{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T06:53:30Z","timestamp":1791269610257,"version":"4.1.0"},"reference-count":35,"publisher":"American Chemical Society (ACS)","issue":"8","license":[{"start":{"date-parts":[[2017,12,29]],"date-time":"2017-12-29T00:00:00Z","timestamp":1514505600000},"content-version":"vor","delay-in-days":1001,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2015,8,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>There is limited knowledge about the extent to which estimates of air pollution effects on health are affected by the choice for a specific exposure model.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>We aimed to evaluate the correlation between long-term air pollution exposure estimates using two commonly used exposure modeling techniques [dispersion and land use regression (LUR) models] and, in addition, to compare the estimates of the association between long-term exposure to air pollution and lung function in children using these exposure modeling techniques.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We used data of 1,058 participants of a Dutch birth cohort study with measured forced expiratory volume in 1 sec (FEV1), forced vital capacity (FVC), and peak expiratory flow (PEF) measurements at 8 years of age. For each child, annual average outdoor air pollution exposure [nitrogen dioxide (NO2), mass concentration of particulate matter with diameters \u2264 2.5 and \u2264 10 \u03bcm (PM2.5, PM10), and PM2.5 soot] was estimated for the current addresses of the participants by a dispersion and a LUR model. Associations between exposures to air pollution and lung function parameters were estimated using linear regression analysis with confounder adjustment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Correlations between LUR- and dispersion-modeled pollution concentrations were high for NO2, PM2.5, and PM2.5 soot (R = 0.86\u20130.90) but low for PM10 (R = 0.57). Associations with lung function were similar for air pollutant exposures estimated using LUR and dispersion modeling, except for associations of PM2.5 with FEV1 and FVC, which were stronger but less precise for exposures based on LUR compared with dispersion model.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Predictions from LUR and dispersion models correlated very well for PM2.5, NO2, and PM2.5 soot but not for PM10. Health effect estimates did not depend on the type of model used to estimate exposure in a population of Dutch children.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Citation<\/jats:title>\n                    <jats:p>Wang M, Gehring U, Hoek G, Keuken M, Jonkers S, Beelen R, Eeftens M, Postma DS, Brunekreef B. 2015. Air pollution and lung function in Dutch children: a comparison of exposure estimates and associations based on land use regression and dispersion exposure modeling approaches. Environ Health Perspect 123:847\u2013851;\u2002http:\/\/dx.doi.org\/10.1289\/ehp.1408541<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1289\/ehp.1408541","type":"journal-article","created":{"date-parts":[[2015,4,3]],"date-time":"2015-04-03T12:12:20Z","timestamp":1428063140000},"page":"847-851","source":"Crossref","is-referenced-by-count":50,"title":["Air Pollution and Lung Function in Dutch Children: A Comparison of Exposure Estimates and Associations Based on Land Use Regression and Dispersion Exposure Modeling Approaches"],"prefix":"10.1021","volume":"123","author":[{"given":"Meng","family":"Wang","sequence":"first","affiliation":[{"name":"Institute for Risk Assessment Sciences, Utrecht University, Utrecht, the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ulrike","family":"Gehring","sequence":"additional","affiliation":[{"name":"Institute for Risk Assessment Sciences, Utrecht University, Utrecht, the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gerard","family":"Hoek","sequence":"additional","affiliation":[{"name":"Institute for Risk Assessment Sciences, Utrecht University, Utrecht, the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Menno","family":"Keuken","sequence":"additional","affiliation":[{"name":"TNO, Netherlands Organisation for Applied Scientific Research, Utrecht, the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sander","family":"Jonkers","sequence":"additional","affiliation":[{"name":"TNO, Netherlands Organisation for