","created":{"date-parts":[[2011,9,6]],"date-time":"2011-09-06T15:07:13Z","timestamp":1315321633000},"page":"275-277","source":"Crossref","is-referenced-by-count":10,"title":["Case Report: Supraventricular Arrhythmia after Exposure to Concentrated Ambient Air Pollution Particles"],"prefix":"10.1021","volume":"120","author":[{"given":"Andrew J.","family":"Ghio","sequence":"first","affiliation":[{"name":"Environmental Public Health Division, National Health and Environmental Effects Research Laboratory, U.S. Environmental Protection Agency, Chapel Hill, North Carolina, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maryann","family":"Bassett","sequence":"additional","affiliation":[{"name":"Environmental Public Health Division, National Health and Environmental Effects Research Laboratory, U.S. Environmental Protection Agency, Chapel Hill, North Carolina, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tracey","family":"Montilla","sequence":"additional","affiliation":[{"name":"Environmental Public Health Division, National Health and Environmental Effects Research Laboratory, U.S. Environmental Protection Agency, Chapel Hill, North Carolina, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eugene H.","family":"Chung","sequence":"additional","affiliation":[{"name":"Division of Cardiology, University of North Carolina\u2013Chapel Hill, Chapel Hill, North Carolina, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Candice B.","family":"Smith","sequence":"additional","affiliation":[{"name":"Environmental Public Health Division, National Health and Environmental Effects Research Laboratory, U.S. Environmental Protection Agency, Chapel Hill, North Carolina, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wayne E.","family":"Cascio","sequence":"additional","affiliation":[{"name":"Environmental Public Health Division, National Health and Environmental Effects Research Laboratory, U.S. Environmental Protection Agency, Chapel Hill, North Carolina, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martha Sue","family":"Carraway","sequence":"additional","affiliation":[{"name":"Environmental Public Health Division, National Health and Environmental Effects Research Laboratory, U.S. Environmental Protection Agency, Chapel Hill, North Carolina, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2011,9,6]]},"reference":[{"issue":"11","key":"2026080507034141300_micit1","doi-asserted-by":"crossref","first-page":"1149","DOI":"10.1097\/01.jom.0000245921.15916.03","article-title":"Runs of ventricular and supraventricular tachycardia triggered by air pollution in patients with coronary heart disease.","volume":"48","author":"Berger","year":"2006","journal-title":"J Occup Environ Med"},{"issue":"17","key":"2026080507034141300_micit2","doi-asserted-by":"crossref","first-page":"1904","DOI":"10.1161\/CIRCULATIONAHA.109.874982","article-title":"Excessive supraventricular ectopic activity and increased risk of atrial fibrillation and stroke.","volume":"121","author":"Binici","year":"2010","journal-title":"Circulation"},{"issue":"11","key":"2026080507034141300_micit3","doi-asserted-by":"crossref","first-page":"1133","DOI":"10.1097\/01.jom.0000245675.85924.7e","article-title":"Personal coronary risk profiles modify autonomic nervous system responses to air pollution.","volume":"48","author":"Chen","year":"2006","journal-title":"J Occup Environ Med"},{"issue":"24","key":"2026080507034141300_micit4","doi-asserted-by":"crossref","first-page":"2886","DOI":"10.1161\/hc4901.101760","article-title":"C-reactive protein elevation in patients with atrial arrhythmias: inflammatory mechanisms and persistence of atrial fibrillation.","volume":"104","author":"Chung","year":"2001","journal-title":"Circulation"},{"issue":"suppl 4","key":"2026080507034141300_micit5","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1289\/ehp.01109s4483","article-title":"Epidemiologic evidence of cardiovascular effects of particulate air pollution.","volume":"109","author":"Dockery","year":"2001","journal-title":"Environ Health Perspect"},{"issue":"14","key":"2026080507034141300_micit6","doi-asserted-by":"crossref","first-page":"1067","DOI":"10.1056\/NEJM200104053441407","article-title":"Atrial fibrillation.","volume":"344","author":"Falk","year":"2001","journal-title":"N Engl J Med"},{"issue":"12","key":"2026080507034141300_micit7","doi-asserted-by":"crossref","first-page":"1549","DOI":"10.1164\/rccm.200412-1726OC","article-title":"A case-crossover analysis of out-of-hospital coronary deaths and air pollution in Rome, Italy.","volume":"172","author":"Forastiere","year":"2005","journal-title":"Am J Respir