{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T23:34:28Z","timestamp":1788305668017,"version":"build-2803163510"},"reference-count":34,"publisher":"American Chemical Society (ACS)","issue":"6","license":[{"start":{"date-parts":[[2017,12,29]],"date-time":"2017-12-29T00:00:00Z","timestamp":1514505600000},"content-version":"vor","delay-in-days":752,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2016,6,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Many women of childbearing age are occupationally active, which leads to a large number of pregnancies potentially exposed to occupational exposures. Occupational noise has been identified as a risk factor for hearing impairment in adults. However, very few studies have assessed the effect of occupational noise on the fetus.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives:<\/jats:title>\n                    <jats:p>The aim of this study was to investigate whether occupational exposure to noise during pregnancy is associated with hearing dysfunction in children.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>This population based cohort study included 1,422,333 single births in Sweden 1986\u20132008. Data on mothers\u2019 occupation, smoking habits, age, ethnicity, body mass index, leave of absence, and socioeconomic factors were obtained from interviews performed by prenatal care unit staff at approximately 10 weeks of gestation and from national registers. Occupational noise exposure was classified by a job\u2013exposure-matrix as &amp;lt; 75, 75\u201384, or \u2265 85 dBLAeq,8h. Diagnosed cases of hearing dysfunction (ICD-10 codes H90.3-7, 91.0, 91.2-3, 91.8, 93.1-2) were identified from a register of specialized medical care. Cox proportional hazards models were used to estimate associations.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>In the full sample, containing a mixture of part-time and full-time workers during pregnancy, the adjusted HR for hearing dysfunction associated with maternal occupational noise exposure \u2265 85 vs. &amp;lt; 75 dBLAeq,8h was 1.27 (95% CI: 0.99, 1.64; 60 exposed cases). When restricted to children whose mothers worked full-time and had &amp;lt; 20 days leave of absence during pregnancy, the corresponding HR was 1.82 (95% CI: 1.08, 3.08; 14 exposed cases).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>This study showed an association between occupational noise exposure during pregnancy and hearing dysfunction in children. In view of mechanistic evidence and earlier indicative epidemiological and experimental findings, the results support that pregnant women should not be exposed to high levels of noise at work.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Citation:<\/jats:title>\n                    <jats:p>Selander J, Albin M, Rosenhall U, Rylander L, Lewn\u00e9 M, Gustavsson P. 2016. Maternal occupational exposure to noise during pregnancy and hearing dysfunction in children: a nationwide prospective cohort study in Sweden. Environ Health Perspect 124:855\u2013860;\u2002http:\/\/dx.doi.org\/10.1289\/ehp.1509874<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1289\/ehp.1509874","type":"journal-article","created":{"date-parts":[[2015,12,9]],"date-time":"2015-12-09T13:41:31Z","timestamp":1449668491000},"page":"855-860","source":"Crossref","is-referenced-by-count":49,"title":["Maternal Occupational Exposure to Noise during Pregnancy and Hearing Dysfunction in Children: A Nationwide Prospective Cohort Study in Sweden"],"prefix":"10.1021","volume":"124","author":[{"given":"Jenny","family":"Selander","sequence":"first","affiliation":[{"name":"Institute of Environmental Medicine, Unit of Occupational Medicine, Karolinska Institutet, Stockholm, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Albin","sequence":"additional","affiliation":[{"name":"Institute of Environmental Medicine, Unit of Occupational Medicine, Karolinska Institutet, Stockholm, Sweden"},{"name":"Centre for Occupational and Environmental Medicine at Stockholm County Council, Stockholm, Sweden"},{"name":"Division of Occupational and Environmental Medicine, Lund University, Lund, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ulf","family":"Rosenhall","sequence":"additional","affiliation":[{"name":"Department of Audiology and Neurotology, Karolinska University Hospital, Stockholm, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lars","family":"Rylander","sequence":"additional","affiliation":[{"name":"Division of Occupational and Environmental Medicine, Lund University, Lund, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie","family":"Lewn\u00e9","sequence":"additional","affiliation":[{"name":"Institute of Environmental Medicine, Unit of Occupational Medicine, Karolinska Institutet, Stockholm, Sweden"},{"name":"Centre for Occupational and Environmental Medicine at Stockholm County Council, Stockholm, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Per","family":"Gustavsson","sequence":"additional","affiliation":[{"name":"Institute of Environmental Medicine, Unit of Occupational Medicine, Karolinska Institutet, Stockholm, Sweden"},{"name":"Centre for Occupational and Environmental Medicine at Stockholm County Council, Stockholm, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2015,12,8]]},"reference":[{"key":"2026080506031617500_micit1","first-page":"4","article-title":"Arbetsmilj\u00f6n 2011 (The Work Environment 2011) [in Swedish].","volume-title":"Report","author":"Arbetsmilj\u00f6verket (Swedish Work Environment Authority)","year":"2012"},{"key":"2026080506031617500_micit2","doi-asserted-by":"crossref","first-page":"1173","DOI":"10.1126\/science.7375927","article-title":"The fetal sound environment of 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