Applied Scientific Research, Utrecht, the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rob","family":"Beelen","sequence":"additional","affiliation":[{"name":"Institute for Risk Assessment Sciences, Utrecht University, Utrecht, the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marloes","family":"Eeftens","sequence":"additional","affiliation":[{"name":"Institute for Risk Assessment Sciences, Utrecht University, Utrecht, the Netherlands"},{"name":"Swiss Tropical and Public Health Institute, Basel, Switzerland"},{"name":"University of Basel, Basel, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dirkje S.","family":"Postma","sequence":"additional","affiliation":[{"name":"University of Groningen, Department of Pulmonology, University Medical Center Groningen, Groningen, the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bert","family":"Brunekreef","sequence":"additional","affiliation":[{"name":"Institute for Risk Assessment Sciences, Utrecht University, Utrecht, the Netherlands"},{"name":"Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2015,4,3]]},"reference":[{"key":"2026080606030975700_micit1","doi-asserted-by":"crossref","first-page":"634","DOI":"10.1016\/j.atmosenv.2012.01.064","article-title":"Effect of the number of measurement sites on land use regression models in estimating local air pollution.","volume":"54","author":"Basaga\u00f1a","year":"2012","journal-title":"Atmos Environ"},{"issue":"6","key":"2026080606030975700_micit2","doi-asserted-by":"crossref","first-page":"654","DOI":"10.1038\/jes.2013.62","article-title":"Exposure prediction approaches used in air pollution epidemiology studies: key findings and future recommendations.","volume":"23","author":"Baxter","year":"2013","journal-title":"J Expo Sci Environ Epidemiol"},{"key":"2026080606030975700_micit3","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.atmosenv.2013.02.037","article-title":"Development of NO2 and NOx land use regression models for estimating air pollution exposure in 36 study areas in Europe\u2014the ESCAPE project.","volume":"72","author":"Beelen","year":"2013","journal-title":"Atmos Environ"},{"key":"2026080606030975700_micit4","doi-asserted-by":"crossref","first-page":"4614","DOI":"10.1016\/j.atmosenv.2010.08.005","article-title":"Comparison of the performances of land use regression modelling and dispersion modelling in estimating small-scale variations in long-term air pollution concentrations in a Dutch urban area.","volume":"44","author":"Beelen","year":"2010","journal-title":"Atmos Environ"},{"key":"2026080606030975700_micit5","doi-asserted-by":"publisher","first-page":"680","DOI":"10.1289\/ehp.10952","article-title":"A cohort study of traffic-related air pollution impacts on birth outcomes.","volume":"116","author":"Brauer","year":"2008","journal-title":"Environ Health Perspect"},{"key":"2026080606030975700_micit6","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/S0048-9697(00)00429-0","article-title":"A regression-based method for mapping traffic-related air pollution: application and testing in four contrasting urban environments.","volume":"253","author":"Briggs","year":"2000","journal-title":"Sci Total Environ"},{"issue":"suppl 15","key":"2026080606030975700_micit7","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1034\/j.1399-3038.13.s.15.1.x","article-title":"The Prevention and Incidence of Asthma and Mite Allergy (PIAMA) birth cohort study: design and first results.","volume":"13","author":"Brunekreef","year":"2002","journal-title":"Pediatr Allergy Immunol"},{"key":"2026080606030975700_micit8","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1016\/j.atmosenv.2012.07.080","article-title":"Variation of NO2 and NOx concentrations between and within 36 European study areas: results from the ESCAPE study.","volume":"62","author":"Cyrys","year":"2012","journal-title":"Atmos Environ"},{"key":"2026080606030975700_micit9","doi-asserted-by":"crossref","first-page":"987","DOI":"10.1289\/ehp.7662","article-title":"GIS-based estimation of exposure to particulate matter and NO2 in an urban area: stochastic versus dispersion modeling.","volume":"113","author":"Cyrys","year":"2005","journal-title":"Environ Health Perspect"},{"key":"2026080606030975700_micit10","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1016\/j.envint.2014.08.011","article-title":"Comparing land use regression and