{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T02:07:59Z","timestamp":1791425279750,"version":"4.3.3"},"reference-count":38,"publisher":"American Chemical Society (ACS)","issue":"3","license":[{"start":{"date-parts":[[2017,12,29]],"date-time":"2017-12-29T00:00:00Z","timestamp":1514505600000},"content-version":"vor","delay-in-days":1787,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2013,3,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Background: A growing body of evidence has associated maternal exposure to air pollution with adverse effects on fetal growth; however, the existing literature is inconsistent.<\/jats:p>\n                  <jats:p>Objectives: We aimed to quantify the association between maternal exposure to particulate air pollution and term birth weight and low birth weight (LBW) across 14 centers from 9 countries, and to explore the influence of site characteristics and exposure assessment methods on between-center heterogeneity in this association.<\/jats:p>\n                  <jats:p>Methods: Using a common analytical protocol, International Collaboration on Air Pollution and Pregnancy Outcomes (ICAPPO) centers generated effect estimates for term LBW and continuous birth weight associated with PM10 and PM2.5 (particulate matter \u2264 10 and 2.5 \u00b5m). We used meta-analysis to combine the estimates of effect across centers (~ 3 million births) and used meta-regression to evaluate the influence of center characteristics and exposure assessment methods on between-center heterogeneity in reported effect estimates.<\/jats:p>\n                  <jats:p>Results: In random-effects meta-analyses, term LBW was positively associated with a 10-\u03bcg\/m3 increase in PM10 [odds ratio (OR) = 1.03; 95% CI: 1.01, 1.05] and PM2.5 (OR = 1.10; 95% CI: 1.03, 1.18) exposure during the entire pregnancy, adjusted for maternal socioeconomic status. A 10-\u03bcg\/m3 increase in PM10 exposure was also negatively associated with term birth weight as a continuous outcome in the fully adjusted random-effects meta-analyses (\u20138.9 g; 95% CI: \u201313.2, \u20134.6 g). Meta-regressions revealed that centers with higher median PM2.5 levels and PM2.5:PM10 ratios, and centers that used a temporal exposure assessment (compared with spatiotemporal), tended to report stronger associations.<\/jats:p>\n                  <jats:p>Conclusion: Maternal exposure to particulate pollution was associated with LBW at term across study populations. We detected three site characteristics and aspects of exposure assessment methodology that appeared to contribute to the variation in associations reported by centers.<\/jats:p>","DOI":"10.1289\/ehp.1205575","type":"journal-article","created":{"date-parts":[[2013,2,6]],"date-time":"2013-02-06T08:17:40Z","timestamp":1360138660000},"page":"267-373","source":"Crossref","is-referenced-by-count":375,"title":["Maternal Exposure to Particulate Air Pollution and Term Birth Weight: A Multi-Country Evaluation of Effect and Heterogeneity"],"prefix":"10.1021","volume":"121","author":[{"given":"Payam","family":"Dadvand","sequence":"first","affiliation":[{"name":"Centre for Research in Environmental Epidemiology (CREAL), Barcelona, Spain"},{"name":"Municipal Institute of Medical Research (IMIM-Hospital del Mar), Barcelona, Spain"},{"name":"CIBER Epidemiologia y Salud P\u00fablica (CIBERESP), Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer","family":"Parker","sequence":"additional","affiliation":[{"name":"National Center for Health Statistics, Centers for Disease Control and Prevention, Hyattsville, Maryland, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michelle L.","family":"Bell","sequence":"additional","affiliation":[{"name":"School of Forestry and Environmental Studies, Yale University, New Haven, Connecticut, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matteo","family":"Bonzini","sequence":"additional","affiliation":[{"name":"Department of Clinical and Experimental Medicine, University of Insubria, Varese, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Brauer","sequence":"additional","affiliation":[{"name":"University of British Columbia, School of Population and Public Health, Vancouver, British Columbia, 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Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eun-hee","family":"Ha","sequence":"additional","affiliation":[{"name":"Department of Preventive Medicine, Ewha Womans University, Seoul, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jong Han","family":"Leem","sequence":"additional","affiliation":[{"name":"Department of Occupational and Environmental Medicine, Inha University, Incheon, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edith H.","family":"van den Hooven","sequence":"additional","affiliation":[{"name":"Generation R Study Group, Erasmus Medical Center, Rotterdam, the Netherlands"},{"name":"Urban Environment and Safety, TNO, Utrecht, the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bin","family":"Jalaludin","sequence":"additional","affiliation":[{"name":"Centre for Research, Evidence Management and Surveillance, Sydney, Australia"},{"name":"South 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France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rachel","family":"Morello-Frosch","sequence":"additional","affiliation":[{"name":"Department of Environmental Science, Policy, and Management, University of California\u2013Berkeley, Berkeley, California, USA"},{"name":"School of Public Health, University of California\u2013Berkeley, Berkeley, California, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Geoffrey G.","family":"Morgan","sequence":"additional","affiliation":[{"name":"North Coast Area Health Service, Lismore, New South Wales, Australia"},{"name":"University Centre for Rural Health\u2013North Coast, University of Sydney, Sydney, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angela Cecilia","family":"Pesatori","sequence":"additional","affiliation":[{"name":"Department of Occupational and Environmental Health, Universit\u00e0 di Milano, Milan, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank H.","family":"Pierik","sequence":"additional","affiliation":[{"name":"Urban Environment and Safety, TNO, Utrecht, the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tanja","family":"Pless-Mulloli","sequence":"additional","affiliation":[{"name":"Institute of Health & Society, Newcastle University, Newcastle upon Tyne, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David Q.","family":"Rich","sequence":"additional","affiliation":[{"name":"Department of Public Health Sciences, University of Rochester School of Medicine and Dentistry, Rochester, New York, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sheela","family":"Sathyanarayana","sequence":"additional","affiliation":[{"name":"Seattle Children\u2019s Research Institute, University of Washington, Seattle, Washington, 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