Crit Care Med"},{"issue":"suppl 1","key":"2026080507034141300_micit8","first-page":"II195","article-title":"The \u2013174G\/C interleukin-6 polymorphism influences postoperative interleukin-6 levels and postoperative atrial fibrillation. Is atrial fibrillation an inflammatory complication?","volume":"108","author":"Gaudino","year":"2003","journal-title":"Circulation"},{"key":"2026080507034141300_micit9","doi-asserted-by":"crossref","first-page":"951","DOI":"10.1289\/ehp.1003200","article-title":"TRPA1 and sympathetic activation contribute to increased risk of triggered cardiac arrhythmias in hypertensive rats exposed to diesel exhaust.","volume":"119","author":"Hazari","year":"2011","journal-title":"Environ Health Perspect"},{"issue":"4","key":"2026080507034141300_micit10","doi-asserted-by":"crossref","first-page":"1190","DOI":"10.1152\/jappl.1998.84.4.1190","article-title":"Exposing guinea pigs to ozone for 1 wk enhances responsiveness of rapidly adapting receptors.","volume":"84","author":"Joad","year":"1998","journal-title":"J Appl Physiol"},{"issue":"1","key":"2026080507034141300_micit11","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.mcna.2007.09.002","article-title":"Status of the epidemiology of atrial fibrillation.","volume":"92","author":"Kannel","year":"2008","journal-title":"Med Clin North Am"},{"issue":"1","key":"2026080507034141300_micit12","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.ccl.2008.09.015","article-title":"Current perceptions of the epidemiology of atrial fibrillation.","volume":"27","author":"Kannel","year":"2009","journal-title":"Cardiol Clin"},{"issue":"1","key":"2026080507034141300_micit13","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/j.cardiores.2004.01.018","article-title":"The HMG-CoA reductase inhibitor atorvastatin prevents atrial fibrillation by inhibiting inflammation in a canine sterile pericarditis model.","volume":"62","author":"Kumagai","year":"2004","journal-title":"Cardiovasc Res"},{"issue":"1","key":"2026080507034141300_micit14","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1080\/15287390802445483","article-title":"Ambient particulate air pollution and ectopy\u2014the environmental epidemiology of arrhythmogenesis in Women\u2019s Health Initiative Study, 1999\u20132004.","volume":"72","author":"Liao","year":"2009","journal-title":"J Toxicol Environ Health A"},{"issue":"1","key":"2026080507034141300_micit15","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1097\/HCO.0b013e32833358cd","article-title":"Air pollution and the triggering of cardiac arrhythmias.","volume":"25","author":"Link","year":"2010","journal-title":"Curr Opin Cardiol"},{"issue":"23","key":"2026080507034141300_micit16","doi-asserted-by":"crossref","first-page":"2894","DOI":"10.1093\/eurheartj\/ehn463","article-title":"Rapid effects of air pollution on ventricular arrhythmias.","volume":"29","author":"Ljungman","year":"2008","journal-title":"Eur Heart J"},{"issue":"5","key":"2026080507034141300_micit17","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1007\/s10565-010-9158-2","article-title":"Roles of oxidative stress in signaling and inflammation induced by particulate matter.","volume":"26","author":"Mazzoli-Rocha","year":"2010","journal-title":"Cell Biol Toxicol"},{"issue":"5","key":"2026080507034141300_micit18","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1097\/EDE.0b013e318124ff0e","article-title":"Ambient air pollution and cardiac arrhythmias in patients with implantable defibrillators.","volume":"18","author":"Metzger","year":"2007","journal-title":"Epidemiology"},{"issue":"11","key":"2026080507034141300_micit19","doi-asserted-by":"crossref","first-page":"1075","DOI":"10.1056\/NEJMoa066314","article-title":"Ischemic and thrombotic effects of dilute diesel-exhaust inhalation in men with coronary heart disease.","volume":"357","author":"Mills","year":"2007","journal-title":"N Engl J Med"},{"issue":"pt 1","key":"2026080507034141300_micit20","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1111\/j.1469-7793.2000.00223.x","article-title":"Chronic passive cigarette smoke exposure augments bronchopulmonary C-fibre inputs to nucleus tractus solitarii neurones and reflex output in young guinea-pigs.","volume":"523","author":"Mutoh","year":"2000","journal-title":"J Physiol"},{"issue":"1","key":"2026080507034141300_micit21","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1097\/00001648-200001000-00005","article-title":"Air pollution and incidence of cardiac arrhythmia.","volume":"11","author":"Peters","year":"2000","journal-title":"Epidemiology"},{"issue":"9","key":"2026080507034141300_micit22","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1136\/oem.2005.023457","article-title":"Association