dispersion modelling to assess residential exposure to ambient air pollution for epidemiological studies.","volume":"73","author":"de Hoogh","year":"2014","journal-title":"Environ Int"},{"key":"2026080606030975700_micit11","doi-asserted-by":"publisher","first-page":"670","DOI":"10.1289\/ehp.0901818","article-title":"A comparison of different approaches to estimate small-scale spatial variation in outdoor NO2 concentrations.","volume":"119","author":"Dijkema","year":"2011","journal-title":"Environ Health Perspect"},{"key":"2026080606030975700_micit12","doi-asserted-by":"crossref","first-page":"2338","DOI":"10.1056\/NEJMoa073625","article-title":"Reduced exposure to PM10 and attenuated age-related decline in lung function.","volume":"357","author":"Downs","year":"2007","journal-title":"N Engl J Med"},{"key":"2026080606030975700_micit13","doi-asserted-by":"crossref","first-page":"11195","DOI":"10.1021\/es301948k","article-title":"Development of land use regression models for PM2.5, PM2.5 absorbance, PM10 and PMcoarse in 20 European study areas; results of the ESCAPE project.","volume":"46","author":"Eeftens","year":"2012","journal-title":"Environ Sci Technol"},{"key":"2026080606030975700_micit14","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1016\/j.atmosenv.2012.08.038","article-title":"Spatial variation of PM2.5, PM10, PM2.5 absorbance and PMcoarse concentrations between and within 20 European study areas and the relationship with NO2\u2014results of the ESCAPE project.","volume":"62","author":"Eeftens","year":"2012","journal-title":"Atmos Environ"},{"issue":"2","key":"2026080606030975700_micit15","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1111\/j.1398-9995.2011.02739.x","article-title":"The 8-year follow-up of the PIAMA intervention study assessing the effect of mite-impermeable mattress covers.","volume":"67","author":"Gehring","year":"2012","journal-title":"Allergy"},{"key":"2026080606030975700_micit16","doi-asserted-by":"publisher","first-page":"1357","DOI":"10.1289\/ehp.1306770","article-title":"Air pollution exposure and lung function in children: the ESCAPE project.","volume":"121","author":"Gehring","year":"2013","journal-title":"Environ Health Perspect"},{"key":"2026080606030975700_micit17","doi-asserted-by":"crossref","first-page":"7072","DOI":"10.1016\/j.atmosenv.2011.09.042","article-title":"Comparative assessment of GIS-based methods and metrics for estimating long-term exposures to air pollution.","volume":"45","author":"Gulliver","year":"2011","journal-title":"Atmos Environ"},{"key":"2026080606030975700_micit18","doi-asserted-by":"publisher","first-page":"1054","DOI":"10.1289\/ehp.1206016","article-title":"Impact of geocoding methods on associations between long-term exposure to urban air pollution and lung function.","volume":"121","author":"Jacquemin","year":"2013","journal-title":"Environ Health Perspect"},{"key":"2026080606030975700_micit19","doi-asserted-by":"publisher","first-page":"1691","DOI":"10.1289\/ehp.1003369","article-title":"Black carbon as an additional indicator of the adverse health effects of airborne particles compared with PM10 and PM2.5.","volume":"119","author":"Janssen","year":"2011","journal-title":"Environ Health Perspect"},{"key":"2026080606030975700_micit20","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1038\/sj.jea.7500388","article-title":"A review and evaluation of intraurban air pollution exposure models.","volume":"15","author":"Jerrett","year":"2005","journal-title":"J Expo Anal Environ Epidemiol"},{"key":"2026080606030975700_micit21","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1097\/01.ede.0000181630.15826.7d","article-title":"Spatial analysis of air pollution and mortality in Los Angeles.","volume":"16","author":"Jerrett","year":"2005","journal-title":"Epidemiology"},{"key":"2026080606030975700_micit22","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/j.atmosenv.2013.03.010","article-title":"Modelling elemental carbon at regional, urban and traffic locations in the Netherlands.","volume":"73","author":"Keuken","year":"2013","journal-title":"Atmos Environ"},{"key":"2026080606030975700_micit23","doi-asserted-by":"crossref","first-page":"1359","DOI":"10.1016\/j.atmosenv.2007.08.012","article-title":"Within-urban variability in ambient air pollution: comparison of estimation methods.","volume":"42","author":"Marshall","year":"2008","journal-title":"Atmos Environ"},{"key":"2026080606030975700_micit24","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1056\/NEJMoa054409","article-title":"Long-term exposure to air pollution and incidence of cardiovascular events in women.","volume":"356","author":"Miller","year":"2007","journal-title":"N Engl J Med"},{"key":"2026080606030975700_micit25","doi-asserted-by":"publisher","first-page":"1232","DOI":"10.1289\/ehp.1205961","article-title":"Long-term exposure to PM10 and NO2 in association with lung volume and airway resistance in the MAAS birth cohort.","volume":"121","author":"M\u00f6lter","year":"2013","journal-title":"Environ Health Perspect"},{"key":"2026080606030975700_micit26","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1097\/EDE.0b013e31815c0827","article-title":"Residential outdoor air pollution and lung function in schoolchildren.","volume":"19","author":"Oftedal","year":"2008","journal-title":"Epidemiology"},{"key":"2026080606030975700_micit27","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1038\/jes.2013.15","article-title":"Air pollution exposure prediction approaches used in air pollution epidemiology studies.","volume":"23","author":"\u00d6zkaynak","year":"2013","journal-title":"J Expo Sci Environ Epidemiol"},{"key":"2026080606030975700_micit28","doi-asserted-by":"crossref","first-page":"1286","DOI":"10.1164\/rccm.201206-1045OC","article-title":"Traffic-related air pollution and lung function in children at 8 years of age: a birth cohort study.","volume":"186","author":"Schultz","year":"2012","journal-title":"Am J Respir Crit Care Med"},{"key":"2026080606030975700_micit29","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/j.envint.2014.02.001","article-title":"Health effects of ambient air pollution: do different methods for estimating exposure lead to different results?","volume":"66","author":"Sellier","year":"2014","journal-title":"Environ Int"},{"key":"2026080606030975700_micit30","author":"van Jaarsveld JA.","year":"2004"},{"key":"2026080606030975700_micit31","doi-asserted-by":"crossref","first-page":"3060","DOI":"10.1016\/j.atmosenv.2009.03.029","article-title":"Likelihood of meeting the EU limit values for NO2 and PM10 concentrations in the Netherlands.","volume":"43","author":"Velders","year":"2009","journal-title":"Atmos Environ"},{"key":"2026080606030975700_micit32","doi-asserted-by":"crossref","first-page":"4357","DOI":"10.1021\/es305129t","article-title":"Evaluation of land use regression models for NO2 and particulate matter in 20 European study areas: the ESCAPE project.","volume":"47","author":"Wang","year":"2013","journal-title":"Environ Sci Technol"},{"key":"2026080606030975700_micit33","article-title":"An intercomparison of the TNO traffic models, field data and wind tunnel measurements. TNO Report 2003\/207","author":"Wesseling JP.","year":"2003"},{"key":"2026080606030975700_micit34","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1093\/ije\/dys231","article-title":"Cohort profile: the Prevention and Incidence of Asthma and Mite Allergy (PIAMA) birth cohort.","volume":"43","author":"Wijga","year":"2014","journal-title":"Int J Epidemiol"},{"key":"2026080606030975700_micit35","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1016\/j.envres.2011.03.008","article-title":"Comparing exposure assessment methods for traffic-related air pollution in an adverse pregnancy outcome study.","volume":"111","author":"Wu","year":"2011","journal-title":"Environ Res"}],"container-title":["Environmental Health Perspectives"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/evhpaz\/article-pdf\/123\/8\/847\/66431817\/ehp.1408541.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/pubs.acs.org\/evhpaz\/article-pdf\/123\/8\/847\/66431817\/ehp.1408541.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T13:48:19Z","timestamp":1786628899000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/evhpaz\/article-lookup\/doi\/10.1289\/ehp.1408541"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,4,3]]},"references-count":35,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2015,4,3]]},"published-print":{"date-parts":[[2015,8,1]]}},"URL":"https:\/\/doi.org\/10.1289\/ehp.1408541","relation":{},"ISSN":["0091-6765","1552-9924"],"issn-type":[{"value":"0091-6765","type":"print"},{"value":"1552-9924","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,4,3]]}}}