of ventricular arrhythmias detected by implantable cardioverter defibrillator and ambient air pollutants in the St Louis, Missouri metropolitan area.","volume":"63","author":"Rich","year":"2006","journal-title":"Occup Environ Med"},{"issue":"12","key":"2026080507034141300_micit23","doi-asserted-by":"crossref","first-page":"1123","DOI":"10.1093\/aje\/kwi143","article-title":"Association of short-term ambient air pollution concentrations and ventricular arrhythmias.","volume":"161","author":"Rich","year":"2005","journal-title":"Am J Epidemiol"},{"key":"2026080507034141300_micit24","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1289\/ehp.10757","article-title":"Out-of-hospital cardiac arrest and airborne fine particulate matter: a case-crossover analysis of emergency medical services data in Indianapolis, Indiana.","volume":"116","author":"Rosenthal","year":"2008","journal-title":"Environ Health Perspect"},{"issue":"6","key":"2026080507034141300_micit25","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1093\/occmed\/kqi136","article-title":"Air pollution and the heart.","volume":"55","author":"Routledge","year":"2005","journal-title":"Occup Med (Lond)"},{"issue":"3","key":"2026080507034141300_micit26","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1136\/jech.2006.058123","article-title":"Cardiac arrhythmia emergency room visits and environmental air pollution in Sao Paulo, Brazil.","volume":"62","author":"Santos","year":"2008","journal-title":"J Epidemiol Community Health"},{"issue":"10","key":"2026080507034141300_micit27","doi-asserted-by":"crossref","first-page":"700","DOI":"10.1136\/oem.2006.027292","article-title":"Ambient particulate air pollution and cardiac arrhythmia in a panel of older adults in Steubenville, Ohio.","volume":"63","author":"Sarnat","year":"2006","journal-title":"Occup Environ Med"},{"issue":"11","key":"2026080507034141300_micit28","doi-asserted-by":"crossref","first-page":"1343","DOI":"10.1016\/j.amjcard.2003.08.023","article-title":"Prevention of atrial fibrillation recurrence by statin therapy in patients with lone atrial fibrillation after successful cardioversion.","volume":"92","author":"Siu","year":"2003","journal-title":"Am J Cardiol"},{"key":"2026080507034141300_micit29","doi-asserted-by":"crossref","first-page":"560","DOI":"10.1289\/ehp.8337","article-title":"The relationship between ambient air pollution and heart rate variability differs for individuals with heart and pulmonary disease.","volume":"114","author":"Wheeler","year":"2006","journal-title":"Environ Health Perspect"},{"issue":"6","key":"2026080507034141300_micit30","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1093\/aje\/kwn400","article-title":"Heart rate variability, ambient particulate matter air pollution, and glucose homeostasis: the environmental epidemiology of arrhythmogenesis in the Women\u2019s Health Initiative.","volume":"169","author":"Whitsel","year":"2009","journal-title":"Am J Epidemiol"},{"key":"2026080507034141300_micit31","doi-asserted-by":"crossref","first-page":"978","DOI":"10.1289\/ehp.7550","article-title":"The effect of particulate air pollution on emergency admissions for myocardial infarction: a multicity case-crossover analysis.","volume":"113","author":"Zanobetti","year":"2005","journal-title":"Environ Health Perspect"},{"issue":"3","key":"2026080507034141300_micit32","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1080\/08958370802492407","article-title":"ECG parameters and exposure to carbon ultrafine particles in young healthy subjects.","volume":"21","author":"Zareba","year":"2009","journal-title":"Inhal Toxicol"}],"container-title":["Environmental Health Perspectives"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/evhpaz\/article-pdf\/120\/2\/275\/66404356\/ehp.1103877.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/pubs.acs.org\/evhpaz\/article-pdf\/120\/2\/275\/66404356\/ehp.1103877.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T13:56:36Z","timestamp":1786629396000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/evhpaz\/article-lookup\/doi\/10.1289\/ehp.1103877"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,9,6]]},"references-count":32,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2011,9,6]]},"published-print":{"date-parts":[[2012,2,1]]}},"URL":"https:\/\/doi.org\/10.1289\/ehp.1103877","relation":{},"ISSN":["0091-6765","1552-9924"],"issn-type":[{"value":"0091-6765","type":"print"},{"value":"1552-9924","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,9,6]]}}}